<html><head></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; color: rgb(0, 0, 0); font-size: 14px; font-family: Calibri, sans-serif;"><div><div>Had to shorten this…hope it doesn’t post twice as it went to the moderator because of size.</div><span id="OLK_SRC_BODY_SECTION"><div><br></div><div><div style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;"><div>Good to know about the liver test. I will NOT mention it to my vet. </div><div><br></div><div>Since this whole process has started for Bogey and I, I often wonder what logic is used when saying that the side affects from taking the Stanzolol are liver issues, but the side effect of not taking it, is death. I know for me personally, if I was sick and facing this decision, I know what I would do without question. Believe it or not, I read that exact paper you are describing when Bogey was first prescribed the Stanzolol. (Google search) I felt pretty defeated (although many of the terms were over my head) after reading it. I did not notice the dosages though. Doesn’t sound like a very scientific study does it. Maybe we should start our own. Post the names of vets who are willing to prescribe it as well as the results each person has with their pet that is taking it. There again, I am way out in front of myself here because Bogey is not thriving but she did just run into the room with a Q-tip in her mouth (her favorite toy) and 60 days ago she could barely walk into the room without laying down. She has also steadily gained weight. Over a pound which doesn’t sound like much but she barely weighed 5 pounds to begin with. Life is still happening here.</div><div><br></div><div>It does seem like there is secrecy surrounding vets prescribing Stanzolol. Almost like I am scoring some heroin or something. (no I am not a drug user) From what you found with your other cat, clearly this could be a positive choice for inoperable tumors, and or life extending treatment for senior pets. At any rate, I feel luckier each day that my current vet values the life of my cat enough to try to save her. It sounds like your vet is terrific and that you have a great, long relationship with them. I hope to have the same, one day.</div><div><br></div><div>Sherri</div></div></div></span></div><div><br></div><span id="OLK_SRC_BODY_SECTION"><div style="font-family:Calibri; font-size:11pt; text-align:left; color:black; BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; PADDING-BOTTOM: 0in; PADDING-LEFT: 0in; PADDING-RIGHT: 0in; BORDER-TOP: #b5c4df 1pt solid; BORDER-RIGHT: medium none; PADDING-TOP: 3pt"><span style="font-weight:bold">From: </span> Felvtalk <<a href="mailto:felvtalk-bounces@felineleukemia.org">felvtalk-bounces@felineleukemia.org</a>> on behalf of Amani Oakley <<a href="mailto:aoakley@oakleylegal.com">aoakley@oakleylegal.com</a>><br><span style="font-weight:bold">Reply-To: </span> <<a href="mailto:felvtalk@felineleukemia.org">felvtalk@felineleukemia.org</a>><br><span style="font-weight:bold">Date: </span> Friday, September 30, 2016 at 8:29 PM<br><span style="font-weight:bold">To: </span> "<a href="mailto:felvtalk@felineleukemia.org">felvtalk@felineleukemia.org</a>" <<a href="mailto:felvtalk@felineleukemia.org">felvtalk@felineleukemia.org</a>><br><span style="font-weight:bold">Subject: </span> [Felvtalk] FW: FW: Continued Improvement for Bogey on Stanzolol<br></div><div><br></div><div xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"><meta http-equiv="Content-Type" content="text/html; charset=us-ascii"><meta name="Generator" content="Microsoft Word 14 (filtered medium)"><style><!--
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</o:shapelayout></xml><![endif]--><div lang="EN-CA" link="blue" vlink="purple"><div class="WordSection1"><p class="MsoNormal"><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);">Sherri<o:p></o:p></span></p><p class="MsoNormal"><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);"><o:p> </o:p></span></p><p class="MsoNormal"><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);">I wouldn’t recommend you run the liver enzymes. If they rise (and they often do) it will cause your vet to try to get you to stop the Winstrol.<o:p></o:p></span></p><p class="MsoNormal"><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);"><o:p> </o:p></span></p><p class="MsoNormal"><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);">I was running a full biochemistry profile along with the full haematology profile on Zander. So tests like ALP, AST, ALT, TBili and DBili are indicators of liver
function. With Zander, they rose sharply, but there was simply no other option but to continue. I had done all my research, tried out the two most likely new and promising therapies (LTCI and Interferon) and they were not at all (I mean AT ALL) helpful. So,
discontinuing the Winstrol meant certain death for Zander. I am so glad I ignored the liver enzymes. They settled down on their own, and Zander never had any liver problems after almost a FULL YEAR on Winstrol.<o:p></o:p></span></p><p class="MsoNormal"><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);"><o:p> </o:p></span></p><p class="MsoNormal"><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);">I had another cat with a nasal sarcoma, who was 16 when she got the sarcoma and a tiny skinny thing. I put her on Winstrol because again, there were no really
good options. Again, I had a great response, with it upping her appetite dramatically, and keeping the sarcoma in a shrunken state with far less discharge and swelling than prior to the administration of the Winstrol. Her liver enzymes went through the roof
and the vet (a very good friend of mine who is the head of vet oncology and a brilliant man) knowing how I feel about Winstrol, just asked if I would agree to discontinue the Winstrol to see if the liver enzymes would reduce. (Very gently. He knew he was on
thin ice.) I did, for a few weeks, then put her back on. She lived to age 19 with that sarcoma, because the Winstrol kept her eating, and happy and strong.<o:p></o:p></span></p><p class="MsoNormal"><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);"><o:p> </o:p></span></p><p class="MsoNormal"><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);">One of the smart folks on this chatline, recently sent me what was likely the stupid vet research publication which likely started the whole “liver” scare. Look
it up because I cannot attach it to this email as it will not go through. The title is, “Hepatotoxicity of stanozolol in cats” by Kenneth R. Harkin, et. al. in JAVMA, Vol. 217, No. 5, September 1, 2000. Bizarrely, in this study, the authors put the cats on
a “loading dose” of </span><b><span style="font-size: 10pt; font-family: Arial, sans-serif; color: red;">25 mg intramuscularly</span></b><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);">, then
</span><b><span style="font-size: 10pt; font-family: Arial, sans-serif; color: red;">2 mg a day by mouth, every 12 hours</span></b><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);">. So, just for starters, you see that for some reason,
they started the cats on </span><b><span style="font-size: 10pt; font-family: Arial, sans-serif; color: red;">TEN TIMES the normal dose</span></b><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);">, and them kept them on at least
</span><b><span style="font-size: 10pt; font-family: Arial, sans-serif; color: red;">TWO TIMES the normal dose</span></b><span style="font-size: 10pt; font-family: Arial, sans-serif; color: red;"></span><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);">for the rest of the study. Even then, here are some telltale pieces of information:<o:p></o:p></span></p><p class="MsoNormal"><br></p><p class="MsoNormal"><span style="font-size: 10pt; font-family: Arial, sans-serif; color: rgb(31, 73, 125);"><o:p> </o:p></span></p></div></div></div></span></body></html>