From Wendy at WendyFrank.Net Thu Sep 19 00:26:00 2019 From: Wendy at WendyFrank.Net (Wendy) Date: Thu, 19 Sep 2019 05:26:00 +0000 Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT Message-ID: Hello, Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. Would you please let us know what we can do to help our much-loved cat? A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work that are not in normal range: AST (SGOT) 106 Glucose 178 CPK 711 WBC 20.5 RBC 2.5 HGB 4.5 HCT 14 NRBC 9 Platelet Count 78 Neutrophils 1640 Lymphocytes 17630 Monocytes 1025 Basophils 205 Protein 2+ Reticulocyte 0.6 and 15000 Would you please let us know what we can do to help our cat? Thank you, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: From Wendy at WendyFrank.Net Thu Sep 19 01:02:55 2019 From: Wendy at WendyFrank.Net (Wendy) Date: Thu, 19 Sep 2019 06:02:55 +0000 Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT - REPOSTING WITH FULL BLOOD WORK Message-ID: <6b18bd2f7bd344f0bc54becf0572422d@WendyFrank.Net> Hello, Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. Would you please let us know what we can do to help our much-loved cat? A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work: Tests Results Ref. Range Units Total Protein 6.1 5.2- 8.8 g/dL Albumin 3.5 2.5- 3.9 g/dl Globulin 2.6 2.3- 5.3 g/dL A/G Rat io 1.3 0.35- 1.5 AST (SGOT) 106 (HIGH) 10-100 IU/L ALT (SGPT) 39 10- 100 IU/L Alk Phosphatase 40 6- 102 IU/L GGT 1 1- 10 IU/L Total Bilirubin 0.1 0.1- 0.4 mg/dL BUN 15 14- 36 mg/dl Creatinine 0.9 0.6- 2.4 mg/dl BUN/Creatinine Ratio 17 4-33 Phosphorus 4.4 2.4- 8.2 mg/dl Glucose 178 (HIGH) 64 - 170 mg/dL Calcium 9.3 8.2- 10 .8 m g/dL Magnesium 2.0 1.5- 2.5 mEq/L Sodium 153 145-158 mEq/L Potassium 4.6 3.4- 5.6 mEq/L NAIK Ratio 33 32-41 Chloride 121 104-128 mEq/L Cholesterol 94 75- 220 mg/dl Triglyceride 108 25-160 mg/dl Amylase 611 100-1200 IU/L PrecisionPSL(tm) 10 8- 26 U/L Acute pancrea titis is unlikely. Chronic pancreatitis is not excluded by a norm al PrecisionPSL(tm). CPK 711 (HIGH) 56-529 IU/L WBC 20.5 (HIGH) 3.5- 16.0 10'/?L Corrected for NRBCs ABC 2.5 (LOW) 5.92-9.93 10?/? L HGB 4.5 (LOW) 9.3- 15 .9 g/dL HCT 29-48 % ' The hematocrit in th 27. (Normal range 29-48). A recent study has indicated that >23% of anemic cats are infected with one or more species of hemoplasma and several studies confirm that PCR is significantly more sensitive in detecting hemoplasma. MCV 57 37-61 fl MCH 18.2 11-21 pg MCHC 32 30-38 g/dl Poikilocytosis Slight NRBC 9(HIGH) 0-1 /100 WBC Blood Parasites None Seen RBC Comment Rouleaux Moderate Platelet Count 78 (LOW) 200-500 10'/?L Platelet count reflects the minimum number due to platelet clumping. Platelet Estimate Adequate Differential Absolute o/o Neutrophils (LOW) 1640 8 2500 - 8500 /?L Bands 0 Lymphocytes (HIGH) 17630 86 1200 - 8000 /?L Monocytes (HIGH) 1025 5 0-600 /? L Eosinophils 0 0 0-1000 /? L Basophils (HIGH) 205 1 0- 150 /?L FREE T4 BY EQU ILIBRIUM D IALYS IS (Pending) UR INALYSIS- C OMPL ETE Collection Method Cystocentesis 0.8- 4.0 ? g/dl Color Appearance Spec ific Gravity pH DARK YELLOW TURBID 1.056 1.015- 1.060 7.0 5.5- 7.0 Protein 2+ (HIGH) NEGATIVE Urine protein:creatini ne ratio testing is recommended (if the sediment is inactive) to he lp determine the clinical significance of proteinuria. Glucose-Strip NEGATIVE NEGATIVE Ketones NEGATIVE NEGATIVE Bilirubin NEGATIVE NEGATIVE Occult Blood NEGATIVE NEGATIVE WBC NONE 0-3 HPF RBC NONE 0-3 HPF Casts NONE SEEN Hyaline 0-3 LPF Crystals NONE SEEN HPF Bacteria Epithelial Cells NONE SEEN NONE SEEN None Seen HPF HPF Fat Droplets >50 HPF RETICULOCYTE COUNT REFLEX Reticulocyte Total Abso lute Ret iculocytes 0.6 0-1 % 15000 <45,000 J?L Would you please let us know what we can do to help our cat? Thank you, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Thu Sep 19 06:32:40 2019 From: johnston1110 at comcast.net (LORRAINE JOHNSTON) Date: Thu, 19 Sep 2019 07:32:40 -0400 (EDT) Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT - REPOSTING WITH FULL BLOOD WORK In-Reply-To: <6b18bd2f7bd344f0bc54becf0572422d@WendyFrank.Net> References: <6b18bd2f7bd344f0bc54becf0572422d@WendyFrank.Net> Message-ID: <818926190.47189.1568892760890@connect.xfinity.com> You are using feline interferon omega, yes? Not human interferon? The human version can be given orally for stomatitis but if injected it will eventually cause an allergic reaction. - Lorraine > On September 19, 2019 at 2:02 AM Wendy wrote: > > > Hello, Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. Would you please let us know what we can do to help our much-loved cat? A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work: > > Tests Results Ref. Range Units > > Total Protein 6.1 5.2- 8.8 g/dL > > Albumin 3.5 2.5- 3.9 g/dl > > Globulin 2.6 2.3- 5.3 g/dL > > A/G Rat io 1.3 0.35- 1.5 > > AST (SGOT) 106 (HIGH) 10-100 IU/L > > ALT (SGPT) 39 10- 100 IU/L > > Alk Phosphatase 40 6- 102 IU/L > > GGT 1 1- 10 IU/L > > Total Bilirubin 0.1 0.1- 0.4 mg/dL > > BUN 15 14- 36 mg/dl > > Creatinine 0.9 0.6- 2.4 mg/dl > > BUN/Creatinine Ratio 17 4-33 > > Phosphorus 4.4 2.4- 8.2 mg/dl > > Glucose 178 (HIGH) 64 - 170 mg/dL > > > Calcium 9.3 8.2- 10 .8 m g/dL > > Magnesium 2.0 1.5- 2.5 mEq/L > > Sodium 153 145-158 mEq/L > > Potassium 4.6 3.4- 5.6 mEq/L > > NAIK Ratio 33 32-41 > > Chloride 121 104-128 mEq/L > > Cholesterol 94 75- 220 mg/dl > > Triglyceride 108 25-160 mg/dl > > Amylase 611 100-1200 IU/L > > PrecisionPSL? 