<div dir="ltr"><div dir="ltr" style="font-size:12.8px">Thanks for the advice re. the winstrol. I am honestly concerned about him making it past the next few days.<div><br></div><div>His abdomen is really sore/tense/uncomfortable and he complains heavily when being moved/picked up/palpated. Do you have any idea if that fits with the FeLV?</div></div><div class="" style="font-size:12.8px"><div id=":3jc" class="" tabindex="0" style="border:1px solid rgb(221,221,221);background-color:rgb(241,241,241)"><img class="" src="https://ssl.gstatic.com/ui/v1/icons/mail/images/cleardot.gif"></div></div></div><div class="gmail_extra"><br><div class="gmail_quote">On Mon, Oct 19, 2015 at 11:59 AM, Amani Oakley <span dir="ltr"><<a href="mailto:aoakley@oakleylegal.com" target="_blank">aoakley@oakleylegal.com</a>></span> wrote:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex">
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<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d">Maya<u></u><u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d"><u></u> <u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d">I would be pretty sure that the platelet drop is from FeLV and I am not sure why that is stumping the vets. FeLV can attack any one of the three cell lines (red
cells, white cells and platelets) because it effects the bone marrow where these cells are all produced. Thus, when FeLV begins to affect a cat, you can get a drop in one or two or all three of the cell lines.<u></u><u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d"><u></u> <u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d">In addition to the treatment he is getting, ask the vet to put him on Winstrol. I have posted here many times, and will again, that Winstrol is the only medication
I found effective that actually turned back on the cell production of the bone marrow. He can remain on the prednisolone and the Doxycycline. Even though the Doxycycline is an antibiotic and thus not effective against viruses, my vets have said that they have
gotten some positive results from using it with FeLV cats. I used it with my cat, in addition to the Prednisolone and the Winstrol, but having used the Doxycycline and Prednisolone WITHOUT the Winstrol first, I can confirm that it was the Winstrol that did
the trick (confirmed by weekly monitoring of my cat’s blood work – checking specifically for haematocrit levels, RBC levels, Reticulocyte levels, white cells (total, neutrophils and leukocytes) and platelet counts. (I have posted this before, but just so that
you know, before moving to Winstrol, I had my cat on Interferon – which did nothing to his blood work results at all – and then LTCI – which again had no positive result on the bloodwork.)<u></u><u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d"><u></u> <u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d">Winstrol (Stanozolol) is an anabolic steroid which usually is required to be ordered from a compounding pharmacy. The dose I used was 1 mg 2x a day.<u></u><u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d"><u></u> <u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d">If you want to confirm the effectiveness as I did, place Merlot on the Winstrol and after a week or two, run his haematology blood work again. You should start
seeing a nudging up of the red cells, although the platelet counts in my cat at least, were the last to respond to the Winstrol. Don’t give up if there is no change in 2 weeks, and you will likely also get a bump up in his appetite and his general feeling
of wellbeing (playing, purring, etc.)<u></u><u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d"><u></u> <u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d">Merlot may start having his liver enzymes rise. Resist the urge or the advice of your vet to discontinue the Winstrol. The liver enzymes will very likely drop
after he is weaned off the Winstrol, and for the time being, the more important thing is to deal with his failing bone marrow.<u></u><u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d"><u></u> <u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d">Amani<u></u><u></u></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial","sans-serif";color:#1f497d"><u></u> <u></u></span></p>
<p class="MsoNormal"><b><span lang="EN-US" style="font-size:10.0pt;font-family:"Tahoma","sans-serif"">From:</span></b><span lang="EN-US" style="font-size:10.0pt;font-family:"Tahoma","sans-serif""> Felvtalk [mailto:<a href="mailto:felvtalk-bounces@felineleukemia.org" target="_blank">felvtalk-bounces@felineleukemia.org</a>]
<b>On Behalf Of </b>Maya D'Alessio<br>
<b>Sent:</b> October-19-15 10:10 AM<br>
<b>To:</b> <a href="mailto:felvtalk@felineleukemia.org" target="_blank">felvtalk@felineleukemia.org</a><br>
<b>Subject:</b> Re: [Felvtalk] Merlot<u></u><u></u></span></p><div><div class="h5">
<p class="MsoNormal"><u></u> <u></u></p>
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<p class="MsoNormal"><span style="font-size:9.5pt">Merlot was admitted to the vet hospital this morning. His fever is persisting and we still have no idea as to cause. Last night they tested for pancreatitis and that test came back normal. He got sub-Q fluids
and they sent him home with us. He has vomitted a few times and he has not really kept down any nutrition since Saturday morning. They just did an x-ray but there is no obvious issue. They are going to do a barium contrast imaging series now after they administer
IV fluids and antibiotics in hope that his fever will come down.</span><u></u><u></u></p>
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<p class="MsoNormal"><span style="font-size:9.5pt"><u></u> <u></u></span></p>
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<p class="MsoNormal"><span style="font-size:9.5pt">The worst part is that we still really have no idea what is going on, so I am just waiting to hear and worrying :(<u></u><u></u></span></p>