10 8- 26 U/L Acute pancrea titis is unlikely. Chronic pancreatitis is not excluded > > by a norm al PrecisionPSL?. > > > > CPK 711 (HIGH) 56-529 IU/L > > > > WBC 20.5 (HIGH) 3.5- 16.0 10'/?L > > Corrected for NRBCs > > > ABC 2.5 (LOW) 5.92-9.93 10?/? L > > HGB 4.5 (LOW) 9.3- 15 .9 g/dL > > HCT 29-48 % ' > > The hematocrit in th 27. (Normal range 29-48). A recent study has indicated that >23% of anemic cats are infected with one or more species of hemoplasma and several studies confirm that PCR is significantly more sensitive in detecting hemoplasma. > > > MCV 57 37-61 fl > > MCH 18.2 11-21 pg > > MCHC 32 30-38 g/dl > > Poikilocytosis Slight > > NRBC 9(HIGH) 0-1 /100 WBC > > Blood Parasites None Seen RBC Comment > > Rouleaux Moderate > > > Platelet Count 78 (LOW) 200-500 10'/?L > > Platelet count reflects the minimum number due to platelet clumping. > > > Platelet Estimate Adequate > > Differential Absolute o/o > > Neutrophils (LOW) 1640 8 2500 - 8500 /?L > > Bands 0 > > Lymphocytes (HIGH) 17630 86 1200 - 8000 /?L > > Monocytes (HIGH) 1025 5 0-600 /? L > > Eosinophils 0 0 0-1000 /? L > > Basophils (HIGH) 205 1 0- 150 /?L > > > FREE T4 BY EQU ILIBRIUM D IALYS IS (Pending) > > UR INALYSIS- C OMPL ETE > > Collection Method Cystocentesis > > > 0.8- 4.0 ? g/dl > > > > > > Color Appearance Spec ific Gravity pH > > > DARK YELLOW TURBID > > 1.056 1.015- 1.060 > > 7.0 5.5- 7.0 > > > > Protein > > > > 2+ (HIGH) > > NEGATIVE > > Urine protein:creatini ne ratio testing is recommended (if the sediment is inactive) to he lp determine the clinical significance of proteinuria. > > > Glucose-Strip > > NEGATIVE > > NEGATIVE > > > > Ketones > > NEGATIVE > > NEGATIVE > > Bilirubin > > NEGATIVE > > NEGATIVE > > Occult Blood > > NEGATIVE > > NEGATIVE > > WBC > > NONE > > 0-3 > > HPF > > RBC > > NONE > > 0-3 > > HPF > > Casts > > NONE SEEN > > Hyaline 0-3 > > LPF > > Crystals > > NONE SEEN > > > > HPF > > Bacteria Epithelial Cells > > NONE SEEN NONE SEEN > > None Seen > > HPF HPF > > Fat Droplets > > >50 > > > > HPF > > > RETICULOCYTE COUNT REFLEX > > Reticulocyte Total Abso lute Ret iculocytes > > > > 0.6 0-1 % > > 15000 <45,000 J?L > > > > Would you please let us know what we can do to help our cat? > > Thank you, Wendy > > > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From Wendy at WendyFrank.Net Thu Sep 19 06:41:54 2019 From: Wendy at WendyFrank.Net (Wendy) Date: Thu, 19 Sep 2019 11:41:54 +0000 Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT Message-ID: <6E2D8250-A10E-41EF-9004-D2702C4482E3@WendyFrank.Net> Hello Lorraine, it is interferon alpha 2B compounded that my vet ordered for our cat from Road Runner Pharmacy. It shows Cat on the label. Does this help? Thank you so much, Wendy On Sep 18, 2019, at 10:26 PM, Wendy > wrote: Hello, Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. Would you please let us know what we can do to help our much-loved cat? A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work that are not in normal range: AST (SGOT) 106 Glucose 178 CPK 711 WBC 20.5 RBC 2.5 HGB 4.5 HCT 14 NRBC 9 Platelet Count 78 Neutrophils 1640 Lymphocytes 17630 Monocytes 1025 Basophils 205 Protein 2+ Reticulocyte 0.6 and 15000 Would you please let us know what we can do to help our cat? Thank you, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: From Wendy at WendyFrank.Net Thu Sep 19 06:42:56 2019 From: Wendy at WendyFrank.Net (Wendy) Date: Thu, 19 Sep 2019 11:42:56 +0000 Subject: [Felvtalk] Felvtalk Digest, Vol 57, Issue 1 In-Reply-To: References: Message-ID: <82A92642-4157-49A4-AF38-6234F658237A@WendyFrank.Net> Hello Lorraine, it is interferon alpha 2B compounded that my vet ordered for our cat from Road Runner Pharmacy. It shows Cat on the label. Does this help? Thank you so much, Wendy > On Sep 18, 2019, at 11:03 PM, "felvtalk-request at felineleukemia.org" wrote: > > Send Felvtalk mailing list submissions to > felvtalk at felineleukemia.org > > To subscribe or unsubscribe via the World Wide Web, visit > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > or, via email, send a message with subject or body 'help' to > felvtalk-request at felineleukemia.org > > You can reach the person managing the list at > felvtalk-owner at felineleukemia.org > > When replying, please edit your Subject line so it is more specific > than "Re: Contents of Felvtalk digest..." > Today's Topics: > > 1. PLEASE HELP ASAP - VERY SICK FELV CAT (Wendy) > 2. PLEASE HELP ASAP - VERY SICK FELV CAT - REPOSTING WITH FULL > BLOOD WORK (Wendy) > > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org From Wendy at WendyFrank.Net Thu Sep 19 06:50:19 2019 From: Wendy at WendyFrank.Net (Wendy) Date: Thu, 19 Sep 2019 11:50:19 +0000 Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT Message-ID: Hello Lorraine, it is interferon alpha 2B compounded that my vet ordered for our cat from Road Runner Pharmacy. It shows Cat on the label. He takes the interferon orally, and not by injection. Sorry for all of the responses, I?m trying to figure out this system and worried about our precious cat. Does this help? Thank you so much, Wendy On Sep 18, 2019, at 10:26 PM, Wendy > wrote: Hello, Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. Would you please let us know what we can do to help our much-loved cat? A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work that are not in normal range: AST (SGOT) 106 Glucose 178 CPK 711 WBC 20.5 RBC 2.5 HGB 4.5 HCT 14 NRBC 9 Platelet Count 78 Neutrophils 1640 Lymphocytes 17630 Monocytes 1025 Basophils 205 Protein 2+ Reticulocyte 0.6 and 15000 Would you please let us know what we can do to help our cat? Thank you, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: From Wendy at WendyFrank.Net Thu Sep 19 06:57:45 2019 From: Wendy at WendyFrank.Net (Wendy) Date: Thu, 19 Sep 2019 11:57:45 +0000 Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT Message-ID: <85852685-AF77-4C6F-91AC-55488959072D@WendyFrank.Net> He is getting the interferon orally and it is never being injected. On Sep 18, 2019, at 10:26 PM, Wendy > wrote: Hello, Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. Would you please let us know what we can do to help our much-loved cat? A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work that are not in normal range: AST (SGOT) 106 Glucose 178 CPK 711 WBC 20.5 RBC 2.5 HGB 4.5 HCT 14 NRBC 9 Platelet Count 78 Neutrophils 1640 Lymphocytes 17630 Monocytes 1025 Basophils 205 Protein 2+ Reticulocyte 0.6 and 15000 Would you please let us know what we can do to help our cat? Thank you, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Thu Sep 19 07:01:32 2019 From: johnston1110 at comcast.net (LORRAINE JOHNSTON) Date: Thu, 19 Sep 2019 08:01:32 -0400 (EDT) Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT In-Reply-To: References: Message-ID: <1487132338.47744.1568894492213@connect.xfinity.com> Oral dosing is okay with human interferon Alfa 2b. You might want to try retromad1, imported from Malaysia. There is a man, John B., on the fivtherapy yahoogroup who has a colony of felv and fiv cats, and lots of good advice. You might want to join that group (felv is discussed there, even though the group name is fivtherapy). Also, I will get in touch with John via private email about your kitty. He is in South Africa, so if you?re in the US, there might be a time delay. BTW, I don?t hear too many success stories about tcyte. Not that it causes harm, to my knowledge, just that it doesn't seem to help. - Lorraine > On September 19, 2019 at 7:50 AM Wendy wrote: > > > Hello Lorraine, it is interferon alpha 2B compounded that my vet ordered for our cat from Road Runner Pharmacy. It shows Cat on the label. He takes the interferon orally, and not by injection. Sorry for all of the responses, I?m trying to figure out this system and worried about our precious cat. Does this help? Thank you so much, Wendy > > On Sep 18, 2019, at 10:26 PM, Wendy < Wendy at wendyfrank.net mailto:Wendy at wendyfrank.net > wrote: > > > > > > > Hello, Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. Would you please let us know what we can do to help our much-loved cat? A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work that are not in normal range: > > > > AST (SGOT) 106 > > > > Glucose 178 > > > > CPK 711 > > > > WBC 20.5 > > > > RBC 2.5 > > > > HGB 4.5 > > > > HCT 14 > > > > NRBC 9 > > > > Platelet Count 78 > > > > Neutrophils 1640 > > > > Lymphocytes 17630 > > > > Monocytes 1025 > > > > Basophils 205 > > > > Protein 2+ > > > > Reticulocyte 0.6 and 15000 > > > > Would you please let us know what we can do to help our cat? > > > > Thank you, Wendy > > > > > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From Wendy at WendyFrank.Net Thu Sep 19 09:08:06 2019 From: Wendy at WendyFrank.Net (Wendy) Date: Thu, 19 Sep 2019 14:08:06 +0000 Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT - reposting as other email too long Message-ID: <6E95EE96-E5A1-4395-BDF1-98A94C8AEC74@WendyFrank.Net> Hello, Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. Would you please let us know what we can do to help our much-loved cat? A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work that are not in normal range: AST (SGOT) 106 Glucose 178 CPK 711 WBC 20.5 RBC 2.5 HGB 4.5 HCT 14 NRBC 9 Platelet Count 78 Neutrophils 1640 Lymphocytes 17630 Monocytes 1025 Basophils 205 Protein 2+ Reticulocyte 0.6 and 15000 Would you please let us know what we can do to help our cat? Thank you, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: From gidget43 at aol.com Thu Sep 19 10:16:46 2019 From: gidget43 at aol.com (gidget43 at aol.com) Date: Thu, 19 Sep 2019 15:16:46 +0000 (UTC) Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT - reposting as other email too long References: <1814683036.6617264.1568906206116.ref@mail.yahoo.com> Message-ID: <1814683036.6617264.1568906206116@mail.yahoo.com> I very seldom post here, but your baby is very anemic.? HCT 14% and if it continues to drop will need a transfusion.? Many here at one time suggested Winstrol for anemia.??https://www.rxlist.com/winstrol-side-effects-drug-center.htm? ? I am sure others will chime in here, but this was said to work.??https://gainsmadness.com/what-is-winstrol-cycle/ -----Original Message----- From: Wendy To: felvtalk at felineleukemia.org Sent: Thu, Sep 19, 2019 10:08 am Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT - reposting as other email too long <!-- #yiv9841986119 _filtered #yiv9841986119 {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4;} _filtered #yiv9841986119 {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4;} #yiv9841986119 #yiv9841986119 p.yiv9841986119MsoNormal, #yiv9841986119 li.yiv9841986119MsoNormal, #yiv9841986119 div.yiv9841986119MsoNormal {margin:0in; margin-bottom:.0001pt; font-size:11.0pt; font-family:"Calibri", sans-serif;} #yiv9841986119 a:link, #yiv9841986119 span.yiv9841986119MsoHyperlink { color:#0563C1; text-decoration:underline;} #yiv9841986119 a:visited, #yiv9841986119 span.yiv9841986119MsoHyperlinkFollowed { color:#954F72; text-decoration:underline;} #yiv9841986119 span.yiv9841986119EmailStyle17 { font-family:"Calibri", sans-serif; color:windowtext;} #yiv9841986119 .yiv9841986119MsoChpDefault { font-family:"Calibri", sans-serif;} _filtered #yiv9841986119 { margin:1.0in 1.0in 1.0in 1.0in;} #yiv9841986119 div.yiv9841986119WordSection1 {} -->Hello, Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly.? He is a house cat, and he was neutered in May of 2019.? Would you please let us know what we can do to help our much-loved cat?? A few days ago, he became lethargic and lost interest in eating.? We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow.? We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. ?As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive.? Since October 2018, we cured him of giardia and bartonella henselae.? On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time.? In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated.? We have continued the interferon and t-cyte in this manner ever since 03/2019.? Just yesterday, here are the results of his blood work that are not in normal range: AST (SGOT) 106 Glucose 178 CPK 711 WBC 20.5 RBC 2.5 HGB 4.5 HCT 14 NRBC 9 Platelet Count 78 Neutrophils 1640 Lymphocytes 17630 Monocytes 1025 Basophils 205 Protein 2+ Reticulocyte 0.6 and 15000 Would you please let us know what we can do to help our cat? Thank you, Wendy _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From aoakley at oakleylegal.com Thu Sep 19 15:50:19 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Thu, 19 Sep 2019 20:50:19 +0000 Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT In-Reply-To: References: Message-ID: <80edcbd55e3a436c8ade62c6517ee68e@OAKSERVER.oakley.local> As others have mentioned in reply to your post, I have used a combination of Winstrol (Stanozolol), Doxycycline and Prednisone. The blood work seems to show that there is an affect on both the red cell lines and platelets. That suggests that this is a bone marrow depression, and in turn that suggests that this is likely the effect of FeLV. My experience has been that the Winstrol seems to turn back on or encourage the growth of new bone marrow cells, and is really great for increasing red cell indices (red cell counts, haematocrit, haemoglobin, reticulocyte count), and I saw it take effect pretty quickly. My cat's haematocrit was down to 10 after two separate rounds of blood transfusion. By the way, I don't understand the explanation in your email, that you've been told that the blood transfusion wasn't effective because of too much IV fluids. That doesn't make a lot of sense. You are still infusing the same volume of red cells, whether that is diluted by the IV fluids or not. I agree that the lab results may show a dilution effect because of the IV fluids, but that just means that when the excess fluid is pee'd out, then the haematocrit result will go up. By the way, if there is truly a dilution effect, it will show on a number of lab results like sodium, potassium, urea and platelets. What I had my cat on was: Winstrol (stanozolol) 1 mg, 2 times a day (though this can be dramatically increased if necessary) Doxycycline 50 mg daily (can be given once, or split to 25 mg, 2 times a day) Prednisone/Prednisolone 5 mg daily (can be given once, or split to 2.5 mg, 2 times a day) Amani From: Felvtalk On Behalf Of Wendy Sent: September 19, 2019 1:26 AM To: felvtalk at felineleukemia.org Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT Importance: High Hello, Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. Would you please let us know what we can do to help our much-loved cat? A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work that are not in normal range: AST (SGOT) 106 Glucose 178 CPK 711 WBC 20.5 RBC 2.5 HGB 4.5 HCT 14 NRBC 9 Platelet Count 78 Neutrophils 1640 Lymphocytes 17630 Monocytes 1025 Basophils 205 Protein 2+ Reticulocyte 0.6 and 15000 Would you please let us know what we can do to help our cat? Thank you, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: From Wendy at WendyFrank.Net Thu Sep 19 21:41:25 2019 From: Wendy at WendyFrank.Net (Wendy) Date: Fri, 20 Sep 2019 02:41:25 +0000 Subject: [Felvtalk] Bone Marrow Testing for FELV positive Cat? Message-ID: Hello, Thank you all for your replies earlier today. Our cats' red count is coming back after 2 blood transfusions, and we started doxy today. He is eating, drinking, purring, has much better energy, is back to talking, etc. We are awaiting results that we should have tomorrow morning on the test of his lymphocytes using blood that was drawn before the blood transfusions. If the test comes back showing that the lymphocytes contain cancer cells, then we have our answer. If the test comes back showing that the lymphocytes do not contain cancer cells, then it has been suggested that we do bone marrow testing asap tomorrow afternoon. My understanding is that the bone marrow test would likely either show that he has myelodysplasia or cancer in his bone marrow. My question is: Would the suggested treatment of Doxy + Pred + Winstrol change if we find out that our cat has myelodysplasia vs if he has cancer in his bone marrow? If the treatment is the same, then I question putting our cat at the risk of anesthesia, lowering his red count, infection, etc. The plan is to start our cat on Doxy + Pred + Winstrol tomorrow afternoon, and we are being told that if we want to test his bone marrow we need to do it tomorrow morning before we start giving him steroids. In addition, his chest x-ray today was clean, and his abdominal ultrasound showed a slightly enlarge spleen and either a few slightly enlarged lymph nodes or possibly a few small satellite spleens, all of which seems can be expected with the anemia and / or infection, and therefore was not cause for concern. Following are the background facts, which I also posted this morning: Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work: Tests Results Ref. Range Total Protein 6.1 5.2- 8.8 g/dL Albumin 3.5 2.5- 3.9 g/dl Globulin 2.6 2.3- 5.3 g/dL A/G Ratio 1.3 0.35- 1.5 AST (SGOT) 106 (HIGH) 10-100 IU/L ALT (SGPT) 39 10- 100 IU/L Alk Phosphatase 40 6- 102 IU/L GGT 1 1- 10 IU/L Total Bilirubin 0.1 0.1- 0.4 mg/dL BUN 15 14- 36 mg/dl Creatinine 0.9 0.6- 2.4 mg/dl BUN/Creatinine Ratio 17 4-33 Phosphorus 4.4 2.4- 8.2 mg/dl Glucose 178 (HIGH) 64 - 170 mg/dL Calcium 9.3 8.2- 10 .8 mg/dL Magnesium 2.0 1.5- 2.5 mEq/L Sodium 153 145-158 mEq/L Potassium 4.6 3.4- 5.6 mEq/L NAIK Ratio 33 32-41 Chloride 121 104-128 mEq/L Cholesterol 94 75- 220 mg/dl Triglyceride 108 25-160 mg/dl Amylase 611 100-1200 IU/L PrecisionPSL(tm) 10 8- 26 U/L Acute pancreatitis is unlikely. Chronic pancreatitis is not excluded. CPK 711 (HIGH) 56-529 IU/L WBC 20.5 (HIGH) 3.5- 16.0 10'/?L Corrected for NRBCs ABC 2.5 (LOW) 5.92-9.93 10?/? L HGB 4.5 (LOW) 9.3- 15 .9 g/dL HCT 29-48 % ' The hematocrit in th 27. (Normal range 29-48). A recent study has indicated that >23% of anemic cats are infected with one or more species of hemoplasma and several studies confirm that PCR is significantly more sensitive in detecting hemoplasma. MCV 57 37-61 fl MCH 18.2 11-21 pg MCHC 32 30-38 g/dl Poikilocytosis Slight NRBC 9(HIGH) 0-1/100 WBC Blood Parasites None Seen RBC Comment Rouleaux Moderate Platelet Count 78 (LOW) 200-500 10'/?L Platelet count reflects the minimum number due to platelet clumping. Platelet Estimate Adequate Differential Absolute o/o Neutrophils (LOW) 1640 8 2500 - 8500 /?L Bands 0 Lymphocytes (HIGH) 17630 86 1200 - 8000 /?L Monocytes (HIGH) 1025 5 0-600 /? L Eosinophils 0 0 0-1000 /? L Basophils (HIGH) 205 1 0- 150 /?L FREE T4 BY EQU ILIBRIUM D IALYS IS (Pending) UR INALYSIS- C OMPL ETE Collection Method Cystocentesis 0.8- 4.0 ? g/dl Color Appearance Specific Gravity pH DARK YELLOW TURBID 1.056 1.015- 1.060 7.0 5.5- 7.0 Protein 2+ (HIGH) NEGATIVE Glucose-Strip NEGATIVE NEGATIVE Ketones NEGATIVE NEGATIVE Bilirubin NEGATIVE NEGATIVE Occult Blood NEGATIVE NEGATIVE WBC NONE 0-3 HPF RBC NONE 0-3 HPF Casts NONE SEEN Hyaline 0-3 LPF Crystals NONE SEEN HPF Bacteria Epithelial Cells NONE SEEN NONE SEEN None Seen HPF HPF Fat Droplets >50 HPF RETICULOCYTE COUNT REFLEX Reticulocyte Total Abso lute Ret iculocytes 0.6 0-1 % 15000 <45,000 J?L Would you please let us know what we can do to help our cat? Thank you again, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: From