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<p class="MsoNormal"><u></u> <u></u></p>
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<p class="MsoNormal">On Sun, Oct 18, 2015 at 3:34 PM, Marsha <<a href="mailto:martia@lynxe.com" target="_blank">martia@lynxe.com</a>> wrote:<u></u><u></u></p>
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<p class="MsoNormal">Treatment depends on the cause of the low platelet count. If it's low enough that blood can't clot properly, he could develop internal bleeds from minor events, and become anemic or worse. If the cause was his immune system attacking
his own platelets, the treatment might be prednisolone to suppress his immune system. But if he's FeLV+, that's not so likely. Platelet deficiency is called thrombocytopenia.<span style="color:#888888"><br>
<br>
<span>Marsha</span></span><u></u><u></u></p>
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On 10/18/2015 1:54 PM, Maya D'Alessio wrote:<u></u><u></u></p>
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<blockquote style="margin-top:5.0pt;margin-bottom:5.0pt">
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<p class="MsoNormal"><span style="font-size:9.5pt">Hey everyone,</span> <u></u><u></u></p>
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<p class="MsoNormal"><span style="font-size:9.5pt"><u></u> <u></u></span></p>
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<p class="MsoNormal"><span style="font-size:9.5pt">Merlot is my 3.5 year old cat. Last summer my other cat passed away from FeLV (we had no idea she had it), and we had Merlot tested. He tests + on the snap/pcr test, but - on the ELISA. This gave me a little
bit of piece of mind, in the hope that he would not become persistently +.<u></u><u></u></span></p>
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<div>
<p class="MsoNormal"><span style="font-size:9.5pt"><u></u> <u></u></span></p>
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<div>
<p class="MsoNormal"><span style="font-size:9.5pt">Last night he was completely uninterested in dinner (very unusual for him), and he seemed a bit warm and lethargic. I took him in to the vets this morning and they wanted to do bloodwork. He has a temperature
of 40.5 C. First results come back all normal except a very low platelet count. <u></u><u></u></span></p>
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<p class="MsoNormal"><span style="font-size:9.5pt"><u></u> <u></u></span></p>
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<div>
<p class="MsoNormal"><span style="font-size:9.5pt">They gave him a small dosage of prednisone, and a shot of penicillin and sent me home with doxycillin and some food to force feed him if he won't eat on his own. They want me to watch him and come back in to
the vets in 3 days to re-test his blood.<u></u><u></u></span></p>
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<p class="MsoNormal"><span style="font-size:9.5pt"><u></u> <u></u></span></p>
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<p class="MsoNormal"><span style="font-size:9.5pt">Any experience with low platelet count, what that means and if there is any treatment?
<u></u><u></u></span></p>
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<p class="MsoNormal"><span style="font-size:9.5pt"><img border="0" src="https://ssl.gstatic.com/ui/v1/icons/mail/images/cleardot.gif"><u></u><u></u></span></p>
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<p class="MsoNormal"><u></u> <u></u></p>
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<p class="MsoNormal">-- <u></u><u></u></p>
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<div>
<p class="MsoNormal">Maya D'Alessio <u></u><u></u></p>
<div>
<p class="MsoNormal">PhD student<u></u><u></u></p>
</div>
<div>
<p class="MsoNormal">B1 377B, x32320<u></u><u></u></p>
</div>
<div>
<p class="MsoNormal">Graduate Studies Endowment Fund Coordinator<u></u><u></u></p>
</div>
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<p class="MsoNormal">Biology GSA Vice Chair<u></u><u></u></p>
</div>
<div>
<p class="MsoNormal">GSA Director At-Large<u></u><u></u></p>
</div>
<div>
<p class="MsoNormal">University of Waterloo<u></u><u></u></p>
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<p class="MsoNormal"><u></u> <u></u></p>
</blockquote>
<p class="MsoNormal"><u></u> <u></u></p>
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<p class="MsoNormal" style="margin-bottom:12.0pt"><br>
_______________________________________________<br>
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<p class="MsoNormal"><br>
<br clear="all">
<u></u><u></u></p>
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<p class="MsoNormal"><u></u> <u></u></p>
</div>
<p class="MsoNormal">-- <u></u><u></u></p>
<div>
<div>
<p class="MsoNormal">Maya D'Alessio<u></u><u></u></p>
<div>
<p class="MsoNormal">PhD student<u></u><u></u></p>
</div>
<div>
<p class="MsoNormal">B1 377B, x32320<u></u><u></u></p>
</div>
<div>
<p class="MsoNormal">Graduate Studies Endowment Fund Coordinator<u></u><u></u></p>
</div>
<div>
<p class="MsoNormal">Biology GSA Vice Chair<u></u><u></u></p>
</div>
<div>
<p class="MsoNormal">GSA Director At-Large<u></u><u></u></p>
</div>
<div>
<p class="MsoNormal">University of Waterloo<u></u><u></u></p>
</div>
</div>
</div>
</div>
</div></div></div>
</div>
<br>_______________________________________________<br>
Felvtalk mailing list<br>
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<br></blockquote></div><br><br clear="all"><div><br></div>-- <br><div class="gmail_signature"><div dir="ltr">Maya D'Alessio<div>PhD student</div><div>B1 377B, x32320</div><div>Graduate Studies Endowment Fund Coordinator</div><div>Biology GSA Vice Chair</div><div>GSA Director At-Large</div><div>University of Waterloo</div></div></div>
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