Wendy at WendyFrank.Net Thu Sep 19 21:45:05 2019 From: Wendy at WendyFrank.Net (Wendy) Date: Fri, 20 Sep 2019 02:45:05 +0000 Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT In-Reply-To: <80edcbd55e3a436c8ade62c6517ee68e@OAKSERVER.oakley.local> References: <80edcbd55e3a436c8ade62c6517ee68e@OAKSERVER.oakley.local> Message-ID: <66ec516d12d94518a7731124a340e65b@WendyFrank.Net> Hello Amani, Thank you very much for your detailed response. I apologize for my poor explanation regarding the blood transfusion not being effective. You are correct, that it was merely a dilution effect from the iv fluids. All the best, Wendy From: Amani Oakley Sent: Thursday, September 19, 2019 1:50 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT As others have mentioned in reply to your post, I have used a combination of Winstrol (Stanozolol), Doxycycline and Prednisone. The blood work seems to show that there is an affect on both the red cell lines and platelets. That suggests that this is a bone marrow depression, and in turn that suggests that this is likely the effect of FeLV. My experience has been that the Winstrol seems to turn back on or encourage the growth of new bone marrow cells, and is really great for increasing red cell indices (red cell counts, haematocrit, haemoglobin, reticulocyte count), and I saw it take effect pretty quickly. My cat's haematocrit was down to 10 after two separate rounds of blood transfusion. By the way, I don't understand the explanation in your email, that you've been told that the blood transfusion wasn't effective because of too much IV fluids. That doesn't make a lot of sense. You are still infusing the same volume of red cells, whether that is diluted by the IV fluids or not. I agree that the lab results may show a dilution effect because of the IV fluids, but that just means that when the excess fluid is pee'd out, then the haematocrit result will go up. By the way, if there is truly a dilution effect, it will show on a number of lab results like sodium, potassium, urea and platelets. What I had my cat on was: Winstrol (stanozolol) 1 mg, 2 times a day (though this can be dramatically increased if necessary) Doxycycline 50 mg daily (can be given once, or split to 25 mg, 2 times a day) Prednisone/Prednisolone 5 mg daily (can be given once, or split to 2.5 mg, 2 times a day) Amani From: Felvtalk > On Behalf Of Wendy Sent: September 19, 2019 1:26 AM To: felvtalk at felineleukemia.org Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT Importance: High Hello, Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. Would you please let us know what we can do to help our much-loved cat? A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work that are not in normal range: AST (SGOT) 106 Glucose 178 CPK 711 WBC 20.5 RBC 2.5 HGB 4.5 HCT 14 NRBC 9 Platelet Count 78 Neutrophils 1640 Lymphocytes 17630 Monocytes 1025 Basophils 205 Protein 2+ Reticulocyte 0.6 and 15000 Would you please let us know what we can do to help our cat? Thank you, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: From aoakley at oakleylegal.com Thu Sep 19 22:13:35 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Fri, 20 Sep 2019 03:13:35 +0000 Subject: [Felvtalk] Bone Marrow Testing for FELV positive Cat? In-Reply-To: References: Message-ID: Wendy I was going to comment on that issue earlier, but I thought you had already gone ahead with the bone marrow testing. I am not sure there is any other treatment, regardless of the outcome of the testing. I personally agree with you that I probably would choose not to put my cat through bone marrow testing, when it really can't affect the outcome. I am glad to hear that he is feeling better after the two transfusions. Use the Doxy-Pred-Winstrol combination now, and hopefully, your kitten's haematocrit doesn't end up falling after the temporary boost from the blood transfusion. The life span of a red blood cell is 120 days (at least in humans), and the blood transfusions will have red cells at different stages of their life spans, so you probably already know that the effect of the transfusions will probably only last 3 months or so. Hopefully by then the Winstrol would have kicked in to assist the bone marrow in producing red cells. Amani From: Felvtalk On Behalf Of Wendy Sent: September 19, 2019 10:41 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Bone Marrow Testing for FELV positive Cat? Hello, Thank you all for your replies earlier today. Our cats' red count is coming back after 2 blood transfusions, and we started doxy today. He is eating, drinking, purring, has much better energy, is back to talking, etc. We are awaiting results that we should have tomorrow morning on the test of his lymphocytes using blood that was drawn before the blood transfusions. If the test comes back showing that the lymphocytes contain cancer cells, then we have our answer. If the test comes back showing that the lymphocytes do not contain cancer cells, then it has been suggested that we do bone marrow testing asap tomorrow afternoon. My understanding is that the bone marrow test would likely either show that he has myelodysplasia or cancer in his bone marrow. My question is: Would the suggested treatment of Doxy + Pred + Winstrol change if we find out that our cat has myelodysplasia vs if he has cancer in his bone marrow? If the treatment is the same, then I question putting our cat at the risk of anesthesia, lowering his red count, infection, etc. The plan is to start our cat on Doxy + Pred + Winstrol tomorrow afternoon, and we are being told that if we want to test his bone marrow we need to do it tomorrow morning before we start giving him steroids. In addition, his chest x-ray today was clean, and his abdominal ultrasound showed a slightly enlarge spleen and either a few slightly enlarged lymph nodes or possibly a few small satellite spleens, all of which seems can be expected with the anemia and / or infection, and therefore was not cause for concern. Following are the background facts, which I also posted this morning: Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work: Tests Results Ref. Range Total Protein 6.1 5.2- 8.8 g/dL Albumin 3.5 2.5- 3.9 g/dl Globulin 2.6 2.3- 5.3 g/dL A/G Ratio 1.3 0.35- 1.5 AST (SGOT) 106 (HIGH) 10-100 IU/L ALT (SGPT) 39 10- 100 IU/L Alk Phosphatase 40 6- 102 IU/L GGT 1 1- 10 IU/L Total Bilirubin 0.1 0.1- 0.4 mg/dL BUN 15 14- 36 mg/dl Creatinine 0.9 0.6- 2.4 mg/dl BUN/Creatinine Ratio 17 4-33 Phosphorus 4.4 2.4- 8.2 mg/dl Glucose 178 (HIGH) 64 - 170 mg/dL Calcium 9.3 8.2- 10 .8 mg/dL Magnesium 2.0 1.5- 2.5 mEq/L Sodium 153 145-158 mEq/L Potassium 4.6 3.4- 5.6 mEq/L NAIK Ratio 33 32-41 Chloride 121 104-128 mEq/L Cholesterol 94 75- 220 mg/dl Triglyceride 108 25-160 mg/dl Amylase 611 100-1200 IU/L PrecisionPSL(tm) 10 8- 26 U/L Acute pancreatitis is unlikely. Chronic pancreatitis is not excluded. CPK 711 (HIGH) 56-529 IU/L WBC 20.5 (HIGH) 3.5- 16.0 10'/?L Corrected for NRBCs ABC 2.5 (LOW) 5.92-9.93 10?/? L HGB 4.5 (LOW) 9.3- 15 .9 g/dL HCT 29-48 % ' The hematocrit in th 27. (Normal range 29-48). A recent study has indicated that >23% of anemic cats are infected with one or more species of hemoplasma and several studies confirm that PCR is significantly more sensitive in detecting hemoplasma. MCV 57 37-61 fl MCH 18.2 11-21 pg MCHC 32 30-38 g/dl Poikilocytosis Slight NRBC 9(HIGH) 0-1/100 WBC Blood Parasites None Seen RBC Comment Rouleaux Moderate Platelet Count 78 (LOW) 200-500 10'/?L Platelet count reflects the minimum number due to platelet clumping. Platelet Estimate Adequate Differential Absolute o/o Neutrophils (LOW) 1640 8 2500 - 8500 /?L Bands 0 Lymphocytes (HIGH) 17630 86 1200 - 8000 /?L Monocytes (HIGH) 1025 5 0-600 /? L Eosinophils 0 0 0-1000 /? L Basophils (HIGH) 205 1 0- 150 /?L FREE T4 BY EQU ILIBRIUM D IALYS IS (Pending) UR INALYSIS- C OMPL ETE Collection Method Cystocentesis 0.8- 4.0 ? g/dl Color Appearance Specific Gravity pH DARK YELLOW TURBID 1.056 1.015- 1.060 7.0 5.5- 7.0 Protein 2+ (HIGH) NEGATIVE Glucose-Strip NEGATIVE NEGATIVE Ketones NEGATIVE NEGATIVE Bilirubin NEGATIVE NEGATIVE Occult Blood NEGATIVE NEGATIVE WBC NONE 0-3 HPF RBC NONE 0-3 HPF Casts NONE SEEN Hyaline 0-3 LPF Crystals NONE SEEN HPF Bacteria Epithelial Cells NONE SEEN NONE SEEN None Seen HPF HPF Fat Droplets >50 HPF RETICULOCYTE COUNT REFLEX Reticulocyte Total Abso lute Ret iculocytes 0.6 0-1 % 15000 <45,000 J?L Would you please let us know what we can do to help our cat? Thank you again, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: From Wendy at WendyFrank.Net Thu Sep 19 22:22:54 2019 From: Wendy at WendyFrank.Net (Wendy) Date: Fri, 20 Sep 2019 03:22:54 +0000 Subject: [Felvtalk] Bone Marrow Testing for FELV positive Cat? Message-ID: Thank you so much, again, Amani On Sep 19, 2019, at 8:13 PM, Amani Oakley > wrote: Wendy I was going to comment on that issue earlier, but I thought you had already gone ahead with the bone marrow testing. I am not sure there is any other treatment, regardless of the outcome of the testing. I personally agree with you that I probably would choose not to put my cat through bone marrow testing, when it really can?t affect the outcome. I am glad to hear that he is feeling better after the two transfusions. Use the Doxy-Pred-Winstrol combination now, and hopefully, your kitten?s haematocrit doesn?t end up falling after the temporary boost from the blood transfusion. The life span of a red blood cell is 120 days (at least in humans), and the blood transfusions will have red cells at different stages of their life spans, so you probably already know that the effect of the transfusions will probably only last 3 months or so. Hopefully by then the Winstrol would have kicked in to assist the bone marrow in producing red cells. Amani From: Felvtalk > On Behalf Of Wendy Sent: September 19, 2019 10:41 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Bone Marrow Testing for FELV positive Cat? Hello, Thank you all for your replies earlier today. Our cats? red count is coming back after 2 blood transfusions, and we started doxy today. He is eating, drinking, purring, has much better energy, is back to talking, etc. We are awaiting results that we should have tomorrow morning on the test of his lymphocytes using blood that was drawn before the blood transfusions. If the test comes back showing that the lymphocytes contain cancer cells, then we have our answer. If the test comes back showing that the lymphocytes do not contain cancer cells, then it has been suggested that we do bone marrow testing asap tomorrow afternoon. My understanding is that the bone marrow test would likely either show that he has myelodysplasia or cancer in his bone marrow. My question is: Would the suggested treatment of Doxy + Pred + Winstrol change if we find out that our cat has myelodysplasia vs if he has cancer in his bone marrow? If the treatment is the same, then I question putting our cat at the risk of anesthesia, lowering his red count, infection, etc. The plan is to start our cat on Doxy + Pred + Winstrol tomorrow afternoon, and we are being told that if we want to test his bone marrow we need to do it tomorrow morning before we start giving him steroids. In addition, his chest x-ray today was clean, and his abdominal ultrasound showed a slightly enlarge spleen and either a few slightly enlarged lymph nodes or possibly a few small satellite spleens, all of which seems can be expected with the anemia and / or infection, and therefore was not cause for concern. Following are the background facts, which I also posted this morning: Our FELV positive neutered male cat approximately 1 and ? years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work: Tests Results Ref. Range Total Protein 6.1 5.2- 8.8 g/dL Albumin 3.5 2.5- 3.9 g/dl Globulin 2.6 2.3- 5.3 g/dL A/G Ratio 1.3 0.35- 1.5 AST (SGOT) 106 (HIGH) 10-100 IU/L ALT (SGPT) 39 10- 100 IU/L Alk Phosphatase 40 6- 102 IU/L GGT 1 1- 10 IU/L Total Bilirubin 0.1 0.1- 0.4 mg/dL BUN 15 14- 36 mg/dl Creatinine 0.9 0.6- 2.4 mg/dl BUN/Creatinine Ratio 17 4-33 Phosphorus 4.4 2.4- 8.2 mg/dl Glucose 178 (HIGH) 64 - 170 mg/dL Calcium 9.3 8.2- 10 .8 mg/dL Magnesium 2.0 1.5- 2.5 mEq/L Sodium 153 145-158 mEq/L Potassium 4.6 3.4- 5.6 mEq/L NAIK Ratio 33 32-41 Chloride 121 104-128 mEq/L Cholesterol 94 75- 220 mg/dl Triglyceride 108 25-160 mg/dl Amylase 611 100-1200 IU/L PrecisionPSL? 10 8- 26 U/L Acute pancreatitis is unlikely. Chronic pancreatitis is not excluded. CPK 711 (HIGH) 56-529 IU/L WBC 20.5 (HIGH) 3.5- 16.0 10'/?L Corrected for NRBCs ABC 2.5 (LOW) 5.92-9.93 10?/? L HGB 4.5 (LOW) 9.3- 15 .9 g/dL HCT 29-48 % ' The hematocrit in th 27. (Normal range 29-48). A recent study has indicated that >23% of anemic cats are infected with one or more species of hemoplasma and several studies confirm that PCR is significantly more sensitive in detecting hemoplasma. MCV 57 37-61 fl MCH 18.2 11-21 pg MCHC 32 30-38 g/dl Poikilocytosis Slight NRBC 9(HIGH) 0-1/100 WBC Blood Parasites None Seen RBC Comment Rouleaux Moderate Platelet Count 78 (LOW) 200-500 10'/?L Platelet count reflects the minimum number due to platelet clumping. Platelet Estimate Adequate Differential Absolute o/o Neutrophils (LOW) 1640 8 2500 - 8500 /?L Bands 0 Lymphocytes (HIGH) 17630 86 1200 - 8000 /?L Monocytes (HIGH) 1025 5 0-600 /? L Eosinophils 0 0 0-1000 /? L Basophils (HIGH) 205 1 0- 150 /?L FREE T4 BY EQU ILIBRIUM D IALYS IS (Pending) UR INALYSIS- C OMPL ETE Collection Method Cystocentesis 0.8- 4.0 ? g/dl Color Appearance Specific Gravity pH DARK YELLOW TURBID 1.056 1.015- 1.060 7.0 5.5- 7.0 Protein 2+ (HIGH) NEGATIVE Glucose-Strip NEGATIVE NEGATIVE Ketones NEGATIVE NEGATIVE Bilirubin NEGATIVE NEGATIVE Occult Blood NEGATIVE NEGATIVE WBC NONE 0-3 HPF RBC NONE 0-3 HPF Casts NONE SEEN Hyaline 0-3 LPF Crystals NONE SEEN HPF Bacteria Epithelial Cells NONE SEEN NONE SEEN None Seen HPF HPF Fat Droplets >50 HPF RETICULOCYTE COUNT REFLEX Reticulocyte Total Abso lute Ret iculocytes 0.6 0-1 % 15000 <45,000 J?L Would you please let us know what we can do to help our cat? Thank you again, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: From Wendy at WendyFrank.Net Fri Sep 20 21:12:34 2019 From: Wendy at WendyFrank.Net (Wendy) Date: Sat, 21 Sep 2019 02:12:34 +0000 Subject: [Felvtalk] Knowledge or experience dealing with an FELV+ cat with Acute Myeloid Leukemia? Message-ID: <039023a6c8af4c74a0b0bbd6cf092875@WendyFrank.Net> Hello, Bado, our 1 and ? year old male cat is FELV+ and today was just diagnosed with acute myeloid leukemia, AML-M6, which we found because he was severely anemic, lethargic, and had decreased appetite. He is being treated with Doxy and Pred now. We see the oncologist on Tuesday. Does anyone have experience or knowledge of treatment for acute myeloid leukemia, especially in an FELV+ cat? Thank you, Wendy -------------- next part -------------- An HTML attachment was scrubbed... URL: