From cinzaeamarelo at gmail.com Sat Jun 1 11:36:05 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Sat, 1 Jun 2019 13:36:05 -0300 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: Message-ID: Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley escreveu: > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > *From:* Felvtalk * On Behalf Of *Patricia > Oliveira > *Sent:* May 30, 2019 12:56 PM > *To:* felvtalk at felineleukemia.org > *Subject:* [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > > > Patr?cia > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From aoakley at oakleylegal.com Sat Jun 1 12:43:35 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Sat, 1 Jun 2019 17:43:35 +0000 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: Message-ID: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From khrystid at yahoo.com Mon Jun 3 09:08:15 2019 From: khrystid at yahoo.com (Kristy) Date: Mon, 3 Jun 2019 09:08:15 -0500 Subject: [Felvtalk] New to Fel-V positive kitty In-Reply-To: References: Message-ID: Hi Amani! Thanks for your help! As far as I know his bloodwork came back normal other than the fever. I will talk to my vet about the meds you suggested. Unfortunately the two vets I have taken him haven?t really been forthcoming with treatment options. My husband is taking him back to the vet on Friday since we can?t seem to get the diarrhea/bloating under control. Have a great day! Kristy > On May 31, 2019, at 9:35 AM, Amani Oakley wrote: > > Hi Kristy > > The advice I repeat to everyone is that the best combination I found to treat a FeLV cat is with prednisone (prednisolone), Doxycycline and Stanozolol. I don?t know if you have run blood work to determine the haematocrit/red cell levels, but when a cat goes into crisis, it is usually because the red cells are not being replenished by the infected bone marrow (which normally produces new red cells) and the cat becomes severely anaemic. Other cell lines in the blood soon follow (white cells and platelets) because the progenitor cells which produce those blood cell lines are also found in the infected bone marrow (which is attacked by the virus). The reticulocyte count, which is a measure of new red cells being produced by the bone marrow, is very low or even zero (which it was with my cat). > > I would not wait until your cat is in crisis to start the treatment. My kitten was in severe crisis when I stumbled upon this combination therapy, and it was the only thing that worked to reverse the severe anaemia. I had tried three other treatments, while doing weekly blood testing, and none of the other treatments (Interferon, LTCI and Immunoregulin) budged his results upwards by even a single point, though I had used each treatment for weeks if not months in looking for an effective treatment. > > If I were you, I would get him on Doxycycline rather than, or at least in addition to the Clavamox. The Doxycycline has been found to interfere with cell wall production with some viruses. If this were my kitten, I would get started on the combination of prednisone/stanozolol/doxycycline right away. You might want to test the blood work to get a baseline first, but given that your kitten is not currently in crisis, that may not be entirely necessary. > > With respect to the intestinal issues, with my FeLV cat, I had identified that there was intestinal involvement and my research confirmed that the walls of the intestines can be affected by the virus. In my cat's case, the intestines were swollen and the stool seemed to sit in there for a long time. I used metoclopramide (tiny amount 1/4 to 1/5 of a tablet before each meal) to keep everything moving along, because my cat was eating and then throwing up. Metoclopramide helps with emptying of stomach contents and moving stool out of the top 1/3 of the intestines. You might consider trying the metoclopramide to see if it will help with the bloating and gas. > > Amani > > > > -----Original Message----- > From: Felvtalk On Behalf Of Kristy > Sent: May 31, 2019 9:41 AM > To: felvtalk at felineleukemia.org > Subject: [Felvtalk] New to Fel-V positive kitty > > Hi! > > My husband and I recently took in a Fel-V+ kitty that showed up outside our house a couple of months ago. We already had 7 other kitties so we had to keep Fergus (kitty?s name) isolated in the upstairs portion of our house. > > He is experiencing bloating, is very gassy, and still has diarrhea (softer stools) and I was wondering if this is a typical symptom of a positive kitty. > > He?s been to the vet and no parasites were found, but he was running a fever. He is on Clavamox to help with the fever, but other than the bloating/gas/diarrhea he is a normal kitty. We?ve tried figuring out if he had an issue or allergy to specific foods, but nothing we?ve done has changed his bloating/gas/diarrhea. He did have an ultrasound at the vet visit and there were no masses or obstructions. > > Is this possibly a symptom of the Fel-V? What sort of stuff should we be looking for? > > He?s such a sweet, loving kitty and my husband?s baby! How can we help this kitty? > > Thanks for any help you can provide! > Kristy > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org From aoakley at oakleylegal.com Mon Jun 3 11:43:47 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Mon, 3 Jun 2019 16:43:47 +0000 Subject: [Felvtalk] New to Fel-V positive kitty In-Reply-To: References: Message-ID: Hi Kristy - that's great about the blood work. However, don?t let it make you complacent. If she tested FeLV positive, and she is such a wee kitten, with all kinds of other problems, if it were me, I would want to get ahead of the problem. Also, as I've mentioned, the Stanozolol seems to be helpful for other conditions, and it also makes them feel better and improves their appetite and overall outlook on life. Please let us know how things go. We're all praying for your little kitten and thank you for having such a good heart. Amani -----Original Message----- From: Felvtalk On Behalf Of Kristy Sent: June 3, 2019 10:08 AM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] New to Fel-V positive kitty Hi Amani! Thanks for your help! As far as I know his bloodwork came back normal other than the fever. I will talk to my vet about the meds you suggested. Unfortunately the two vets I have taken him haven?t really been forthcoming with treatment options. My husband is taking him back to the vet on Friday since we can?t seem to get the diarrhea/bloating under control. Have a great day! Kristy > On May 31, 2019, at 9:35 AM, Amani Oakley wrote: > > Hi Kristy > > The advice I repeat to everyone is that the best combination I found to treat a FeLV cat is with prednisone (prednisolone), Doxycycline and Stanozolol. I don?t know if you have run blood work to determine the haematocrit/red cell levels, but when a cat goes into crisis, it is usually because the red cells are not being replenished by the infected bone marrow (which normally produces new red cells) and the cat becomes severely anaemic. Other cell lines in the blood soon follow (white cells and platelets) because the progenitor cells which produce those blood cell lines are also found in the infected bone marrow (which is attacked by the virus). The reticulocyte count, which is a measure of new red cells being produced by the bone marrow, is very low or even zero (which it was with my cat). > > I would not wait until your cat is in crisis to start the treatment. My kitten was in severe crisis when I stumbled upon this combination therapy, and it was the only thing that worked to reverse the severe anaemia. I had tried three other treatments, while doing weekly blood testing, and none of the other treatments (Interferon, LTCI and Immunoregulin) budged his results upwards by even a single point, though I had used each treatment for weeks if not months in looking for an effective treatment. > > If I were you, I would get him on Doxycycline rather than, or at least in addition to the Clavamox. The Doxycycline has been found to interfere with cell wall production with some viruses. If this were my kitten, I would get started on the combination of prednisone/stanozolol/doxycycline right away. You might want to test the blood work to get a baseline first, but given that your kitten is not currently in crisis, that may not be entirely necessary. > > With respect to the intestinal issues, with my FeLV cat, I had identified that there was intestinal involvement and my research confirmed that the walls of the intestines can be affected by the virus. In my cat's case, the intestines were swollen and the stool seemed to sit in there for a long time. I used metoclopramide (tiny amount 1/4 to 1/5 of a tablet before each meal) to keep everything moving along, because my cat was eating and then throwing up. Metoclopramide helps with emptying of stomach contents and moving stool out of the top 1/3 of the intestines. You might consider trying the metoclopramide to see if it will help with the bloating and gas. > > Amani > > > > -----Original Message----- > From: Felvtalk On Behalf Of Kristy > Sent: May 31, 2019 9:41 AM > To: felvtalk at felineleukemia.org > Subject: [Felvtalk] New to Fel-V positive kitty > > Hi! > > My husband and I recently took in a Fel-V+ kitty that showed up outside our house a couple of months ago. We already had 7 other kitties so we had to keep Fergus (kitty?s name) isolated in the upstairs portion of our house. > > He is experiencing bloating, is very gassy, and still has diarrhea (softer stools) and I was wondering if this is a typical symptom of a positive kitty. > > He?s been to the vet and no parasites were found, but he was running a fever. He is on Clavamox to help with the fever, but other than the bloating/gas/diarrhea he is a normal kitty. We?ve tried figuring out if he had an issue or allergy to specific foods, but nothing we?ve done has changed his bloating/gas/diarrhea. He did have an ultrasound at the vet visit and there were no masses or obstructions. > > Is this possibly a symptom of the Fel-V? What sort of stuff should we be looking for? > > He?s such a sweet, loving kitty and my husband?s baby! How can we help this kitty? > > Thanks for any help you can provide! > Kristy > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org From bchapel at optonline.net Mon Jun 3 12:00:11 2019 From: bchapel at optonline.net (ROBERT CHAPEL) Date: Mon, 3 Jun 2019 13:00:11 -0400 (EDT) Subject: [Felvtalk] Nori... In-Reply-To: References: Message-ID: <683737007.85391.1559581212343@mymail.optimum.net> Patricia... I don't have any better advice than is being offered by Amani... Just wanted to wish you the best with this adorable kitten and cheer you on as one of the special people with especially big hearts.... Good Luck to both of you!!! Bob from NY > On June 3, 2019 at 12:44 PM felvtalk-request at felineleukemia.org wrote: > > > Send Felvtalk mailing list submissions to > felvtalk at felineleukemia.org > > To subscribe or unsubscribe via the World Wide Web, visit > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > or, via email, send a message with subject or body 'help' to > felvtalk-request at felineleukemia.org > > You can reach the person managing the list at > felvtalk-owner at felineleukemia.org > > When replying, please edit your Subject line so it is more specific > than "Re: Contents of Felvtalk digest..." > > > Today's Topics: > > 1. Re: Rescued kitten felv + (Amani Oakley) > 2. Re: New to Fel-V positive kitty (Kristy) > 3. Re: New to Fel-V positive kitty (Amani Oakley) > > > ---------------------------------------------------------------------- > > Message: 1 > Date: Sat, 1 Jun 2019 17:43:35 +0000 > From: Amani Oakley > To: "felvtalk at felineleukemia.org" > Subject: Re: [Felvtalk] Rescued kitten felv + > Message-ID: > > Content-Type: text/plain; charset="utf-8" > > Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. > > You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. > > I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. > > Amani > > From: Felvtalk On Behalf Of Patricia Oliveira > Sent: June 1, 2019 12:36 PM > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > > Hi, Amani! > > Thanky you very much for you email! > > Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. > > Today i bought other kinds of canned, i'll try them hoping she likes some one. > > Compound pharmacy must delivery stanozolol today. > > Are there any precautions regarding medication schedules? Close or far to doxy, for example? > > This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > > > Thank you! > > Patr?cia > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: > Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. > > Amani > > From: Felvtalk > On Behalf Of Patricia Oliveira > Sent: May 30, 2019 12:56 PM > To: felvtalk at felineleukemia.org > Subject: [Felvtalk] Rescued kitten felv + > > Hi from Brazil, > > I rescued a very weak, dehydrated, extremely thin kitten. > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. > She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already receiving? > > Thank you! > > Patr?cia > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- > An HTML attachment was scrubbed... > URL: > > ------------------------------ > > Message: 2 > Date: Mon, 3 Jun 2019 09:08:15 -0500 > From: Kristy > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] New to Fel-V positive kitty > Message-ID: > Content-Type: text/plain; charset=utf-8 > > Hi Amani! > > Thanks for your help! > > As far as I know his bloodwork came back normal other than the fever. > > I will talk to my vet about the meds you suggested. Unfortunately the two vets I have taken him haven?t really been forthcoming with treatment options. > > My husband is taking him back to the vet on Friday since we can?t seem to get the diarrhea/bloating under control. > > Have a great day! > Kristy > > > On May 31, 2019, at 9:35 AM, Amani Oakley wrote: > > > > Hi Kristy > > > > The advice I repeat to everyone is that the best combination I found to treat a FeLV cat is with prednisone (prednisolone), Doxycycline and Stanozolol. I don?t know if you have run blood work to determine the haematocrit/red cell levels, but when a cat goes into crisis, it is usually because the red cells are not being replenished by the infected bone marrow (which normally produces new red cells) and the cat becomes severely anaemic. Other cell lines in the blood soon follow (white cells and platelets) because the progenitor cells which produce those blood cell lines are also found in the infected bone marrow (which is attacked by the virus). The reticulocyte count, which is a measure of new red cells being produced by the bone marrow, is very low or even zero (which it was with my cat). > > > > I would not wait until your cat is in crisis to start the treatment. My kitten was in severe crisis when I stumbled upon this combination therapy, and it was the only thing that worked to reverse the severe anaemia. I had tried three other treatments, while doing weekly blood testing, and none of the other treatments (Interferon, LTCI and Immunoregulin) budged his results upwards by even a single point, though I had used each treatment for weeks if not months in looking for an effective treatment. > > > > If I were you, I would get him on Doxycycline rather than, or at least in addition to the Clavamox. The Doxycycline has been found to interfere with cell wall production with some viruses. If this were my kitten, I would get started on the combination of prednisone/stanozolol/doxycycline right away. You might want to test the blood work to get a baseline first, but given that your kitten is not currently in crisis, that may not be entirely necessary. > > > > With respect to the intestinal issues, with my FeLV cat, I had identified that there was intestinal involvement and my research confirmed that the walls of the intestines can be affected by the virus. In my cat's case, the intestines were swollen and the stool seemed to sit in there for a long time. I used metoclopramide (tiny amount 1/4 to 1/5 of a tablet before each meal) to keep everything moving along, because my cat was eating and then throwing up. Metoclopramide helps with emptying of stomach contents and moving stool out of the top 1/3 of the intestines. You might consider trying the metoclopramide to see if it will help with the bloating and gas. > > > > Amani > > > > > > > > -----Original Message----- > > From: Felvtalk On Behalf Of Kristy > > Sent: May 31, 2019 9:41 AM > > To: felvtalk at felineleukemia.org > > Subject: [Felvtalk] New to Fel-V positive kitty > > > > Hi! > > > > My husband and I recently took in a Fel-V+ kitty that showed up outside our house a couple of months ago. We already had 7 other kitties so we had to keep Fergus (kitty?s name) isolated in the upstairs portion of our house. > > > > He is experiencing bloating, is very gassy, and still has diarrhea (softer stools) and I was wondering if this is a typical symptom of a positive kitty. > > > > He?s been to the vet and no parasites were found, but he was running a fever. He is on Clavamox to help with the fever, but other than the bloating/gas/diarrhea he is a normal kitty. We?ve tried figuring out if he had an issue or allergy to specific foods, but nothing we?ve done has changed his bloating/gas/diarrhea. He did have an ultrasound at the vet visit and there were no masses or obstructions. > > > > Is this possibly a symptom of the Fel-V? What sort of stuff should we be looking for? > > > > He?s such a sweet, loving kitty and my husband?s baby! How can we help this kitty? > > > > Thanks for any help you can provide! > > Kristy > > > > _______________________________________________ > > Felvtalk mailing list > > Felvtalk at felineleukemia.org > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > > Felvtalk mailing list > > Felvtalk at felineleukemia.org > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > ------------------------------ > > Message: 3 > Date: Mon, 3 Jun 2019 16:43:47 +0000 > From: Amani Oakley > To: "felvtalk at felineleukemia.org" > Subject: Re: [Felvtalk] New to Fel-V positive kitty > Message-ID: > > Content-Type: text/plain; charset="utf-8" > > Hi Kristy - that's great about the blood work. However, don?t let it make you complacent. If she tested FeLV positive, and she is such a wee kitten, with all kinds of other problems, if it were me, I would want to get ahead of the problem. Also, as I've mentioned, the Stanozolol seems to be helpful for other conditions, and it also makes them feel better and improves their appetite and overall outlook on life. > > Please let us know how things go. We're all praying for your little kitten and thank you for having such a good heart. > > Amani > > -----Original Message----- > From: Felvtalk On Behalf Of Kristy > Sent: June 3, 2019 10:08 AM > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] New to Fel-V positive kitty > > Hi Amani! > > Thanks for your help! > > As far as I know his bloodwork came back normal other than the fever. > > I will talk to my vet about the meds you suggested. Unfortunately the two vets I have taken him haven?t really been forthcoming with treatment options. > > My husband is taking him back to the vet on Friday since we can?t seem to get the diarrhea/bloating under control. > > Have a great day! > Kristy > > > On May 31, 2019, at 9:35 AM, Amani Oakley wrote: > > > > Hi Kristy > > > > The advice I repeat to everyone is that the best combination I found to treat a FeLV cat is with prednisone (prednisolone), Doxycycline and Stanozolol. I don?t know if you have run blood work to determine the haematocrit/red cell levels, but when a cat goes into crisis, it is usually because the red cells are not being replenished by the infected bone marrow (which normally produces new red cells) and the cat becomes severely anaemic. Other cell lines in the blood soon follow (white cells and platelets) because the progenitor cells which produce those blood cell lines are also found in the infected bone marrow (which is attacked by the virus). The reticulocyte count, which is a measure of new red cells being produced by the bone marrow, is very low or even zero (which it was with my cat). > > > > I would not wait until your cat is in crisis to start the treatment. My kitten was in severe crisis when I stumbled upon this combination therapy, and it was the only thing that worked to reverse the severe anaemia. I had tried three other treatments, while doing weekly blood testing, and none of the other treatments (Interferon, LTCI and Immunoregulin) budged his results upwards by even a single point, though I had used each treatment for weeks if not months in looking for an effective treatment. > > > > If I were you, I would get him on Doxycycline rather than, or at least in addition to the Clavamox. The Doxycycline has been found to interfere with cell wall production with some viruses. If this were my kitten, I would get started on the combination of prednisone/stanozolol/doxycycline right away. You might want to test the blood work to get a baseline first, but given that your kitten is not currently in crisis, that may not be entirely necessary. > > > > With respect to the intestinal issues, with my FeLV cat, I had identified that there was intestinal involvement and my research confirmed that the walls of the intestines can be affected by the virus. In my cat's case, the intestines were swollen and the stool seemed to sit in there for a long time. I used metoclopramide (tiny amount 1/4 to 1/5 of a tablet before each meal) to keep everything moving along, because my cat was eating and then throwing up. Metoclopramide helps with emptying of stomach contents and moving stool out of the top 1/3 of the intestines. You might consider trying the metoclopramide to see if it will help with the bloating and gas. > > > > Amani > > > > > > > > -----Original Message----- > > From: Felvtalk On Behalf Of Kristy > > Sent: May 31, 2019 9:41 AM > > To: felvtalk at felineleukemia.org > > Subject: [Felvtalk] New to Fel-V positive kitty > > > > Hi! > > > > My husband and I recently took in a Fel-V+ kitty that showed up outside our house a couple of months ago. We already had 7 other kitties so we had to keep Fergus (kitty?s name) isolated in the upstairs portion of our house. > > > > He is experiencing bloating, is very gassy, and still has diarrhea (softer stools) and I was wondering if this is a typical symptom of a positive kitty. > > > > He?s been to the vet and no parasites were found, but he was running a fever. He is on Clavamox to help with the fever, but other than the bloating/gas/diarrhea he is a normal kitty. We?ve tried figuring out if he had an issue or allergy to specific foods, but nothing we?ve done has changed his bloating/gas/diarrhea. He did have an ultrasound at the vet visit and there were no masses or obstructions. > > > > Is this possibly a symptom of the Fel-V? What sort of stuff should we be looking for? > > > > He?s such a sweet, loving kitty and my husband?s baby! How can we help this kitty? > > > > Thanks for any help you can provide! > > Kristy > > > > _______________________________________________ > > Felvtalk mailing list > > Felvtalk at felineleukemia.org > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > > Felvtalk mailing list > > Felvtalk at felineleukemia.org > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > ------------------------------ > > Subject: Digest Footer > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > ------------------------------ > > End of Felvtalk Digest, Vol 55, Issue 2 > *************************************** From drey3600 at yahoo.com Mon Jun 3 12:32:34 2019 From: drey3600 at yahoo.com (Deborah Reynolds) Date: Mon, 3 Jun 2019 17:32:34 +0000 (UTC) Subject: [Felvtalk] Please Remove Me from Email List References: <621151113.8214907.1559583154030.ref@mail.yahoo.com> Message-ID: <621151113.8214907.1559583154030@mail.yahoo.com> Thank you! -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Mon Jun 3 13:07:07 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Mon, 3 Jun 2019 15:07:07 -0300 Subject: [Felvtalk] Nori... In-Reply-To: <683737007.85391.1559581212343@mymail.optimum.net> References: <683737007.85391.1559581212343@mymail.optimum.net> Message-ID: Thank you, Robert! Till yesterday night, i was more hopeful. Nori started stanozolol on saturday and i noticed an improvement in her appetite. But last night she didn?t eat, despite looking for food. She went till plate, stir in the food, but with her mouth closed all time. She didn?t open her mouth to seize the grains of cat food. I think her neurological issues are worsening :( Today, i syringed food twice in the morning, gave her some subqs with B12 too. I am really worried because i?ll be at home only at night. Does someone have any option for neurological issues or just prednisolone ? Thank you! Patr?cia Em seg, 3 de jun de 2019 ?s 14:00, ROBERT CHAPEL escreveu: > Patricia... > I don't have any better advice than is being offered by Amani... Just > wanted to wish you the best with this adorable kitten and cheer you on as > one of the special people with especially big hearts.... Good Luck to both > of you!!! > > Bob from NY > > On June 3, 2019 at 12:44 PM felvtalk-request at felineleukemia.org wrote: > > > > > > Send Felvtalk mailing list submissions to > > felvtalk at felineleukemia.org > > > > To subscribe or unsubscribe via the World Wide Web, visit > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > or, via email, send a message with subject or body 'help' to > > felvtalk-request at felineleukemia.org > > > > You can reach the person managing the list at > > felvtalk-owner at felineleukemia.org > > > > When replying, please edit your Subject line so it is more specific > > than "Re: Contents of Felvtalk digest..." > > > > > > Today's Topics: > > > > 1. Re: Rescued kitten felv + (Amani Oakley) > > 2. Re: New to Fel-V positive kitty (Kristy) > > 3. Re: New to Fel-V positive kitty (Amani Oakley) > > > > > > ---------------------------------------------------------------------- > > > > Message: 1 > > Date: Sat, 1 Jun 2019 17:43:35 +0000 > > From: Amani Oakley > > To: "felvtalk at felineleukemia.org" > > Subject: Re: [Felvtalk] Rescued kitten felv + > > Message-ID: > > > > > Content-Type: text/plain; charset="utf-8" > > > > Hi Patricia ? I gave all the pills together, morning and evening, except > for the metoclopramide which was given ? or so before meals. The rest I > gave with the meals. I didn?t observe a problem with giving them together. > > > > You might also try baby food to get Nori to eat. Get the pureed kind > (beef or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > > > Amani > > > > From: Felvtalk On Behalf Of > Patricia Oliveira > > Sent: June 1, 2019 12:36 PM > > To: felvtalk at felineleukemia.org > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Thanky you very much for you email! > > > > Nori was discharged from the hospital yesterday night. She is eating > baby dry food. I tried canned but she didn?t accept so weel. > > > > Today i bought other kinds of canned, i'll try them hoping she likes > some one. > > > > Compound pharmacy must delivery stanozolol today. > > > > Are there any precautions regarding medication schedules? Close or far > to doxy, for example? > > > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html< > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html?fbclid=IwAR0cXMedtfi73B81pJI7QiYGwRTJf9VJp-JN7S_Tstb0ANeg0Hm4ObtFH_A > > > > > > > > Thank you! > > > > Patr?cia > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley < > aoakley at oakleylegal.com> escreveu: > > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > From: Felvtalk felvtalk-bounces at felineleukemia.org>> On Behalf Of Patricia Oliveira > > Sent: May 30, 2019 12:56 PM > > To: felvtalk at felineleukemia.org > > Subject: [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion > which raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just > weakness or neurological. Already had a seizure. > > > > She also have changes in her kidneys. It has been tested and is felv + > > > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > > > The veterinarian agreed to prescribe stanozolol. > > > > Can it be used without prednisolone, only with doxy she is already > receiving? > > > > Thank you! > > > > Patr?cia > > _______________________________________________ > > Felvtalk mailing list > > Felvtalk at felineleukemia.org > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > -------------- next part -------------- > > An HTML attachment was scrubbed... > > URL: < > http://felineleukemia.org/pipermail/felvtalk_felineleukemia.org/attachments/20190601/c3893ed4/attachment-0001.html > > > > > > ------------------------------ > > > > Message: 2 > > Date: Mon, 3 Jun 2019 09:08:15 -0500 > > From: Kristy > > To: felvtalk at felineleukemia.org > > Subject: Re: [Felvtalk] New to Fel-V positive kitty > > Message-ID: > > Content-Type: text/plain; charset=utf-8 > > > > Hi Amani! > > > > Thanks for your help! > > > > As far as I know his bloodwork came back normal other than the fever. > > > > I will talk to my vet about the meds you suggested. Unfortunately the > two vets I have taken him haven?t really been forthcoming with treatment > options. > > > > My husband is taking him back to the vet on Friday since we can?t seem > to get the diarrhea/bloating under control. > > > > Have a great day! > > Kristy > > > > > On May 31, 2019, at 9:35 AM, Amani Oakley > wrote: > > > > > > Hi Kristy > > > > > > The advice I repeat to everyone is that the best combination I found > to treat a FeLV cat is with prednisone (prednisolone), Doxycycline and > Stanozolol. I don?t know if you have run blood work to determine the > haematocrit/red cell levels, but when a cat goes into crisis, it is usually > because the red cells are not being replenished by the infected bone marrow > (which normally produces new red cells) and the cat becomes severely > anaemic. Other cell lines in the blood soon follow (white cells and > platelets) because the progenitor cells which produce those blood cell > lines are also found in the infected bone marrow (which is attacked by the > virus). The reticulocyte count, which is a measure of new red cells being > produced by the bone marrow, is very low or even zero (which it was with my > cat). > > > > > > I would not wait until your cat is in crisis to start the treatment. > My kitten was in severe crisis when I stumbled upon this combination > therapy, and it was the only thing that worked to reverse the severe > anaemia. I had tried three other treatments, while doing weekly blood > testing, and none of the other treatments (Interferon, LTCI and > Immunoregulin) budged his results upwards by even a single point, though I > had used each treatment for weeks if not months in looking for an effective > treatment. > > > > > > If I were you, I would get him on Doxycycline rather than, or at least > in addition to the Clavamox. The Doxycycline has been found to interfere > with cell wall production with some viruses. If this were my kitten, I > would get started on the combination of prednisone/stanozolol/doxycycline > right away. You might want to test the blood work to get a baseline first, > but given that your kitten is not currently in crisis, that may not be > entirely necessary. > > > > > > With respect to the intestinal issues, with my FeLV cat, I had > identified that there was intestinal involvement and my research confirmed > that the walls of the intestines can be affected by the virus. In my cat's > case, the intestines were swollen and the stool seemed to sit in there for > a long time. I used metoclopramide (tiny amount 1/4 to 1/5 of a tablet > before each meal) to keep everything moving along, because my cat was > eating and then throwing up. Metoclopramide helps with emptying of stomach > contents and moving stool out of the top 1/3 of the intestines. You might > consider trying the metoclopramide to see if it will help with the bloating > and gas. > > > > > > Amani > > > > > > > > > > > > -----Original Message----- > > > From: Felvtalk On Behalf Of > Kristy > > > Sent: May 31, 2019 9:41 AM > > > To: felvtalk at felineleukemia.org > > > Subject: [Felvtalk] New to Fel-V positive kitty > > > > > > Hi! > > > > > > My husband and I recently took in a Fel-V+ kitty that showed up > outside our house a couple of months ago. We already had 7 other kitties so > we had to keep Fergus (kitty?s name) isolated in the upstairs portion of > our house. > > > > > > He is experiencing bloating, is very gassy, and still has diarrhea > (softer stools) and I was wondering if this is a typical symptom of a > positive kitty. > > > > > > He?s been to the vet and no parasites were found, but he was running a > fever. He is on Clavamox to help with the fever, but other than the > bloating/gas/diarrhea he is a normal kitty. We?ve tried figuring out if he > had an issue or allergy to specific foods, but nothing we?ve done has > changed his bloating/gas/diarrhea. He did have an ultrasound at the vet > visit and there were no masses or obstructions. > > > > > > Is this possibly a symptom of the Fel-V? What sort of stuff should we > be looking for? > > > > > > He?s such a sweet, loving kitty and my husband?s baby! How can we > help this kitty? > > > > > > Thanks for any help you can provide! > > > Kristy > > > > > > _______________________________________________ > > > Felvtalk mailing list > > > Felvtalk at felineleukemia.org > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > _______________________________________________ > > > Felvtalk mailing list > > > Felvtalk at felineleukemia.org > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > > > > > > ------------------------------ > > > > Message: 3 > > Date: Mon, 3 Jun 2019 16:43:47 +0000 > > From: Amani Oakley > > To: "felvtalk at felineleukemia.org" > > Subject: Re: [Felvtalk] New to Fel-V positive kitty > > Message-ID: > > > > > Content-Type: text/plain; charset="utf-8" > > > > Hi Kristy - that's great about the blood work. However, don?t let it > make you complacent. If she tested FeLV positive, and she is such a wee > kitten, with all kinds of other problems, if it were me, I would want to > get ahead of the problem. Also, as I've mentioned, the Stanozolol seems to > be helpful for other conditions, and it also makes them feel better and > improves their appetite and overall outlook on life. > > > > Please let us know how things go. We're all praying for your little > kitten and thank you for having such a good heart. > > > > Amani > > > > -----Original Message----- > > From: Felvtalk On Behalf Of Kristy > > Sent: June 3, 2019 10:08 AM > > To: felvtalk at felineleukemia.org > > Subject: Re: [Felvtalk] New to Fel-V positive kitty > > > > Hi Amani! > > > > Thanks for your help! > > > > As far as I know his bloodwork came back normal other than the fever. > > > > I will talk to my vet about the meds you suggested. Unfortunately the > two vets I have taken him haven?t really been forthcoming with treatment > options. > > > > My husband is taking him back to the vet on Friday since we can?t seem > to get the diarrhea/bloating under control. > > > > Have a great day! > > Kristy > > > > > On May 31, 2019, at 9:35 AM, Amani Oakley > wrote: > > > > > > Hi Kristy > > > > > > The advice I repeat to everyone is that the best combination I found > to treat a FeLV cat is with prednisone (prednisolone), Doxycycline and > Stanozolol. I don?t know if you have run blood work to determine the > haematocrit/red cell levels, but when a cat goes into crisis, it is usually > because the red cells are not being replenished by the infected bone marrow > (which normally produces new red cells) and the cat becomes severely > anaemic. Other cell lines in the blood soon follow (white cells and > platelets) because the progenitor cells which produce those blood cell > lines are also found in the infected bone marrow (which is attacked by the > virus). The reticulocyte count, which is a measure of new red cells being > produced by the bone marrow, is very low or even zero (which it was with my > cat). > > > > > > I would not wait until your cat is in crisis to start the treatment. > My kitten was in severe crisis when I stumbled upon this combination > therapy, and it was the only thing that worked to reverse the severe > anaemia. I had tried three other treatments, while doing weekly blood > testing, and none of the other treatments (Interferon, LTCI and > Immunoregulin) budged his results upwards by even a single point, though I > had used each treatment for weeks if not months in looking for an effective > treatment. > > > > > > If I were you, I would get him on Doxycycline rather than, or at least > in addition to the Clavamox. The Doxycycline has been found to interfere > with cell wall production with some viruses. If this were my kitten, I > would get started on the combination of prednisone/stanozolol/doxycycline > right away. You might want to test the blood work to get a baseline first, > but given that your kitten is not currently in crisis, that may not be > entirely necessary. > > > > > > With respect to the intestinal issues, with my FeLV cat, I had > identified that there was intestinal involvement and my research confirmed > that the walls of the intestines can be affected by the virus. In my cat's > case, the intestines were swollen and the stool seemed to sit in there for > a long time. I used metoclopramide (tiny amount 1/4 to 1/5 of a tablet > before each meal) to keep everything moving along, because my cat was > eating and then throwing up. Metoclopramide helps with emptying of stomach > contents and moving stool out of the top 1/3 of the intestines. You might > consider trying the metoclopramide to see if it will help with the bloating > and gas. > > > > > > Amani > > > > > > > > > > > > -----Original Message----- > > > From: Felvtalk On Behalf Of > Kristy > > > Sent: May 31, 2019 9:41 AM > > > To: felvtalk at felineleukemia.org > > > Subject: [Felvtalk] New to Fel-V positive kitty > > > > > > Hi! > > > > > > My husband and I recently took in a Fel-V+ kitty that showed up > outside our house a couple of months ago. We already had 7 other kitties so > we had to keep Fergus (kitty?s name) isolated in the upstairs portion of > our house. > > > > > > He is experiencing bloating, is very gassy, and still has diarrhea > (softer stools) and I was wondering if this is a typical symptom of a > positive kitty. > > > > > > He?s been to the vet and no parasites were found, but he was running a > fever. He is on Clavamox to help with the fever, but other than the > bloating/gas/diarrhea he is a normal kitty. We?ve tried figuring out if he > had an issue or allergy to specific foods, but nothing we?ve done has > changed his bloating/gas/diarrhea. He did have an ultrasound at the vet > visit and there were no masses or obstructions. > > > > > > Is this possibly a symptom of the Fel-V? What sort of stuff should we > be looking for? > > > > > > He?s such a sweet, loving kitty and my husband?s baby! How can we > help this kitty? > > > > > > Thanks for any help you can provide! > > > Kristy > > > > > > _______________________________________________ > > > Felvtalk mailing list > > > Felvtalk at felineleukemia.org > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > _______________________________________________ > > > Felvtalk mailing list > > > Felvtalk at felineleukemia.org > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > > _______________________________________________ > > Felvtalk mailing list > > Felvtalk at felineleukemia.org > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > ------------------------------ > > > > Subject: Digest Footer > > > > _______________________________________________ > > Felvtalk mailing list > > Felvtalk at felineleukemia.org > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > > ------------------------------ > > > > End of Felvtalk Digest, Vol 55, Issue 2 > > *************************************** > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Tue Jun 4 17:34:22 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Tue, 4 Jun 2019 19:34:22 -0300 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: Message-ID: Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley escreveu: > Hi Patricia ? I gave all the pills together, morning and evening, except > for the metoclopramide which was given ? or so before meals. The rest I > gave with the meals. I didn?t observe a problem with giving them together. > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef > or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > > > Amani > > > > *From:* Felvtalk * On Behalf Of *Patricia > Oliveira > *Sent:* June 1, 2019 12:36 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Thanky you very much for you email! > > > > Nori was discharged from the hospital yesterday night. She is eating baby > dry food. I tried canned but she didn?t accept so weel. > > > > Today i bought other kinds of canned, i'll try them hoping she likes some > one. > > > > Compound pharmacy must delivery stanozolol today. > > > > Are there any precautions regarding medication schedules? Close or far to > doxy, for example? > > > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > > > > > > > Thank you! > > > > Patr?cia > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: > > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* May 30, 2019 12:56 PM > *To:* felvtalk at felineleukemia.org > *Subject:* [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > > > Patr?cia > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Tue Jun 4 18:50:30 2019 From: johnston1110 at comcast.net (Lorraine Johnston) Date: Tue, 4 Jun 2019 19:50:30 -0400 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: Message-ID: <002201d51b30$4ff19430$efd4bc90$@net> Patricia, I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] On Behalf Of Patricia Oliveira Sent: Tuesday, June 4, 2019 6:34 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley escreveu: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Tue Jun 4 19:53:14 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Tue, 4 Jun 2019 21:53:14 -0300 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: <002201d51b30$4ff19430$efd4bc90$@net> References: <002201d51b30$4ff19430$efd4bc90$@net> Message-ID: Hi, Lorraine Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). :( Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < johnston1110 at comcast.net> escreveu: > Patricia, > > > > I would go with the transfusion and also start erythropoietin. Stanozolol > is supposed to stimulate erythropoietin production, but she might need a > boost of the ready-made drug just to keep her alive until then. > > > > - Lorraine > > > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > > > *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On Behalf > Of *Patricia Oliveira > *Sent:* Tuesday, June 4, 2019 6:34 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, > > > > We did another blood work today, her hematocrit is 13% now :( > > > > She is very sleepy but responsive when i talk to her. > > > > I don?t know if i can wait some more days to see if stanozolol is working. > Or maybe it would be better get another transfusion right now. > > > > Today, vet talk about erythropoietin. Do you know if it can be used with > stanozolol? > > > > Thank you, > > > > Patr?cia > > > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: > > Hi Patricia ? I gave all the pills together, morning and evening, except > for the metoclopramide which was given ? or so before meals. The rest I > gave with the meals. I didn?t observe a problem with giving them together. > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef > or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 1, 2019 12:36 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Thanky you very much for you email! > > > > Nori was discharged from the hospital yesterday night. She is eating baby > dry food. I tried canned but she didn?t accept so weel. > > > > Today i bought other kinds of canned, i'll try them hoping she likes some > one. > > > > Compound pharmacy must delivery stanozolol today. > > > > Are there any precautions regarding medication schedules? Close or far to > doxy, for example? > > > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > > > > > > > Thank you! > > > > Patr?cia > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: > > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* May 30, 2019 12:56 PM > *To:* felvtalk at felineleukemia.org > *Subject:* [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > > > Patr?cia > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From aoakley at oakleylegal.com Tue Jun 4 21:11:32 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Wed, 5 Jun 2019 02:11:32 +0000 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: Message-ID: I don?t know if erythropoietin can be used with Stanozolol, but I don?t see why not. However, I am not sure that erythropoetin will help. Not to bore everyone silly again with this explanation, but erythropoietin stimulates the bone marrow to make more red cells. However, the bone marrow which is damaged by the FeLV virus, cannot respond to the signals being sent by the erythropoietin and is unable to make more red cells. The Stanozolol works on the bone marrow itself to produce new bone marrow cells, and thus, enable the new cells to produce red cells again. So no, the Stanozolol doesn?t increase erythropoietin. If it is going to work, it seems to work directly on the bone marrow, and especially on the progenitor cells in the bone marrow which produce the red cells. Are you giving the stanozolol with the Doxycycline and prednisone? If it were me, I would proceed with the blood transfusion, and double up the Stanozolol. I don?t know what level you?re giving. 1 mg twice daily or 2 mg twice daily. Try increasing the strength. Athletes take stanozolol at 1000X recommended dosing and rarely suffer any side effects. The other thing to be aware of in interpreting your blood results is this. The life span of red cells is about 45 days if I remember correctly, so you will have a falling off of the haematocrit as the red cells from the last transfusion die off. Look to see what the reticulocyte count is, and what it is now compared to a previous blood result. However, even that result may also be affected by the transfusion, so I am not sure if you would see the true numbers or see the transfused cells instead. In other words, the dropping of the haematocrit may be more about the natural dying off of the last batch of red cells, rather than whether there is any effect yet of the meds. Nonetheless, to be on the safe side, if you are worried, go ahead with the transfusion. Amani From: Felvtalk On Behalf Of Patricia Oliveira Sent: June 4, 2019 6:34 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From aoakley at oakleylegal.com Tue Jun 4 21:45:43 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Wed, 5 Jun 2019 02:45:43 +0000 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> Message-ID: I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. Amani From: Felvtalk On Behalf Of Patricia Oliveira Sent: June 4, 2019 8:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Lorraine Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). :( Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston > escreveu: Patricia, I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] On Behalf Of Patricia Oliveira Sent: Tuesday, June 4, 2019 6:34 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Fri Jun 7 11:52:37 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Fri, 7 Jun 2019 13:52:37 -0300 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> Message-ID: Hi, Amani! Nori got another transfusion last night, hematocrit was 11.9 before it. Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. i am worried again. Thank you, Patr?cia Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley escreveu: > I would be leery of the going the route suggested by the vet at this > juncture. I seriously seriously doubt if the erythropoietin will help. See > my earlier where I explain why. > > > > Amani > > > > *From:* Felvtalk * On Behalf Of *Patricia > Oliveira > *Sent:* June 4, 2019 8:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Lorraine > > > > Veterinary wants to increase prednisolone to immunosuppressive dose and > add erythropoietin. She thinks it is immune-mediated anemia and > not mycoplasma. > > > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > > > We did x-ray today too. No visible tumor but we found a > possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > :( > > > > > > > > Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < > johnston1110 at comcast.net> escreveu: > > Patricia, > > > > I would go with the transfusion and also start erythropoietin. Stanozolol > is supposed to stimulate erythropoietin production, but she might need a > boost of the ready-made drug just to keep her alive until then. > > > > - Lorraine > > > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > > > *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On Behalf > Of *Patricia Oliveira > *Sent:* Tuesday, June 4, 2019 6:34 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, > > > > We did another blood work today, her hematocrit is 13% now :( > > > > She is very sleepy but responsive when i talk to her. > > > > I don?t know if i can wait some more days to see if stanozolol is working. > Or maybe it would be better get another transfusion right now. > > > > Today, vet talk about erythropoietin. Do you know if it can be used with > stanozolol? > > > > Thank you, > > > > Patr?cia > > > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: > > Hi Patricia ? I gave all the pills together, morning and evening, except > for the metoclopramide which was given ? or so before meals. The rest I > gave with the meals. I didn?t observe a problem with giving them together. > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef > or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 1, 2019 12:36 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Thanky you very much for you email! > > > > Nori was discharged from the hospital yesterday night. She is eating baby > dry food. I tried canned but she didn?t accept so weel. > > > > Today i bought other kinds of canned, i'll try them hoping she likes some > one. > > > > Compound pharmacy must delivery stanozolol today. > > > > Are there any precautions regarding medication schedules? Close or far to > doxy, for example? > > > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > > > > > > > Thank you! > > > > Patr?cia > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: > > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* May 30, 2019 12:56 PM > *To:* felvtalk at felineleukemia.org > *Subject:* [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > > > Patr?cia > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From aoakley at oakleylegal.com Fri Jun 7 12:12:20 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Fri, 7 Jun 2019 17:12:20 +0000 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> Message-ID: Hi Patricia The Stanozolol often has a side-effect of elevating liver enzymes, though I cannot remember if it also increased bilirubin (which would be what would cause the icteric observation of the plasma). However, hang in there. If it is the Stanozolol, my experience is that the liver enzymes drop right back to normal, shortly after it is discontinued, and there is no lasting damage to the liver. For now, what you have described (low temp and slightly lower heart rate) seems more likely to be related to the transfusion itself, rather than anything else going on. It is also possible that with the additional transfusion, there is a higher than normal red cell destruction going on, which would be another explanation for the increased icterus in the blood (which will also show as an increase in bilirubin). Elevated bilirubin can often be caused by a reaction to a blood transfusion. If the high bilirubin is the indirect or the unconjugated portion, it is related to red cell break down. The direct bilirubin (conjugated portion) is related to liver function. The lab results are usually broken down to Total bilirubin and Direct bilirubin. The indirect portion is obtained by subtracting the direct amount from the total amount. I myself went through the pressure of the vets wanting me to discontinue the Stanozolol because of abnormal liver enzymes. My logic was that there was nothing else. If I discontinued the Stanozolol, my cat would die, period. I continued and found that in the end, the liver enzymes normalized on their own, even though I had Zander on almost continuous Stanozolol for close to two years. I know that you know that you are only temporarily helping Nori with blood transfusions, and the virus is still attacking cells, etc. In my opinion ? and mine alone ? my experience and research leads me to the conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell production, but I believe that the Doxycyline assisted in keeping the viruses from properly reproducing. However, anticipate that when the vet gets back the second set of blood work, she may well try to tell you to discontinue the Stanozolol. Amani From: Felvtalk On Behalf Of Patricia Oliveira Sent: June 7, 2019 12:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Nori got another transfusion last night, hematocrit was 11.9 before it. Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. i am worried again. Thank you, Patr?cia Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 4, 2019 8:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Lorraine Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). :( Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston > escreveu: Patricia, I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] On Behalf Of Patricia Oliveira Sent: Tuesday, June 4, 2019 6:34 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Fri Jun 7 12:28:10 2019 From: johnston1110 at comcast.net (Lorraine Johnston) Date: Fri, 7 Jun 2019 13:28:10 -0400 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> Message-ID: <006801d51d56$614eba00$23ec2e00$@net> Patricia, Has Nori been tested for mycoplasma? That can cause a sometimes fatal anemia and is treated (usually) with doxycycline. http://veterinarymedicine.dvm360.com/help-clients-stay-optimistic-when-felv-results-are-positive Also, some members of the FIV-Healthscience discussion group are having very good luck with the broad antiviral RetroMad1 (RM1), from Malaysia, for their FeLV cats. If you want a few contacts to discuss this drug with, let me know and I?ll pass them along. Best regards, - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing . . . . . . . . . . . . . . . . . Hi, Amani! Nori got another transfusion last night, hematocrit was 11.9 before it. Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. i am worried again. Thank you, Patr?cia -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Fri Jun 7 12:43:47 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Fri, 7 Jun 2019 14:43:47 -0300 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> Message-ID: Hi, Amani Nori is receiving doxy+prenisolone+stanazolol even in the hospital. I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don?t remember if it was icteric plasma on last one. I was hopefull she would come back home tomorrow, now i don?t know if it will be possible. Today she must have am echocardiogram too because x-ray showed an enlarged heart. Thank you! Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley escreveu: > Hi Patricia > > > > The Stanozolol often has a side-effect of elevating liver enzymes, though > I cannot remember if it also increased bilirubin (which would be what would > cause the icteric observation of the plasma). However, hang in there. If it > is the Stanozolol, my experience is that the liver enzymes drop right back > to normal, shortly after it is discontinued, and there is no lasting damage > to the liver. For now, what you have described (low temp and slightly lower > heart rate) seems more likely to be related to the transfusion itself, > rather than anything else going on. > > > > It is also possible that with the additional transfusion, there is a > higher than normal red cell destruction going on, which would be another > explanation for the increased icterus in the blood (which will also show as > an increase in bilirubin). Elevated bilirubin can often be caused by a > reaction to a blood transfusion. If the high bilirubin is the indirect or > the unconjugated portion, it is related to red cell break down. The direct > bilirubin (conjugated portion) is related to liver function. The lab > results are usually broken down to Total bilirubin and Direct bilirubin. > The indirect portion is obtained by subtracting the direct amount from the > total amount. > > > > I myself went through the pressure of the vets wanting me to discontinue > the Stanozolol because of abnormal liver enzymes. My logic was that there > was nothing else. If I discontinued the Stanozolol, my cat would die, > period. I continued and found that in the end, the liver enzymes normalized > on their own, even though I had Zander on almost continuous Stanozolol for > close to two years. > > > > I know that you know that you are only temporarily helping Nori with blood > transfusions, and the virus is still attacking cells, etc. In my opinion ? > and mine alone ? my experience and research leads me to the conclusion that > the combination of Doxycycline/Prednisone/Stanozolol worked to not only > boost the red cell production, but I believe that the Doxycyline assisted > in keeping the viruses from properly reproducing. > > > > However, anticipate that when the vet gets back the second set of blood > work, she may well try to tell you to discontinue the Stanozolol. > > > > Amani > > > > > > > > *From:* Felvtalk * On Behalf Of *Patricia > Oliveira > *Sent:* June 7, 2019 12:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > > > Today morning, i talk to the hospital's veterinarian, she said hematocrit > went to 29 and Nori was fine, all normal parameters and eating by herself > again. > > > > But plasma was intensely icteric. I think this means red cells being > destroyed, isn't it? > > > > About one hour ago, veterinarian said Nori was with low temperature and > heart rate slightly lower than normal. She was waiting the new blood work. > In the morning, it was done only hematocrit, not complete blood work. > > > > i am worried again. > > > > Thank you, > > > > Patr?cia > > > > Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: > > I would be leery of the going the route suggested by the vet at this > juncture. I seriously seriously doubt if the erythropoietin will help. See > my earlier where I explain why. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 4, 2019 8:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Lorraine > > > > Veterinary wants to increase prednisolone to immunosuppressive dose and > add erythropoietin. She thinks it is immune-mediated anemia and > not mycoplasma. > > > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > > > We did x-ray today too. No visible tumor but we found a > possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > :( > > > > > > > > Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < > johnston1110 at comcast.net> escreveu: > > Patricia, > > > > I would go with the transfusion and also start erythropoietin. Stanozolol > is supposed to stimulate erythropoietin production, but she might need a > boost of the ready-made drug just to keep her alive until then. > > > > - Lorraine > > > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > > > *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On Behalf > Of *Patricia Oliveira > *Sent:* Tuesday, June 4, 2019 6:34 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, > > > > We did another blood work today, her hematocrit is 13% now :( > > > > She is very sleepy but responsive when i talk to her. > > > > I don?t know if i can wait some more days to see if stanozolol is working. > Or maybe it would be better get another transfusion right now. > > > > Today, vet talk about erythropoietin. Do you know if it can be used with > stanozolol? > > > > Thank you, > > > > Patr?cia > > > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: > > Hi Patricia ? I gave all the pills together, morning and evening, except > for the metoclopramide which was given ? or so before meals. The rest I > gave with the meals. I didn?t observe a problem with giving them together. > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef > or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 1, 2019 12:36 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Thanky you very much for you email! > > > > Nori was discharged from the hospital yesterday night. She is eating baby > dry food. I tried canned but she didn?t accept so weel. > > > > Today i bought other kinds of canned, i'll try them hoping she likes some > one. > > > > Compound pharmacy must delivery stanozolol today. > > > > Are there any precautions regarding medication schedules? Close or far to > doxy, for example? > > > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > > > > > > > Thank you! > > > > Patr?cia > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: > > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* May 30, 2019 12:56 PM > *To:* felvtalk at felineleukemia.org > *Subject:* [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > > > Patr?cia > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Fri Jun 7 13:31:32 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Fri, 7 Jun 2019 15:31:32 -0300 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: <006801d51d56$614eba00$23ec2e00$@net> References: <002201d51b30$4ff19430$efd4bc90$@net> <006801d51d56$614eba00$23ec2e00$@net> Message-ID: Hi, Lorraine Yes, she was and test was negative. But she is receiving doxy for it, anyway. I?d like the contacts about RetroMad, please! Thank you! Patr?cia Em sex, 7 de jun de 2019 ?s 14:28, Lorraine Johnston < johnston1110 at comcast.net> escreveu: > Patricia, > > > > Has Nori been tested for mycoplasma? That can cause a sometimes fatal > anemia and is treated (usually) with doxycycline. > > > > > http://veterinarymedicine.dvm360.com/help-clients-stay-optimistic-when-felv-results-are-positive > > > > Also, some members of the FIV-Healthscience discussion group are having > very good luck with the broad antiviral RetroMad1 (RM1), from Malaysia, for > their FeLV cats. If you want a few contacts to discuss this drug with, let > me know and I?ll pass them along. > > > > > > Best regards, > > > > - Lorraine > > > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > > > . . . . . . . . . . . . . . . . . > > > > Hi, Amani! > > > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > > > Today morning, i talk to the hospital's veterinarian, she said hematocrit > went to 29 and Nori was fine, all normal parameters and eating by herself > again. > > > > But plasma was intensely icteric. I think this means red cells being > destroyed, isn't it? > > > > About one hour ago, veterinarian said Nori was with low temperature and > heart rate slightly lower than normal. She was waiting the new blood work. > In the morning, it was done only hematocrit, not complete blood work. > > > > i am worried again. > > > > Thank you, > > > > Patr?cia > > > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From aoakley at oakleylegal.com Fri Jun 7 14:11:23 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Fri, 7 Jun 2019 19:11:23 +0000 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> Message-ID: Still sounds more like a transfusion reaction than anything with the meds. Hang in there. See what the afternoon labs show. Amani From: Felvtalk On Behalf Of Patricia Oliveira Sent: June 7, 2019 1:44 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani Nori is receiving doxy+prenisolone+stanazolol even in the hospital. I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don?t remember if it was icteric plasma on last one. I was hopefull she would come back home tomorrow, now i don?t know if it will be possible. Today she must have am echocardiogram too because x-ray showed an enlarged heart. Thank you! Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: Hi Patricia The Stanozolol often has a side-effect of elevating liver enzymes, though I cannot remember if it also increased bilirubin (which would be what would cause the icteric observation of the plasma). However, hang in there. If it is the Stanozolol, my experience is that the liver enzymes drop right back to normal, shortly after it is discontinued, and there is no lasting damage to the liver. For now, what you have described (low temp and slightly lower heart rate) seems more likely to be related to the transfusion itself, rather than anything else going on. It is also possible that with the additional transfusion, there is a higher than normal red cell destruction going on, which would be another explanation for the increased icterus in the blood (which will also show as an increase in bilirubin). Elevated bilirubin can often be caused by a reaction to a blood transfusion. If the high bilirubin is the indirect or the unconjugated portion, it is related to red cell break down. The direct bilirubin (conjugated portion) is related to liver function. The lab results are usually broken down to Total bilirubin and Direct bilirubin. The indirect portion is obtained by subtracting the direct amount from the total amount. I myself went through the pressure of the vets wanting me to discontinue the Stanozolol because of abnormal liver enzymes. My logic was that there was nothing else. If I discontinued the Stanozolol, my cat would die, period. I continued and found that in the end, the liver enzymes normalized on their own, even though I had Zander on almost continuous Stanozolol for close to two years. I know that you know that you are only temporarily helping Nori with blood transfusions, and the virus is still attacking cells, etc. In my opinion ? and mine alone ? my experience and research leads me to the conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell production, but I believe that the Doxycyline assisted in keeping the viruses from properly reproducing. However, anticipate that when the vet gets back the second set of blood work, she may well try to tell you to discontinue the Stanozolol. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 12:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Nori got another transfusion last night, hematocrit was 11.9 before it. Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. i am worried again. Thank you, Patr?cia Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 4, 2019 8:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Lorraine Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). :( Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston > escreveu: Patricia, I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] On Behalf Of Patricia Oliveira Sent: Tuesday, June 4, 2019 6:34 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Fri Jun 7 14:28:02 2019 From: johnston1110 at comcast.net (Lorraine Johnston) Date: Fri, 7 Jun 2019 15:28:02 -0400 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <006801d51d56$614eba00$23ec2e00$@net> Message-ID: <009e01d51d67$200f2c80$602d8580$@net> Hi, Patricia, I?ve asked fiv-healthscience members using RetroMad1 for FeLV cats to contact me if it?s okay to pass their email addresses along to you. In the meantime, this is what fiv-healthscience website manager Joel Kehler has written about RetroMad1: http://www.fivtherapy.com/fiv_news.htm#RetroMAD1%20(IV) Best regards, - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing . . . . . . . . . . . . . . . . . . Hi, Lorraine Yes, she was and test was negative. But she is receiving doxy for it, anyway. I?d like the contacts about RetroMad, please! Thank you! Patr?cia -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Fri Jun 7 20:55:40 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Fri, 7 Jun 2019 22:55:40 -0300 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> Message-ID: Nori did not want to eat by herself so they are syringing food. They started another medication for nausea, although she does not vomit, they think that may be why she does not eat. Blood work showed changes in neutrophils (bizarre core?), veternary says it can be from leukemia. The result of this transfusion was not as good as the other time :( i?ll talk to veterinary tomorrow morning again. thank you! Patr?cia Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley escreveu: > Still sounds more like a transfusion reaction than anything with the meds. > > > > Hang in there. See what the afternoon labs show. > > > > Amani > > > > *From:* Felvtalk * On Behalf Of *Patricia > Oliveira > *Sent:* June 7, 2019 1:44 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani > > > > Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > > > > I know it can be a reaction but i thought higher dose of prednisolone > would prevent hemolysis. > > > > I also know it's normal for part of the red blood cells to be cleared > right after the transfusion, but i don?t remember if it was icteric plasma > on last one. > > > > I was hopefull she would come back home tomorrow, now i don?t know if it > will be possible. > > > > Today she must have am echocardiogram too because x-ray showed an enlarged > heart. > > > > Thank you! > > > > > > > > Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: > > Hi Patricia > > > > The Stanozolol often has a side-effect of elevating liver enzymes, though > I cannot remember if it also increased bilirubin (which would be what would > cause the icteric observation of the plasma). However, hang in there. If it > is the Stanozolol, my experience is that the liver enzymes drop right back > to normal, shortly after it is discontinued, and there is no lasting damage > to the liver. For now, what you have described (low temp and slightly lower > heart rate) seems more likely to be related to the transfusion itself, > rather than anything else going on. > > > > It is also possible that with the additional transfusion, there is a > higher than normal red cell destruction going on, which would be another > explanation for the increased icterus in the blood (which will also show as > an increase in bilirubin). Elevated bilirubin can often be caused by a > reaction to a blood transfusion. If the high bilirubin is the indirect or > the unconjugated portion, it is related to red cell break down. The direct > bilirubin (conjugated portion) is related to liver function. The lab > results are usually broken down to Total bilirubin and Direct bilirubin. > The indirect portion is obtained by subtracting the direct amount from the > total amount. > > > > I myself went through the pressure of the vets wanting me to discontinue > the Stanozolol because of abnormal liver enzymes. My logic was that there > was nothing else. If I discontinued the Stanozolol, my cat would die, > period. I continued and found that in the end, the liver enzymes normalized > on their own, even though I had Zander on almost continuous Stanozolol for > close to two years. > > > > I know that you know that you are only temporarily helping Nori with blood > transfusions, and the virus is still attacking cells, etc. In my opinion ? > and mine alone ? my experience and research leads me to the conclusion that > the combination of Doxycycline/Prednisone/Stanozolol worked to not only > boost the red cell production, but I believe that the Doxycyline assisted > in keeping the viruses from properly reproducing. > > > > However, anticipate that when the vet gets back the second set of blood > work, she may well try to tell you to discontinue the Stanozolol. > > > > Amani > > > > > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 7, 2019 12:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > > > Today morning, i talk to the hospital's veterinarian, she said hematocrit > went to 29 and Nori was fine, all normal parameters and eating by herself > again. > > > > But plasma was intensely icteric. I think this means red cells being > destroyed, isn't it? > > > > About one hour ago, veterinarian said Nori was with low temperature and > heart rate slightly lower than normal. She was waiting the new blood work. > In the morning, it was done only hematocrit, not complete blood work. > > > > i am worried again. > > > > Thank you, > > > > Patr?cia > > > > Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: > > I would be leery of the going the route suggested by the vet at this > juncture. I seriously seriously doubt if the erythropoietin will help. See > my earlier where I explain why. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 4, 2019 8:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Lorraine > > > > Veterinary wants to increase prednisolone to immunosuppressive dose and > add erythropoietin. She thinks it is immune-mediated anemia and > not mycoplasma. > > > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > > > We did x-ray today too. No visible tumor but we found a > possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > :( > > > > > > > > Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < > johnston1110 at comcast.net> escreveu: > > Patricia, > > > > I would go with the transfusion and also start erythropoietin. Stanozolol > is supposed to stimulate erythropoietin production, but she might need a > boost of the ready-made drug just to keep her alive until then. > > > > - Lorraine > > > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > > > *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On Behalf > Of *Patricia Oliveira > *Sent:* Tuesday, June 4, 2019 6:34 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, > > > > We did another blood work today, her hematocrit is 13% now :( > > > > She is very sleepy but responsive when i talk to her. > > > > I don?t know if i can wait some more days to see if stanozolol is working. > Or maybe it would be better get another transfusion right now. > > > > Today, vet talk about erythropoietin. Do you know if it can be used with > stanozolol? > > > > Thank you, > > > > Patr?cia > > > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: > > Hi Patricia ? I gave all the pills together, morning and evening, except > for the metoclopramide which was given ? or so before meals. The rest I > gave with the meals. I didn?t observe a problem with giving them together. > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef > or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 1, 2019 12:36 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Thanky you very much for you email! > > > > Nori was discharged from the hospital yesterday night. She is eating baby > dry food. I tried canned but she didn?t accept so weel. > > > > Today i bought other kinds of canned, i'll try them hoping she likes some > one. > > > > Compound pharmacy must delivery stanozolol today. > > > > Are there any precautions regarding medication schedules? Close or far to > doxy, for example? > > > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > > > > > > > Thank you! > > > > Patr?cia > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: > > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* May 30, 2019 12:56 PM > *To:* felvtalk at felineleukemia.org > *Subject:* [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > > > Patr?cia > > -------------- next part -------------- An HTML attachment was scrubbed... URL: From swacht1946 at comcast.net Sat Jun 8 09:40:25 2019 From: swacht1946 at comcast.net (Sandra Wachtstetter) Date: Sat, 8 Jun 2019 10:40:25 -0400 (EDT) Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> Message-ID: <1605332536.612607.1560004826102@connect.xfinity.com> Hello Patricia, you may already be doing this - but if not, please take a copy of Amani's conversations for the vet to read - may help. Good luck - don't give up!! Sandt W > On June 7, 2019 at 9:55 PM Patricia Oliveira wrote: > > Nori did not want to eat by herself so they are syringing food. They started another medication for nausea, although she does not vomit, they think that may be why she does not eat. > > Blood work showed changes in neutrophils (bizarre core?), veternary says it can be from leukemia. > > The result of this transfusion was not as good as the other time :( > > i?ll talk to veterinary tomorrow morning again. > > thank you! > > Patr?cia > > > > Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com mailto:aoakley at oakleylegal.com > escreveu: > > > > > > Still sounds more like a transfusion reaction than anything with the meds. > > > > > > > > Hang in there. See what the afternoon labs show. > > > > > > > > Amani > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > Sent: June 7, 2019 1:44 PM > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > Hi, Amani > > > > > > > > Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > > > > > > > > I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. > > > > > > > > I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don?t remember if it was icteric plasma on last one. > > > > > > > > I was hopefull she would come back home tomorrow, now i don?t know if it will be possible. > > > > > > > > Today she must have am echocardiogram too because x-ray showed an enlarged heart. > > > > > > > > Thank you! > > > > > > > > > > > > > > > > Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley escreveu: > > > > > > > > > > Hi Patricia > > > > > > > > > > > > The Stanozolol often has a side-effect of elevating liver enzymes, though I cannot remember if it also increased bilirubin (which would be what would cause the icteric observation of the plasma). However, hang in there. If it is the Stanozolol, my experience is that the liver enzymes drop right back to normal, shortly after it is discontinued, and there is no lasting damage to the liver. For now, what you have described (low temp and slightly lower heart rate) seems more likely to be related to the transfusion itself, rather than anything else going on. > > > > > > > > > > > > It is also possible that with the additional transfusion, there is a higher than normal red cell destruction going on, which would be another explanation for the increased icterus in the blood (which will also show as an increase in bilirubin). Elevated bilirubin can often be caused by a reaction to a blood transfusion. If the high bilirubin is the indirect or the unconjugated portion, it is related to red cell break down. The direct bilirubin (conjugated portion) is related to liver function. The lab results are usually broken down to Total bilirubin and Direct bilirubin. The indirect portion is obtained by subtracting the direct amount from the total amount. > > > > > > > > > > > > I myself went through the pressure of the vets wanting me to discontinue the Stanozolol because of abnormal liver enzymes. My logic was that there was nothing else. If I discontinued the Stanozolol, my cat would die, period. I continued and found that in the end, the liver enzymes normalized on their own, even though I had Zander on almost continuous Stanozolol for close to two years. > > > > > > > > > > > > I know that you know that you are only temporarily helping Nori with blood transfusions, and the virus is still attacking cells, etc. In my opinion ? and mine alone ? my experience and research leads me to the conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell production, but I believe that the Doxycyline assisted in keeping the viruses from properly reproducing. > > > > > > > > > > > > However, anticipate that when the vet gets back the second set of blood work, she may well try to tell you to discontinue the Stanozolol. > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > Sent: June 7, 2019 12:53 PM > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > Hi, Amani! > > > > > > > > > > > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > > > > > > > > > > > Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. > > > > > > > > > > > > But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? > > > > > > > > > > > > About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. > > > > > > > > > > > > i am worried again. > > > > > > > > > > > > Thank you, > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley escreveu: > > > > > > > > > > > > > > I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > Sent: June 4, 2019 8:53 PM > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > Hi, Lorraine > > > > > > > > > > > > > > > > Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. > > > > > > > > > > > > > > > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > > > > > > > > > > > > > > > We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > > > > > > > > > > > > > :( > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston escreveu: > > > > > > > > > > > > > > > > > > Patricia, > > > > > > > > > > > > > > > > > > > > I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. > > > > > > > > > > > > > > > > > > > > - Lorraine > > > > > > > > > > > > > > > > > > > > "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing > > > > > > > > > > > > > > > > > > > > From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org mailto:felvtalk-bounces at felineleukemia.org ] On Behalf Of Patricia Oliveira > > > > > Sent: Tuesday, June 4, 2019 6:34 PM > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > Hi, > > > > > > > > > > > > > > > > > > > > We did another blood work today, her hematocrit is 13% now :( > > > > > > > > > > > > > > > > > > > > She is very sleepy but responsive when i talk to her. > > > > > > > > > > > > > > > > > > > > I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. > > > > > > > > > > > > > > > > > > > > Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? > > > > > > > > > > > > > > > > > > > > Thank you, > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley escreveu: > > > > > > > > > > > > > > > > > > > > > > Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. > > > > > > > > > > > > > > > > > > > > > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. > > > > > > > > > > > > > > > > > > > > > > > > I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > Sent: June 1, 2019 12:36 PM > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > Hi, Amani! > > > > > > > > > > > > > > > > > > > > > > > > Thanky you very much for you email! > > > > > > > > > > > > > > > > > > > > > > > > Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. > > > > > > > > > > > > > > > > > > > > > > > > Today i bought other kinds of canned, i'll try them hoping she likes some one. > > > > > > > > > > > > > > > > > > > > > > > > Compound pharmacy must delivery stanozolol today. > > > > > > > > > > > > > > > > > > > > > > > > Are there any precautions regarding medication schedules? Close or far to doxy, for example? > > > > > > > > > > > > > > > > > > > > > > > > This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html?fbclid=IwAR0cXMedtfi73B81pJI7QiYGwRTJf9VJp-JN7S_Tstb0ANeg0Hm4ObtFH_A > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thank you! > > > > > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. > > > > > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > > Sent: May 30, 2019 12:56 PM > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > Subject: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi from Brazil, > > > > > > > > > > > > > > > > > > > > > > > > > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > > > > > > > > > > > > > > > > > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. > > > > > > > > > > > > > > She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. > > > > > > > > > > > > > > She also have changes in her kidneys. It has been tested and is felv + > > > > > > > > > > > > > > She is receiving doxy and the hospital vets would like to include prednisolone. > > > > > > > > > > > > > > However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. > > > > > > > > > > > > > > The veterinarian agreed to prescribe stanozolol. > > > > > > > > > > > > > > Can it be used without prednisolone, only with doxy she is already receiving? > > > > > > > > > > > > > > Thank you! > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From aoakley at oakleylegal.com Sat Jun 8 10:29:17 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Sat, 8 Jun 2019 15:29:17 +0000 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> Message-ID: I have never heard of this ?bizarre core? reference to neutrophils. It may be a term you guys use in your country but I cannot even guess what the equivalent might be here. It certainly sounds like Nori had a bit of a transfusion reaction this time. Hopefully, it will pass and she?ll feel better soon. Amani From: Felvtalk On Behalf Of Patricia Oliveira Sent: June 7, 2019 9:56 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Nori did not want to eat by herself so they are syringing food. They started another medication for nausea, although she does not vomit, they think that may be why she does not eat. Blood work showed changes in neutrophils (bizarre core?), veternary says it can be from leukemia. The result of this transfusion was not as good as the other time :( i?ll talk to veterinary tomorrow morning again. thank you! Patr?cia Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley > escreveu: Still sounds more like a transfusion reaction than anything with the meds. Hang in there. See what the afternoon labs show. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 1:44 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani Nori is receiving doxy+prenisolone+stanazolol even in the hospital. I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don?t remember if it was icteric plasma on last one. I was hopefull she would come back home tomorrow, now i don?t know if it will be possible. Today she must have am echocardiogram too because x-ray showed an enlarged heart. Thank you! Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: Hi Patricia The Stanozolol often has a side-effect of elevating liver enzymes, though I cannot remember if it also increased bilirubin (which would be what would cause the icteric observation of the plasma). However, hang in there. If it is the Stanozolol, my experience is that the liver enzymes drop right back to normal, shortly after it is discontinued, and there is no lasting damage to the liver. For now, what you have described (low temp and slightly lower heart rate) seems more likely to be related to the transfusion itself, rather than anything else going on. It is also possible that with the additional transfusion, there is a higher than normal red cell destruction going on, which would be another explanation for the increased icterus in the blood (which will also show as an increase in bilirubin). Elevated bilirubin can often be caused by a reaction to a blood transfusion. If the high bilirubin is the indirect or the unconjugated portion, it is related to red cell break down. The direct bilirubin (conjugated portion) is related to liver function. The lab results are usually broken down to Total bilirubin and Direct bilirubin. The indirect portion is obtained by subtracting the direct amount from the total amount. I myself went through the pressure of the vets wanting me to discontinue the Stanozolol because of abnormal liver enzymes. My logic was that there was nothing else. If I discontinued the Stanozolol, my cat would die, period. I continued and found that in the end, the liver enzymes normalized on their own, even though I had Zander on almost continuous Stanozolol for close to two years. I know that you know that you are only temporarily helping Nori with blood transfusions, and the virus is still attacking cells, etc. In my opinion ? and mine alone ? my experience and research leads me to the conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell production, but I believe that the Doxycyline assisted in keeping the viruses from properly reproducing. However, anticipate that when the vet gets back the second set of blood work, she may well try to tell you to discontinue the Stanozolol. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 12:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Nori got another transfusion last night, hematocrit was 11.9 before it. Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. i am worried again. Thank you, Patr?cia Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 4, 2019 8:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Lorraine Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). :( Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston > escreveu: Patricia, I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] On Behalf Of Patricia Oliveira Sent: Tuesday, June 4, 2019 6:34 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia -------------- next part -------------- An HTML attachment was scrubbed... URL: From emccarty44 at gmail.com Sat Jun 8 10:34:37 2019 From: emccarty44 at gmail.com (Liz Baumeister) Date: Sat, 8 Jun 2019 08:34:37 -0700 Subject: [Felvtalk] Felvtalk Digest, Vol 55, Issue 12 In-Reply-To: References: Message-ID: Please remove me from your mailing list On Sat, Jun 8, 2019, 8:29 AM wrote: > Send Felvtalk mailing list submissions to > felvtalk at felineleukemia.org > > To subscribe or unsubscribe via the World Wide Web, visit > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > or, via email, send a message with subject or body 'help' to > felvtalk-request at felineleukemia.org > > You can reach the person managing the list at > felvtalk-owner at felineleukemia.org > > When replying, please edit your Subject line so it is more specific > than "Re: Contents of Felvtalk digest..." > > > Today's Topics: > > 1. Re: Rescued kitten felv + (Amani Oakley) > > > ---------------------------------------------------------------------- > > Message: 1 > Date: Sat, 8 Jun 2019 15:29:17 +0000 > From: Amani Oakley > To: "felvtalk at felineleukemia.org" > Subject: Re: [Felvtalk] Rescued kitten felv + > Message-ID: > > > Content-Type: text/plain; charset="utf-8" > > I have never heard of this ?bizarre core? reference to neutrophils. It may > be a term you guys use in your country but I cannot even guess what the > equivalent might be here. > > It certainly sounds like Nori had a bit of a transfusion reaction this > time. Hopefully, it will pass and she?ll feel better soon. > > Amani > > From: Felvtalk On Behalf Of > Patricia Oliveira > Sent: June 7, 2019 9:56 PM > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > > Nori did not want to eat by herself so they are syringing food. They > started another medication for nausea, although she does not vomit, they > think that may be why she does not eat. > > Blood work showed changes in neutrophils (bizarre core?), veternary says > it can be from leukemia. > > The result of this transfusion was not as good as the other time :( > > i?ll talk to veterinary tomorrow morning again. > > thank you! > > Patr?cia > > > > Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley > escreveu: > Still sounds more like a transfusion reaction than anything with the meds. > > Hang in there. See what the afternoon labs show. > > Amani > > From: Felvtalk felvtalk-bounces at felineleukemia.org>> On Behalf Of Patricia Oliveira > Sent: June 7, 2019 1:44 PM > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > > Hi, Amani > > Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > > I know it can be a reaction but i thought higher dose of prednisolone > would prevent hemolysis. > > I also know it's normal for part of the red blood cells to be cleared > right after the transfusion, but i don?t remember if it was icteric plasma > on last one. > > I was hopefull she would come back home tomorrow, now i don?t know if it > will be possible. > > Today she must have am echocardiogram too because x-ray showed an enlarged > heart. > > Thank you! > > > > Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: > Hi Patricia > > The Stanozolol often has a side-effect of elevating liver enzymes, though > I cannot remember if it also increased bilirubin (which would be what would > cause the icteric observation of the plasma). However, hang in there. If it > is the Stanozolol, my experience is that the liver enzymes drop right back > to normal, shortly after it is discontinued, and there is no lasting damage > to the liver. For now, what you have described (low temp and slightly lower > heart rate) seems more likely to be related to the transfusion itself, > rather than anything else going on. > > It is also possible that with the additional transfusion, there is a > higher than normal red cell destruction going on, which would be another > explanation for the increased icterus in the blood (which will also show as > an increase in bilirubin). Elevated bilirubin can often be caused by a > reaction to a blood transfusion. If the high bilirubin is the indirect or > the unconjugated portion, it is related to red cell break down. The direct > bilirubin (conjugated portion) is related to liver function. The lab > results are usually broken down to Total bilirubin and Direct bilirubin. > The indirect portion is obtained by subtracting the direct amount from the > total amount. > > I myself went through the pressure of the vets wanting me to discontinue > the Stanozolol because of abnormal liver enzymes. My logic was that there > was nothing else. If I discontinued the Stanozolol, my cat would die, > period. I continued and found that in the end, the liver enzymes normalized > on their own, even though I had Zander on almost continuous Stanozolol for > close to two years. > > I know that you know that you are only temporarily helping Nori with blood > transfusions, and the virus is still attacking cells, etc. In my opinion ? > and mine alone ? my experience and research leads me to the conclusion that > the combination of Doxycycline/Prednisone/Stanozolol worked to not only > boost the red cell production, but I believe that the Doxycyline assisted > in keeping the viruses from properly reproducing. > > However, anticipate that when the vet gets back the second set of blood > work, she may well try to tell you to discontinue the Stanozolol. > > Amani > > > > From: Felvtalk felvtalk-bounces at felineleukemia.org>> On Behalf Of Patricia Oliveira > Sent: June 7, 2019 12:53 PM > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > > Hi, Amani! > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > Today morning, i talk to the hospital's veterinarian, she said hematocrit > went to 29 and Nori was fine, all normal parameters and eating by herself > again. > > But plasma was intensely icteric. I think this means red cells being > destroyed, isn't it? > > About one hour ago, veterinarian said Nori was with low temperature and > heart rate slightly lower than normal. She was waiting the new blood work. > In the morning, it was done only hematocrit, not complete blood work. > > i am worried again. > > Thank you, > > Patr?cia > > Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: > I would be leery of the going the route suggested by the vet at this > juncture. I seriously seriously doubt if the erythropoietin will help. See > my earlier where I explain why. > > Amani > > From: Felvtalk felvtalk-bounces at felineleukemia.org>> On Behalf Of Patricia Oliveira > Sent: June 4, 2019 8:53 PM > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > > Hi, Lorraine > > Veterinary wants to increase prednisolone to immunosuppressive dose and > add erythropoietin. She thinks it is immune-mediated anemia and not > mycoplasma. > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > We did x-ray today too. No visible tumor but we found a possible > cardiopathy ("Increased globular-looking heart silhouette"). > > :( > > > > Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < > johnston1110 at comcast.net> escreveu: > Patricia, > > I would go with the transfusion and also start erythropoietin. Stanozolol > is supposed to stimulate erythropoietin production, but she might need a > boost of the ready-made drug just to keep her alive until then. > > - Lorraine > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org felvtalk-bounces at felineleukemia.org>] On Behalf Of Patricia Oliveira > Sent: Tuesday, June 4, 2019 6:34 PM > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > > Hi, > > We did another blood work today, her hematocrit is 13% now :( > > She is very sleepy but responsive when i talk to her. > > I don?t know if i can wait some more days to see if stanozolol is working. > Or maybe it would be better get another transfusion right now. > > Today, vet talk about erythropoietin. Do you know if it can be used with > stanozolol? > > Thank you, > > Patr?cia > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: > Hi Patricia ? I gave all the pills together, morning and evening, except > for the metoclopramide which was given ? or so before meals. The rest I > gave with the meals. I didn?t observe a problem with giving them together. > > You might also try baby food to get Nori to eat. Get the pureed kind (beef > or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > Amani > > From: Felvtalk felvtalk-bounces at felineleukemia.org>> On Behalf Of Patricia Oliveira > Sent: June 1, 2019 12:36 PM > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > > Hi, Amani! > > Thanky you very much for you email! > > Nori was discharged from the hospital yesterday night. She is eating baby > dry food. I tried canned but she didn?t accept so weel. > > Today i bought other kinds of canned, i'll try them hoping she likes some > one. > > Compound pharmacy must delivery stanozolol today. > > Are there any precautions regarding medication schedules? Close or far to > doxy, for example? > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html< > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html?fbclid=IwAR0cXMedtfi73B81pJI7QiYGwRTJf9VJp-JN7S_Tstb0ANeg0Hm4ObtFH_A > > > > > Thank you! > > Patr?cia > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > Amani > > From: Felvtalk felvtalk-bounces at felineleukemia.org>> On Behalf Of Patricia Oliveira > Sent: May 30, 2019 12:56 PM > To: felvtalk at felineleukemia.org > Subject: [Felvtalk] Rescued kitten felv + > > Hi from Brazil, > > I rescued a very weak, dehydrated, extremely thin kitten. > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > Patr?cia > -------------- next part -------------- > An HTML attachment was scrubbed... > URL: < > http://felineleukemia.org/pipermail/felvtalk_felineleukemia.org/attachments/20190608/1b4a2356/attachment.html > > > > ------------------------------ > > Subject: Digest Footer > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > ------------------------------ > > End of Felvtalk Digest, Vol 55, Issue 12 > **************************************** > -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Sat Jun 8 19:22:29 2019 From: johnston1110 at comcast.net (Lorraine Johnston) Date: Sat, 8 Jun 2019 20:22:29 -0400 Subject: [Felvtalk] feline interferon omega ? Message-ID: <000a01d51e59$6ce7c970$46b75c50$@net> Is anyone here using feline interferon omega (FIO) for FeLV cats? Thank you, - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Sat Jun 8 19:51:46 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Sat, 8 Jun 2019 21:51:46 -0300 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: <1605332536.612607.1560004826102@connect.xfinity.com> References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> Message-ID: Thank you, Sandra :) I visited Nori today. The hospital is in another city so I can't go there every day. She is a rosy gingiva, but continues to sleep most of the time and with a low temperature. One of the veterinarians there thinks that temperature is lower because of malnutrition, she has almost no lean mass and no fat. Nori will go through the evaluation of a neurologist tomorrow. Some hypotheses raised for this prostration are neurological, including a possible hypoxia before the first transfusion when her hematocrit was really low. Her blood work today is 30% hematocrit, the higher till now! So i think red cells aren?t being destroyed anymore, is it right or is it early to know? Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low platelets for the first time (92.000). Nori had an echocardiogram today too and it is ok. Thank you! Patr?cia Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter < swacht1946 at comcast.net> escreveu: > Hello Patricia, you may already be doing this - but if not, please take a > copy of Amani's conversations for the vet to read - may help. > > Good luck - don't give up!! > > Sandt W > > > On June 7, 2019 at 9:55 PM Patricia Oliveira > wrote: > > Nori did not want to eat by herself so they are syringing food. They > started another medication for nausea, although she does not vomit, they > think that may be why she does not eat. > > Blood work showed changes in neutrophils (bizarre core?), veternary says > it can be from leukemia. > > The result of this transfusion was not as good as the other time :( > > i?ll talk to veterinary tomorrow morning again. > > thank you! > > Patr?cia > > > > Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com> > escreveu: > > Still sounds more like a transfusion reaction than anything with the meds. > > > > Hang in there. See what the afternoon labs show. > > > > Amani > > > > *From:* Felvtalk * On Behalf Of *Patricia > Oliveira > *Sent:* June 7, 2019 1:44 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani > > > > Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > > > > I know it can be a reaction but i thought higher dose of prednisolone > would prevent hemolysis. > > > > I also know it's normal for part of the red blood cells to be cleared > right after the transfusion, but i don?t remember if it was icteric plasma > on last one. > > > > I was hopefull she would come back home tomorrow, now i don?t know if it > will be possible. > > > > Today she must have am echocardiogram too because x-ray showed an enlarged > heart. > > > > Thank you! > > > > > > > > Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: > > Hi Patricia > > > > The Stanozolol often has a side-effect of elevating liver enzymes, though > I cannot remember if it also increased bilirubin (which would be what would > cause the icteric observation of the plasma). However, hang in there. If it > is the Stanozolol, my experience is that the liver enzymes drop right back > to normal, shortly after it is discontinued, and there is no lasting damage > to the liver. For now, what you have described (low temp and slightly lower > heart rate) seems more likely to be related to the transfusion itself, > rather than anything else going on. > > > > It is also possible that with the additional transfusion, there is a > higher than normal red cell destruction going on, which would be another > explanation for the increased icterus in the blood (which will also show as > an increase in bilirubin). Elevated bilirubin can often be caused by a > reaction to a blood transfusion. If the high bilirubin is the indirect or > the unconjugated portion, it is related to red cell break down. The direct > bilirubin (conjugated portion) is related to liver function. The lab > results are usually broken down to Total bilirubin and Direct bilirubin. > The indirect portion is obtained by subtracting the direct amount from the > total amount. > > > > I myself went through the pressure of the vets wanting me to discontinue > the Stanozolol because of abnormal liver enzymes. My logic was that there > was nothing else. If I discontinued the Stanozolol, my cat would die, > period. I continued and found that in the end, the liver enzymes normalized > on their own, even though I had Zander on almost continuous Stanozolol for > close to two years. > > > > I know that you know that you are only temporarily helping Nori with blood > transfusions, and the virus is still attacking cells, etc. In my opinion ? > and mine alone ? my experience and research leads me to the conclusion that > the combination of Doxycycline/Prednisone/Stanozolol worked to not only > boost the red cell production, but I believe that the Doxycyline assisted > in keeping the viruses from properly reproducing. > > > > However, anticipate that when the vet gets back the second set of blood > work, she may well try to tell you to discontinue the Stanozolol. > > > > Amani > > > > > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 7, 2019 12:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > > > Today morning, i talk to the hospital's veterinarian, she said hematocrit > went to 29 and Nori was fine, all normal parameters and eating by herself > again. > > > > But plasma was intensely icteric. I think this means red cells being > destroyed, isn't it? > > > > About one hour ago, veterinarian said Nori was with low temperature and > heart rate slightly lower than normal. She was waiting the new blood work. > In the morning, it was done only hematocrit, not complete blood work. > > > > i am worried again. > > > > Thank you, > > > > Patr?cia > > > > Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: > > I would be leery of the going the route suggested by the vet at this > juncture. I seriously seriously doubt if the erythropoietin will help. See > my earlier where I explain why. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 4, 2019 8:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Lorraine > > > > Veterinary wants to increase prednisolone to immunosuppressive dose and > add erythropoietin. She thinks it is immune-mediated anemia and > not mycoplasma. > > > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > > > We did x-ray today too. No visible tumor but we found a > possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > :( > > > > > > > > Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < > johnston1110 at comcast.net> escreveu: > > Patricia, > > > > I would go with the transfusion and also start erythropoietin. Stanozolol > is supposed to stimulate erythropoietin production, but she might need a > boost of the ready-made drug just to keep her alive until then. > > > > - Lorraine > > > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > > > *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On Behalf > Of *Patricia Oliveira > *Sent:* Tuesday, June 4, 2019 6:34 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, > > > > We did another blood work today, her hematocrit is 13% now :( > > > > She is very sleepy but responsive when i talk to her. > > > > I don?t know if i can wait some more days to see if stanozolol is working. > Or maybe it would be better get another transfusion right now. > > > > Today, vet talk about erythropoietin. Do you know if it can be used with > stanozolol? > > > > Thank you, > > > > Patr?cia > > > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: > > Hi Patricia ? I gave all the pills together, morning and evening, except > for the metoclopramide which was given ? or so before meals. The rest I > gave with the meals. I didn?t observe a problem with giving them together. > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef > or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 1, 2019 12:36 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Thanky you very much for you email! > > > > Nori was discharged from the hospital yesterday night. She is eating baby > dry food. I tried canned but she didn?t accept so weel. > > > > Today i bought other kinds of canned, i'll try them hoping she likes some > one. > > > > Compound pharmacy must delivery stanozolol today. > > > > Are there any precautions regarding medication schedules? Close or far to > doxy, for example? > > > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > > > > > > > Thank you! > > > > Patr?cia > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: > > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* May 30, 2019 12:56 PM > *To:* felvtalk at felineleukemia.org > *Subject:* [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > > > Patr?cia > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From aoakley at oakleylegal.com Sat Jun 8 20:03:28 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Sun, 9 Jun 2019 01:03:28 +0000 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> Message-ID: Patricia I agree with you that it is too early to tell, but for sure it is good news that the haematocrit is moving in the right direction. Very good news on the rosy gingiva. Rouleaux is likely only due to the transfusion. She appears to have had a bit of transfusion reaction, so the cells may be sticking to one another as a result. (Red cells in Rouleaux formation means that the look like a stack of coins ? one on top of the other. In humans, that presentation is consistent with multiple myeloma. I don?t think it means anything right now other than the new red cells may be reacting a bit with her own cells). I think she is working through the transfusion reaction, so that is likely why she is sleeping because you said that immediately after the transfusion, she was active and eating on her own. Low platelets are consistent with the FeLV presentation and the impact on the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that with my Zander, I had the red cell numbers recover first, before the platelets recovered. I presume they have her on a heating pad to keep her body temperature up. I suspect it might be premature to look at the neurology right now. She is working through a lot, and is a tiny kitten. She needs to be given time to recover from the transfusion reaction, and to allow the good food and medication to start to work. I don?t know how a neurological diagnosis could help you now, and one would expect the neurologist will have a difficult time seeing a true neurological deficit, with all the rest of the stuff happening. I would also suggest that at some point, it is better for her to be with you at home. If they are not giving her anything like fluids, you might consider taking her home with you. I know with Zander, he reacted most strongly when I was there with him. I could get him to play a little bit and that made him feel better, and of course, lots of cuddles and kisses. Amani From: Felvtalk On Behalf Of Patricia Oliveira Sent: June 8, 2019 8:52 PM To: Sandra Wachtstetter ; felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Thank you, Sandra :) I visited Nori today. The hospital is in another city so I can't go there every day. She is a rosy gingiva, but continues to sleep most of the time and with a low temperature. One of the veterinarians there thinks that temperature is lower because of malnutrition, she has almost no lean mass and no fat. Nori will go through the evaluation of a neurologist tomorrow. Some hypotheses raised for this prostration are neurological, including a possible hypoxia before the first transfusion when her hematocrit was really low. Her blood work today is 30% hematocrit, the higher till now! So i think red cells aren?t being destroyed anymore, is it right or is it early to know? Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low platelets for the first time (92.000). Nori had an echocardiogram today too and it is ok. Thank you! Patr?cia Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter > escreveu: Hello Patricia, you may already be doing this - but if not, please take a copy of Amani's conversations for the vet to read - may help. Good luck - don't give up!! Sandt W On June 7, 2019 at 9:55 PM Patricia Oliveira > wrote: Nori did not want to eat by herself so they are syringing food. They started another medication for nausea, although she does not vomit, they think that may be why she does not eat. Blood work showed changes in neutrophils (bizarre core?), veternary says it can be from leukemia. The result of this transfusion was not as good as the other time :( i?ll talk to veterinary tomorrow morning again. thank you! Patr?cia Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com> escreveu: Still sounds more like a transfusion reaction than anything with the meds. Hang in there. See what the afternoon labs show. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 1:44 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani Nori is receiving doxy+prenisolone+stanazolol even in the hospital. I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don?t remember if it was icteric plasma on last one. I was hopefull she would come back home tomorrow, now i don?t know if it will be possible. Today she must have am echocardiogram too because x-ray showed an enlarged heart. Thank you! Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: Hi Patricia The Stanozolol often has a side-effect of elevating liver enzymes, though I cannot remember if it also increased bilirubin (which would be what would cause the icteric observation of the plasma). However, hang in there. If it is the Stanozolol, my experience is that the liver enzymes drop right back to normal, shortly after it is discontinued, and there is no lasting damage to the liver. For now, what you have described (low temp and slightly lower heart rate) seems more likely to be related to the transfusion itself, rather than anything else going on. It is also possible that with the additional transfusion, there is a higher than normal red cell destruction going on, which would be another explanation for the increased icterus in the blood (which will also show as an increase in bilirubin). Elevated bilirubin can often be caused by a reaction to a blood transfusion. If the high bilirubin is the indirect or the unconjugated portion, it is related to red cell break down. The direct bilirubin (conjugated portion) is related to liver function. The lab results are usually broken down to Total bilirubin and Direct bilirubin. The indirect portion is obtained by subtracting the direct amount from the total amount. I myself went through the pressure of the vets wanting me to discontinue the Stanozolol because of abnormal liver enzymes. My logic was that there was nothing else. If I discontinued the Stanozolol, my cat would die, period. I continued and found that in the end, the liver enzymes normalized on their own, even though I had Zander on almost continuous Stanozolol for close to two years. I know that you know that you are only temporarily helping Nori with blood transfusions, and the virus is still attacking cells, etc. In my opinion ? and mine alone ? my experience and research leads me to the conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell production, but I believe that the Doxycyline assisted in keeping the viruses from properly reproducing. However, anticipate that when the vet gets back the second set of blood work, she may well try to tell you to discontinue the Stanozolol. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 12:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Nori got another transfusion last night, hematocrit was 11.9 before it. Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. i am worried again. Thank you, Patr?cia Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 4, 2019 8:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Lorraine Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). :( Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston > escreveu: Patricia, I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] On Behalf Of Patricia Oliveira Sent: Tuesday, June 4, 2019 6:34 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Sat Jun 8 20:53:19 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Sat, 8 Jun 2019 22:53:19 -0300 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> Message-ID: She has fluids IV all the time and replenishment of potassium. Receives external heating too. They monitor pressure (low sometimes), oxygenation, temperature and heart rate several times a day. I wish she could come home soon but she has been dehydrated even with fluids IV. I don?t know if it is safe to bring her now. Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley escreveu: > Patricia > > > > I agree with you that it is too early to tell, but for sure it is good > news that the haematocrit is moving in the right direction. Very good news > on the rosy gingiva. > > > > Rouleaux is likely only due to the transfusion. She appears to have had a > bit of transfusion reaction, so the cells may be sticking to one another as > a result. (Red cells in Rouleaux formation means that the look like a stack > of coins ? one on top of the other. In humans, that presentation is > consistent with multiple myeloma. I don?t think it means anything right now > other than the new red cells may be reacting a bit with her own cells). > > > > I think she is working through the transfusion reaction, so that is likely > why she is sleeping because you said that immediately after the > transfusion, she was active and eating on her own. > > > > Low platelets are consistent with the FeLV presentation and the impact on > the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that > with my Zander, I had the red cell numbers recover first, before the > platelets recovered. > > > > I presume they have her on a heating pad to keep her body temperature up. > > > > I suspect it might be premature to look at the neurology right now. She is > working through a lot, and is a tiny kitten. She needs to be given time to > recover from the transfusion reaction, and to allow the good food and > medication to start to work. I don?t know how a neurological diagnosis > could help you now, and one would expect the neurologist will have a > difficult time seeing a true neurological deficit, with all the rest of the > stuff happening. > > > > I would also suggest that at some point, it is better for her to be with > you at home. If they are not giving her anything like fluids, you might > consider taking her home with you. I know with Zander, he reacted most > strongly when I was there with him. I could get him to play a little bit > and that made him feel better, and of course, lots of cuddles and kisses. > > > > Amani > > > > *From:* Felvtalk * On Behalf Of *Patricia > Oliveira > *Sent:* June 8, 2019 8:52 PM > *To:* Sandra Wachtstetter ; > felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Thank you, Sandra :) > > > > I visited Nori today. The hospital is in another city so I can't go there > every day. > > > > She is a rosy gingiva, but continues to sleep most of the time and with a > low temperature. One of the veterinarians there thinks that temperature is > lower because of malnutrition, she has almost no lean mass and no fat. > > > > Nori will go through the evaluation of a neurologist tomorrow. Some > hypotheses raised for this prostration are neurological, including a > possible hypoxia before the first transfusion when her hematocrit was > really low. > > > > Her blood work today is 30% hematocrit, the higher till now! So i think > red cells aren?t being destroyed anymore, is it right or is it early to > know? > > > > Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low > platelets for the first time (92.000). > > > > Nori had an echocardiogram today too and it is ok. > > > > Thank you! > > > > Patr?cia > > > > Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter < > swacht1946 at comcast.net> escreveu: > > Hello Patricia, you may already be doing this - but if not, please take a > copy of Amani's conversations for the vet to read - may help. > > Good luck - don't give up!! > > Sandt W > > > > On June 7, 2019 at 9:55 PM Patricia Oliveira > wrote: > > Nori did not want to eat by herself so they are syringing food. They > started another medication for nausea, although she does not vomit, they > think that may be why she does not eat. > > > > Blood work showed changes in neutrophils (bizarre core?), veternary says > it can be from leukemia. > > > > The result of this transfusion was not as good as the other time :( > > > > i?ll talk to veterinary tomorrow morning again. > > > > thank you! > > > > Patr?cia > > > > > > > > Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com> > escreveu: > > Still sounds more like a transfusion reaction than anything with the meds. > > > > Hang in there. See what the afternoon labs show. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 7, 2019 1:44 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani > > > > Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > > > > I know it can be a reaction but i thought higher dose of prednisolone > would prevent hemolysis. > > > > I also know it's normal for part of the red blood cells to be cleared > right after the transfusion, but i don?t remember if it was icteric plasma > on last one. > > > > I was hopefull she would come back home tomorrow, now i don?t know if it > will be possible. > > > > Today she must have am echocardiogram too because x-ray showed an enlarged > heart. > > > > Thank you! > > > > > > > > Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: > > Hi Patricia > > > > The Stanozolol often has a side-effect of elevating liver enzymes, though > I cannot remember if it also increased bilirubin (which would be what would > cause the icteric observation of the plasma). However, hang in there. If it > is the Stanozolol, my experience is that the liver enzymes drop right back > to normal, shortly after it is discontinued, and there is no lasting damage > to the liver. For now, what you have described (low temp and slightly lower > heart rate) seems more likely to be related to the transfusion itself, > rather than anything else going on. > > > > It is also possible that with the additional transfusion, there is a > higher than normal red cell destruction going on, which would be another > explanation for the increased icterus in the blood (which will also show as > an increase in bilirubin). Elevated bilirubin can often be caused by a > reaction to a blood transfusion. If the high bilirubin is the indirect or > the unconjugated portion, it is related to red cell break down. The direct > bilirubin (conjugated portion) is related to liver function. The lab > results are usually broken down to Total bilirubin and Direct bilirubin. > The indirect portion is obtained by subtracting the direct amount from the > total amount. > > > > I myself went through the pressure of the vets wanting me to discontinue > the Stanozolol because of abnormal liver enzymes. My logic was that there > was nothing else. If I discontinued the Stanozolol, my cat would die, > period. I continued and found that in the end, the liver enzymes normalized > on their own, even though I had Zander on almost continuous Stanozolol for > close to two years. > > > > I know that you know that you are only temporarily helping Nori with blood > transfusions, and the virus is still attacking cells, etc. In my opinion ? > and mine alone ? my experience and research leads me to the conclusion that > the combination of Doxycycline/Prednisone/Stanozolol worked to not only > boost the red cell production, but I believe that the Doxycyline assisted > in keeping the viruses from properly reproducing. > > > > However, anticipate that when the vet gets back the second set of blood > work, she may well try to tell you to discontinue the Stanozolol. > > > > Amani > > > > > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 7, 2019 12:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > > > Today morning, i talk to the hospital's veterinarian, she said hematocrit > went to 29 and Nori was fine, all normal parameters and eating by herself > again. > > > > But plasma was intensely icteric. I think this means red cells being > destroyed, isn't it? > > > > About one hour ago, veterinarian said Nori was with low temperature and > heart rate slightly lower than normal. She was waiting the new blood work. > In the morning, it was done only hematocrit, not complete blood work. > > > > i am worried again. > > > > Thank you, > > > > Patr?cia > > > > Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: > > I would be leery of the going the route suggested by the vet at this > juncture. I seriously seriously doubt if the erythropoietin will help. See > my earlier where I explain why. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 4, 2019 8:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Lorraine > > > > Veterinary wants to increase prednisolone to immunosuppressive dose and > add erythropoietin. She thinks it is immune-mediated anemia and > not mycoplasma. > > > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > > > We did x-ray today too. No visible tumor but we found a > possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > :( > > > > > > > > Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < > johnston1110 at comcast.net> escreveu: > > Patricia, > > > > I would go with the transfusion and also start erythropoietin. Stanozolol > is supposed to stimulate erythropoietin production, but she might need a > boost of the ready-made drug just to keep her alive until then. > > > > - Lorraine > > > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > > > *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On Behalf > Of *Patricia Oliveira > *Sent:* Tuesday, June 4, 2019 6:34 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, > > > > We did another blood work today, her hematocrit is 13% now :( > > > > She is very sleepy but responsive when i talk to her. > > > > I don?t know if i can wait some more days to see if stanozolol is working. > Or maybe it would be better get another transfusion right now. > > > > Today, vet talk about erythropoietin. Do you know if it can be used with > stanozolol? > > > > Thank you, > > > > Patr?cia > > > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: > > Hi Patricia ? I gave all the pills together, morning and evening, except > for the metoclopramide which was given ? or so before meals. The rest I > gave with the meals. I didn?t observe a problem with giving them together. > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef > or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 1, 2019 12:36 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Thanky you very much for you email! > > > > Nori was discharged from the hospital yesterday night. She is eating baby > dry food. I tried canned but she didn?t accept so weel. > > > > Today i bought other kinds of canned, i'll try them hoping she likes some > one. > > > > Compound pharmacy must delivery stanozolol today. > > > > Are there any precautions regarding medication schedules? Close or far to > doxy, for example? > > > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > > > > > > > Thank you! > > > > Patr?cia > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: > > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* May 30, 2019 12:56 PM > *To:* felvtalk at felineleukemia.org > *Subject:* [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > > > Patr?cia > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From aoakley at oakleylegal.com Sat Jun 8 21:23:19 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Sun, 9 Jun 2019 02:23:19 +0000 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> Message-ID: One option is to ask your vet to show you how to give her subcutaneous fluids, which I do all the time for my cats if needed. However, for now, it makes sense to leave her there I guess. I presume they are warming the IV fluids too, because again, with such a small kitten, it wouldn?t take much to chill her if the fluids are at room temperature or colder. I guess it?s just me. I am pretty adamant about taking home my cats whenever possible, but I understand that Nori sounds like she needs some extra help. I just find that the cats respond far better to personal cuddling and love, and this makes them feel better, eat more, etc. Hopefully, she will feel better tomorrow. I?m crossing my fingers for you and Nori. Amani From: Felvtalk On Behalf Of Patricia Oliveira Sent: June 8, 2019 9:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + She has fluids IV all the time and replenishment of potassium. Receives external heating too. They monitor pressure (low sometimes), oxygenation, temperature and heart rate several times a day. I wish she could come home soon but she has been dehydrated even with fluids IV. I don?t know if it is safe to bring her now. Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley > escreveu: Patricia I agree with you that it is too early to tell, but for sure it is good news that the haematocrit is moving in the right direction. Very good news on the rosy gingiva. Rouleaux is likely only due to the transfusion. She appears to have had a bit of transfusion reaction, so the cells may be sticking to one another as a result. (Red cells in Rouleaux formation means that the look like a stack of coins ? one on top of the other. In humans, that presentation is consistent with multiple myeloma. I don?t think it means anything right now other than the new red cells may be reacting a bit with her own cells). I think she is working through the transfusion reaction, so that is likely why she is sleeping because you said that immediately after the transfusion, she was active and eating on her own. Low platelets are consistent with the FeLV presentation and the impact on the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that with my Zander, I had the red cell numbers recover first, before the platelets recovered. I presume they have her on a heating pad to keep her body temperature up. I suspect it might be premature to look at the neurology right now. She is working through a lot, and is a tiny kitten. She needs to be given time to recover from the transfusion reaction, and to allow the good food and medication to start to work. I don?t know how a neurological diagnosis could help you now, and one would expect the neurologist will have a difficult time seeing a true neurological deficit, with all the rest of the stuff happening. I would also suggest that at some point, it is better for her to be with you at home. If they are not giving her anything like fluids, you might consider taking her home with you. I know with Zander, he reacted most strongly when I was there with him. I could get him to play a little bit and that made him feel better, and of course, lots of cuddles and kisses. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 8, 2019 8:52 PM To: Sandra Wachtstetter >; felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Thank you, Sandra :) I visited Nori today. The hospital is in another city so I can't go there every day. She is a rosy gingiva, but continues to sleep most of the time and with a low temperature. One of the veterinarians there thinks that temperature is lower because of malnutrition, she has almost no lean mass and no fat. Nori will go through the evaluation of a neurologist tomorrow. Some hypotheses raised for this prostration are neurological, including a possible hypoxia before the first transfusion when her hematocrit was really low. Her blood work today is 30% hematocrit, the higher till now! So i think red cells aren?t being destroyed anymore, is it right or is it early to know? Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low platelets for the first time (92.000). Nori had an echocardiogram today too and it is ok. Thank you! Patr?cia Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter > escreveu: Hello Patricia, you may already be doing this - but if not, please take a copy of Amani's conversations for the vet to read - may help. Good luck - don't give up!! Sandt W On June 7, 2019 at 9:55 PM Patricia Oliveira > wrote: Nori did not want to eat by herself so they are syringing food. They started another medication for nausea, although she does not vomit, they think that may be why she does not eat. Blood work showed changes in neutrophils (bizarre core?), veternary says it can be from leukemia. The result of this transfusion was not as good as the other time :( i?ll talk to veterinary tomorrow morning again. thank you! Patr?cia Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com> escreveu: Still sounds more like a transfusion reaction than anything with the meds. Hang in there. See what the afternoon labs show. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 1:44 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani Nori is receiving doxy+prenisolone+stanazolol even in the hospital. I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don?t remember if it was icteric plasma on last one. I was hopefull she would come back home tomorrow, now i don?t know if it will be possible. Today she must have am echocardiogram too because x-ray showed an enlarged heart. Thank you! Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: Hi Patricia The Stanozolol often has a side-effect of elevating liver enzymes, though I cannot remember if it also increased bilirubin (which would be what would cause the icteric observation of the plasma). However, hang in there. If it is the Stanozolol, my experience is that the liver enzymes drop right back to normal, shortly after it is discontinued, and there is no lasting damage to the liver. For now, what you have described (low temp and slightly lower heart rate) seems more likely to be related to the transfusion itself, rather than anything else going on. It is also possible that with the additional transfusion, there is a higher than normal red cell destruction going on, which would be another explanation for the increased icterus in the blood (which will also show as an increase in bilirubin). Elevated bilirubin can often be caused by a reaction to a blood transfusion. If the high bilirubin is the indirect or the unconjugated portion, it is related to red cell break down. The direct bilirubin (conjugated portion) is related to liver function. The lab results are usually broken down to Total bilirubin and Direct bilirubin. The indirect portion is obtained by subtracting the direct amount from the total amount. I myself went through the pressure of the vets wanting me to discontinue the Stanozolol because of abnormal liver enzymes. My logic was that there was nothing else. If I discontinued the Stanozolol, my cat would die, period. I continued and found that in the end, the liver enzymes normalized on their own, even though I had Zander on almost continuous Stanozolol for close to two years. I know that you know that you are only temporarily helping Nori with blood transfusions, and the virus is still attacking cells, etc. In my opinion ? and mine alone ? my experience and research leads me to the conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell production, but I believe that the Doxycyline assisted in keeping the viruses from properly reproducing. However, anticipate that when the vet gets back the second set of blood work, she may well try to tell you to discontinue the Stanozolol. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 12:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Nori got another transfusion last night, hematocrit was 11.9 before it. Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. i am worried again. Thank you, Patr?cia Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 4, 2019 8:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Lorraine Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). :( Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston > escreveu: Patricia, I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] On Behalf Of Patricia Oliveira Sent: Tuesday, June 4, 2019 6:34 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Sun Jun 9 11:21:05 2019 From: johnston1110 at comcast.net (Lorraine Johnston) Date: Sun, 9 Jun 2019 12:21:05 -0400 Subject: [Felvtalk] more re feline interferon omega Message-ID: <006b01d51edf$570fef20$052fcd60$@net> I see that feline interferon omega was discussed here a number of years ago. Below is recent information about feline interferon omega, shared by a biologist who is a member of another feline discussion group. Feline interferon omega is different from human interferon alfa, which will eventually cause a serious reaction if injected into a cat (though I?m told it can be used orally to control mouth sores with no risk of a reaction). - Lorraine . . . . . . . . . . . . . . . ?The European Veterinary Advisory Board on Cat Diseases recommends to treat FELV-infected cats with recurring infections as follows : ?Treat recurring infections aggressively (e.g., longer courses of and/or bacteriocidal antibiotics). Consider treatment with feline interferon-omega (106 IU/kg SQ q 24 h for 5 consecutive days, 3 courses starting on days 0, 14 and 60)? " ?They note in their Table 3 that injectable Feline Omega Interferon showed "efficacy in vivo," on FELV+ cats; that is it showed ?some effects (most likely more on secondary infections,? in properly designed studies by de Mari et al. (2004) and Gil et al. (2013). They note also in their Table 3 that subcutaneous or oral Human interferon alpha was ineffective in in vivo studies on FELV+ cats.? ?http://www.abcdcatsvets.org/feline-leukaemia-virus-infection/? (end quote) -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Sun Jun 9 13:09:27 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Sun, 9 Jun 2019 15:09:27 -0300 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> Message-ID: Hi! I have experience with subqs. Nori is really better today! She ate 2 dishes of wet food while i was there. She is more active and attentive to what happens. Neurologist said Nori has a deficiency on the left side of the body, as if she had a stroke. It can be because of anemia, an inflammation or even malnutrition. Vet added a brain supplement (MCT's) to Nori's prescription. Fip isn't discarded but felv also justify this condition so I hope she has nothing more. Vets said maybe Nori can come home tomorrow :) Thank you! Patr?cia Em s?b, 8 de jun de 2019 ?s 23:23, Amani Oakley escreveu: > One option is to ask your vet to show you how to give her subcutaneous > fluids, which I do all the time for my cats if needed. However, for now, it > makes sense to leave her there I guess. I presume they are warming the IV > fluids too, because again, with such a small kitten, it wouldn?t take much > to chill her if the fluids are at room temperature or colder. > > > > I guess it?s just me. I am pretty adamant about taking home my cats > whenever possible, but I understand that Nori sounds like she needs some > extra help. I just find that the cats respond far better to personal > cuddling and love, and this makes them feel better, eat more, etc. > > > > Hopefully, she will feel better tomorrow. > > > > I?m crossing my fingers for you and Nori. > > > > Amani > > > > *From:* Felvtalk * On Behalf Of *Patricia > Oliveira > *Sent:* June 8, 2019 9:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > She has fluids IV all the time and replenishment of potassium. Receives > external heating too. > > > > They monitor pressure (low sometimes), oxygenation, temperature and heart > rate several times a day. > > I wish she could come home soon but she has been dehydrated even with > fluids IV. I don?t know if it is safe to bring her now. > > > > > > > > Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley > escreveu: > > Patricia > > > > I agree with you that it is too early to tell, but for sure it is good > news that the haematocrit is moving in the right direction. Very good news > on the rosy gingiva. > > > > Rouleaux is likely only due to the transfusion. She appears to have had a > bit of transfusion reaction, so the cells may be sticking to one another as > a result. (Red cells in Rouleaux formation means that the look like a stack > of coins ? one on top of the other. In humans, that presentation is > consistent with multiple myeloma. I don?t think it means anything right now > other than the new red cells may be reacting a bit with her own cells). > > > > I think she is working through the transfusion reaction, so that is likely > why she is sleeping because you said that immediately after the > transfusion, she was active and eating on her own. > > > > Low platelets are consistent with the FeLV presentation and the impact on > the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that > with my Zander, I had the red cell numbers recover first, before the > platelets recovered. > > > > I presume they have her on a heating pad to keep her body temperature up. > > > > I suspect it might be premature to look at the neurology right now. She is > working through a lot, and is a tiny kitten. She needs to be given time to > recover from the transfusion reaction, and to allow the good food and > medication to start to work. I don?t know how a neurological diagnosis > could help you now, and one would expect the neurologist will have a > difficult time seeing a true neurological deficit, with all the rest of the > stuff happening. > > > > I would also suggest that at some point, it is better for her to be with > you at home. If they are not giving her anything like fluids, you might > consider taking her home with you. I know with Zander, he reacted most > strongly when I was there with him. I could get him to play a little bit > and that made him feel better, and of course, lots of cuddles and kisses. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 8, 2019 8:52 PM > *To:* Sandra Wachtstetter ; > felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Thank you, Sandra :) > > > > I visited Nori today. The hospital is in another city so I can't go there > every day. > > > > She is a rosy gingiva, but continues to sleep most of the time and with a > low temperature. One of the veterinarians there thinks that temperature is > lower because of malnutrition, she has almost no lean mass and no fat. > > > > Nori will go through the evaluation of a neurologist tomorrow. Some > hypotheses raised for this prostration are neurological, including a > possible hypoxia before the first transfusion when her hematocrit was > really low. > > > > Her blood work today is 30% hematocrit, the higher till now! So i think > red cells aren?t being destroyed anymore, is it right or is it early to > know? > > > > Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low > platelets for the first time (92.000). > > > > Nori had an echocardiogram today too and it is ok. > > > > Thank you! > > > > Patr?cia > > > > Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter < > swacht1946 at comcast.net> escreveu: > > Hello Patricia, you may already be doing this - but if not, please take a > copy of Amani's conversations for the vet to read - may help. > > Good luck - don't give up!! > > Sandt W > > > > On June 7, 2019 at 9:55 PM Patricia Oliveira > wrote: > > Nori did not want to eat by herself so they are syringing food. They > started another medication for nausea, although she does not vomit, they > think that may be why she does not eat. > > > > Blood work showed changes in neutrophils (bizarre core?), veternary says > it can be from leukemia. > > > > The result of this transfusion was not as good as the other time :( > > > > i?ll talk to veterinary tomorrow morning again. > > > > thank you! > > > > Patr?cia > > > > > > > > Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com> > escreveu: > > Still sounds more like a transfusion reaction than anything with the meds. > > > > Hang in there. See what the afternoon labs show. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 7, 2019 1:44 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani > > > > Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > > > > I know it can be a reaction but i thought higher dose of prednisolone > would prevent hemolysis. > > > > I also know it's normal for part of the red blood cells to be cleared > right after the transfusion, but i don?t remember if it was icteric plasma > on last one. > > > > I was hopefull she would come back home tomorrow, now i don?t know if it > will be possible. > > > > Today she must have am echocardiogram too because x-ray showed an enlarged > heart. > > > > Thank you! > > > > > > > > Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: > > Hi Patricia > > > > The Stanozolol often has a side-effect of elevating liver enzymes, though > I cannot remember if it also increased bilirubin (which would be what would > cause the icteric observation of the plasma). However, hang in there. If it > is the Stanozolol, my experience is that the liver enzymes drop right back > to normal, shortly after it is discontinued, and there is no lasting damage > to the liver. For now, what you have described (low temp and slightly lower > heart rate) seems more likely to be related to the transfusion itself, > rather than anything else going on. > > > > It is also possible that with the additional transfusion, there is a > higher than normal red cell destruction going on, which would be another > explanation for the increased icterus in the blood (which will also show as > an increase in bilirubin). Elevated bilirubin can often be caused by a > reaction to a blood transfusion. If the high bilirubin is the indirect or > the unconjugated portion, it is related to red cell break down. The direct > bilirubin (conjugated portion) is related to liver function. The lab > results are usually broken down to Total bilirubin and Direct bilirubin. > The indirect portion is obtained by subtracting the direct amount from the > total amount. > > > > I myself went through the pressure of the vets wanting me to discontinue > the Stanozolol because of abnormal liver enzymes. My logic was that there > was nothing else. If I discontinued the Stanozolol, my cat would die, > period. I continued and found that in the end, the liver enzymes normalized > on their own, even though I had Zander on almost continuous Stanozolol for > close to two years. > > > > I know that you know that you are only temporarily helping Nori with blood > transfusions, and the virus is still attacking cells, etc. In my opinion ? > and mine alone ? my experience and research leads me to the conclusion that > the combination of Doxycycline/Prednisone/Stanozolol worked to not only > boost the red cell production, but I believe that the Doxycyline assisted > in keeping the viruses from properly reproducing. > > > > However, anticipate that when the vet gets back the second set of blood > work, she may well try to tell you to discontinue the Stanozolol. > > > > Amani > > > > > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 7, 2019 12:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > > > Today morning, i talk to the hospital's veterinarian, she said hematocrit > went to 29 and Nori was fine, all normal parameters and eating by herself > again. > > > > But plasma was intensely icteric. I think this means red cells being > destroyed, isn't it? > > > > About one hour ago, veterinarian said Nori was with low temperature and > heart rate slightly lower than normal. She was waiting the new blood work. > In the morning, it was done only hematocrit, not complete blood work. > > > > i am worried again. > > > > Thank you, > > > > Patr?cia > > > > Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: > > I would be leery of the going the route suggested by the vet at this > juncture. I seriously seriously doubt if the erythropoietin will help. See > my earlier where I explain why. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 4, 2019 8:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Lorraine > > > > Veterinary wants to increase prednisolone to immunosuppressive dose and > add erythropoietin. She thinks it is immune-mediated anemia and > not mycoplasma. > > > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > > > We did x-ray today too. No visible tumor but we found a > possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > :( > > > > > > > > Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < > johnston1110 at comcast.net> escreveu: > > Patricia, > > > > I would go with the transfusion and also start erythropoietin. Stanozolol > is supposed to stimulate erythropoietin production, but she might need a > boost of the ready-made drug just to keep her alive until then. > > > > - Lorraine > > > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > > > *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On Behalf > Of *Patricia Oliveira > *Sent:* Tuesday, June 4, 2019 6:34 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, > > > > We did another blood work today, her hematocrit is 13% now :( > > > > She is very sleepy but responsive when i talk to her. > > > > I don?t know if i can wait some more days to see if stanozolol is working. > Or maybe it would be better get another transfusion right now. > > > > Today, vet talk about erythropoietin. Do you know if it can be used with > stanozolol? > > > > Thank you, > > > > Patr?cia > > > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: > > Hi Patricia ? I gave all the pills together, morning and evening, except > for the metoclopramide which was given ? or so before meals. The rest I > gave with the meals. I didn?t observe a problem with giving them together. > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef > or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 1, 2019 12:36 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Thanky you very much for you email! > > > > Nori was discharged from the hospital yesterday night. She is eating baby > dry food. I tried canned but she didn?t accept so weel. > > > > Today i bought other kinds of canned, i'll try them hoping she likes some > one. > > > > Compound pharmacy must delivery stanozolol today. > > > > Are there any precautions regarding medication schedules? Close or far to > doxy, for example? > > > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > > > > > > > Thank you! > > > > Patr?cia > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: > > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* May 30, 2019 12:56 PM > *To:* felvtalk at felineleukemia.org > *Subject:* [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > > > Patr?cia > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Sun Jun 9 17:26:42 2019 From: johnston1110 at comcast.net (Lorraine Johnston) Date: Sun, 9 Jun 2019 18:26:42 -0400 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> Message-ID: <002d01d51f12$703e6f70$50bb4e50$@net> Excellent news about Nori! - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] On Behalf Of Patricia Oliveira Sent: Sunday, June 9, 2019 2:09 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi! I have experience with subqs. Nori is really better today! She ate 2 dishes of wet food while i was there. She is more active and attentive to what happens. Neurologist said Nori has a deficiency on the left side of the body, as if she had a stroke. It can be because of anemia, an inflammation or even malnutrition. Vet added a brain supplement (MCT's) to Nori's prescription. Fip isn't discarded but felv also justify this condition so I hope she has nothing more. Vets said maybe Nori can come home tomorrow :) Thank you! Patr?cia -------------- next part -------------- An HTML attachment was scrubbed... URL: From thyme2sail at gmail.com Sun Jun 9 19:07:43 2019 From: thyme2sail at gmail.com (Pam Doore) Date: Sun, 9 Jun 2019 20:07:43 -0400 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> Message-ID: That is great news about Nori! ~~@~~~~~@~~~~~@~~~~~@~~~~~@~~~~ *Christ beside me, Christ before me, Christ behind me, Christ within me, Christ beneath me, Christ above me. ? **St. Patrick* On Sun, Jun 9, 2019 at 2:10 PM Patricia Oliveira wrote: > Hi! > > I have experience with subqs. > > Nori is really better today! She ate 2 dishes of wet food while i was > there. She is more active and attentive to what happens. > > Neurologist said Nori has a deficiency on the left side of the body, as if > she had a stroke. It can be because of anemia, an inflammation or even > malnutrition. > > Vet added a brain supplement (MCT's) to Nori's prescription. > > Fip isn't discarded but felv also justify this condition so I hope she has > nothing more. > > Vets said maybe Nori can come home tomorrow :) > > Thank you! > > Patr?cia > > > Em s?b, 8 de jun de 2019 ?s 23:23, Amani Oakley > escreveu: > >> One option is to ask your vet to show you how to give her subcutaneous >> fluids, which I do all the time for my cats if needed. However, for now, it >> makes sense to leave her there I guess. I presume they are warming the IV >> fluids too, because again, with such a small kitten, it wouldn?t take much >> to chill her if the fluids are at room temperature or colder. >> >> >> >> I guess it?s just me. I am pretty adamant about taking home my cats >> whenever possible, but I understand that Nori sounds like she needs some >> extra help. I just find that the cats respond far better to personal >> cuddling and love, and this makes them feel better, eat more, etc. >> >> >> >> Hopefully, she will feel better tomorrow. >> >> >> >> I?m crossing my fingers for you and Nori. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk * On Behalf Of *Patricia >> Oliveira >> *Sent:* June 8, 2019 9:53 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> She has fluids IV all the time and replenishment of potassium. Receives >> external heating too. >> >> >> >> They monitor pressure (low sometimes), oxygenation, temperature and heart >> rate several times a day. >> >> I wish she could come home soon but she has been dehydrated even with >> fluids IV. I don?t know if it is safe to bring her now. >> >> >> >> >> >> >> >> Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley >> escreveu: >> >> Patricia >> >> >> >> I agree with you that it is too early to tell, but for sure it is good >> news that the haematocrit is moving in the right direction. Very good news >> on the rosy gingiva. >> >> >> >> Rouleaux is likely only due to the transfusion. She appears to have had a >> bit of transfusion reaction, so the cells may be sticking to one another as >> a result. (Red cells in Rouleaux formation means that the look like a stack >> of coins ? one on top of the other. In humans, that presentation is >> consistent with multiple myeloma. I don?t think it means anything right now >> other than the new red cells may be reacting a bit with her own cells). >> >> >> >> I think she is working through the transfusion reaction, so that is >> likely why she is sleeping because you said that immediately after the >> transfusion, she was active and eating on her own. >> >> >> >> Low platelets are consistent with the FeLV presentation and the impact on >> the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that >> with my Zander, I had the red cell numbers recover first, before the >> platelets recovered. >> >> >> >> I presume they have her on a heating pad to keep her body temperature up. >> >> >> >> I suspect it might be premature to look at the neurology right now. She >> is working through a lot, and is a tiny kitten. She needs to be given time >> to recover from the transfusion reaction, and to allow the good food and >> medication to start to work. I don?t know how a neurological diagnosis >> could help you now, and one would expect the neurologist will have a >> difficult time seeing a true neurological deficit, with all the rest of the >> stuff happening. >> >> >> >> I would also suggest that at some point, it is better for her to be with >> you at home. If they are not giving her anything like fluids, you might >> consider taking her home with you. I know with Zander, he reacted most >> strongly when I was there with him. I could get him to play a little bit >> and that made him feel better, and of course, lots of cuddles and kisses. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* June 8, 2019 8:52 PM >> *To:* Sandra Wachtstetter ; >> felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Thank you, Sandra :) >> >> >> >> I visited Nori today. The hospital is in another city so I can't go there >> every day. >> >> >> >> She is a rosy gingiva, but continues to sleep most of the time and with a >> low temperature. One of the veterinarians there thinks that temperature is >> lower because of malnutrition, she has almost no lean mass and no fat. >> >> >> >> Nori will go through the evaluation of a neurologist tomorrow. Some >> hypotheses raised for this prostration are neurological, including a >> possible hypoxia before the first transfusion when her hematocrit was >> really low. >> >> >> >> Her blood work today is 30% hematocrit, the higher till now! So i think >> red cells aren?t being destroyed anymore, is it right or is it early to >> know? >> >> >> >> Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low >> platelets for the first time (92.000). >> >> >> >> Nori had an echocardiogram today too and it is ok. >> >> >> >> Thank you! >> >> >> >> Patr?cia >> >> >> >> Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter < >> swacht1946 at comcast.net> escreveu: >> >> Hello Patricia, you may already be doing this - but if not, please take a >> copy of Amani's conversations for the vet to read - may help. >> >> Good luck - don't give up!! >> >> Sandt W >> >> >> >> On June 7, 2019 at 9:55 PM Patricia Oliveira >> wrote: >> >> Nori did not want to eat by herself so they are syringing food. They >> started another medication for nausea, although she does not vomit, they >> think that may be why she does not eat. >> >> >> >> Blood work showed changes in neutrophils (bizarre core?), veternary says >> it can be from leukemia. >> >> >> >> The result of this transfusion was not as good as the other time :( >> >> >> >> i?ll talk to veterinary tomorrow morning again. >> >> >> >> thank you! >> >> >> >> Patr?cia >> >> >> >> >> >> >> >> Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com> >> escreveu: >> >> Still sounds more like a transfusion reaction than anything with the meds. >> >> >> >> Hang in there. See what the afternoon labs show. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* June 7, 2019 1:44 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Hi, Amani >> >> >> >> Nori is receiving doxy+prenisolone+stanazolol even in the hospital. >> >> >> >> I know it can be a reaction but i thought higher dose of prednisolone >> would prevent hemolysis. >> >> >> >> I also know it's normal for part of the red blood cells to be cleared >> right after the transfusion, but i don?t remember if it was icteric plasma >> on last one. >> >> >> >> I was hopefull she would come back home tomorrow, now i don?t know if it >> will be possible. >> >> >> >> Today she must have am echocardiogram too because x-ray showed an >> enlarged heart. >> >> >> >> Thank you! >> >> >> >> >> >> >> >> Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley >> escreveu: >> >> Hi Patricia >> >> >> >> The Stanozolol often has a side-effect of elevating liver enzymes, though >> I cannot remember if it also increased bilirubin (which would be what would >> cause the icteric observation of the plasma). However, hang in there. If it >> is the Stanozolol, my experience is that the liver enzymes drop right back >> to normal, shortly after it is discontinued, and there is no lasting damage >> to the liver. For now, what you have described (low temp and slightly lower >> heart rate) seems more likely to be related to the transfusion itself, >> rather than anything else going on. >> >> >> >> It is also possible that with the additional transfusion, there is a >> higher than normal red cell destruction going on, which would be another >> explanation for the increased icterus in the blood (which will also show as >> an increase in bilirubin). Elevated bilirubin can often be caused by a >> reaction to a blood transfusion. If the high bilirubin is the indirect or >> the unconjugated portion, it is related to red cell break down. The direct >> bilirubin (conjugated portion) is related to liver function. The lab >> results are usually broken down to Total bilirubin and Direct bilirubin. >> The indirect portion is obtained by subtracting the direct amount from the >> total amount. >> >> >> >> I myself went through the pressure of the vets wanting me to discontinue >> the Stanozolol because of abnormal liver enzymes. My logic was that there >> was nothing else. If I discontinued the Stanozolol, my cat would die, >> period. I continued and found that in the end, the liver enzymes normalized >> on their own, even though I had Zander on almost continuous Stanozolol for >> close to two years. >> >> >> >> I know that you know that you are only temporarily helping Nori with >> blood transfusions, and the virus is still attacking cells, etc. In my >> opinion ? and mine alone ? my experience and research leads me to the >> conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked >> to not only boost the red cell production, but I believe that the >> Doxycyline assisted in keeping the viruses from properly reproducing. >> >> >> >> However, anticipate that when the vet gets back the second set of blood >> work, she may well try to tell you to discontinue the Stanozolol. >> >> >> >> Amani >> >> >> >> >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* June 7, 2019 12:53 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Hi, Amani! >> >> >> >> Nori got another transfusion last night, hematocrit was 11.9 before it. >> >> >> >> Today morning, i talk to the hospital's veterinarian, she said hematocrit >> went to 29 and Nori was fine, all normal parameters and eating by herself >> again. >> >> >> >> But plasma was intensely icteric. I think this means red cells being >> destroyed, isn't it? >> >> >> >> About one hour ago, veterinarian said Nori was with low temperature and >> heart rate slightly lower than normal. She was waiting the new blood work. >> In the morning, it was done only hematocrit, not complete blood work. >> >> >> >> i am worried again. >> >> >> >> Thank you, >> >> >> >> Patr?cia >> >> >> >> Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley >> escreveu: >> >> I would be leery of the going the route suggested by the vet at this >> juncture. I seriously seriously doubt if the erythropoietin will help. See >> my earlier where I explain why. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* June 4, 2019 8:53 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Hi, Lorraine >> >> >> >> Veterinary wants to increase prednisolone to immunosuppressive dose and >> add erythropoietin. She thinks it is immune-mediated anemia and >> not mycoplasma. >> >> >> >> Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 >> kg. >> >> >> >> We did x-ray today too. No visible tumor but we found a >> possible cardiopathy ("Increased globular-looking heart silhouette"). >> >> >> >> :( >> >> >> >> >> >> >> >> Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < >> johnston1110 at comcast.net> escreveu: >> >> Patricia, >> >> >> >> I would go with the transfusion and also start erythropoietin. >> Stanozolol is supposed to stimulate erythropoietin production, but she >> might need a boost of the ready-made drug just to keep her alive until then. >> >> >> >> - Lorraine >> >> >> >> "Sometimes it is the people no one can imagine anything of who do the >> things no one can imagine." - Alan Turing >> >> >> >> *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On Behalf >> Of *Patricia Oliveira >> *Sent:* Tuesday, June 4, 2019 6:34 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Hi, >> >> >> >> We did another blood work today, her hematocrit is 13% now :( >> >> >> >> She is very sleepy but responsive when i talk to her. >> >> >> >> I don?t know if i can wait some more days to see if stanozolol is >> working. Or maybe it would be better get another transfusion right now. >> >> >> >> Today, vet talk about erythropoietin. Do you know if it can be used with >> stanozolol? >> >> >> >> Thank you, >> >> >> >> Patr?cia >> >> >> >> Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley >> escreveu: >> >> Hi Patricia ? I gave all the pills together, morning and evening, except >> for the metoclopramide which was given ? or so before meals. The rest I >> gave with the meals. I didn?t observe a problem with giving them together. >> >> >> >> You might also try baby food to get Nori to eat. Get the pureed kind >> (beef or chicken with or without vegetables), so it can be sucked up into a >> syringe. If my Zander wasn?t eating (and he wasn?t at the start of the >> medication regime), then I would use a syringe to get the baby food into >> him. Baby food is easy to digest and has good things in it. I would target >> ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number >> of syringe-fulls if possible. Eventually, Zander started eating the baby >> food on his own, and then I graduated to moist food, and really, anything >> he wanted until he put the weight back on. >> >> >> >> I had a look at the picture you sent and Nori is adorable. I am crossing >> my fingers for you and for Nori. Keep us updated on her progress. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* June 1, 2019 12:36 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Hi, Amani! >> >> >> >> Thanky you very much for you email! >> >> >> >> Nori was discharged from the hospital yesterday night. She is eating baby >> dry food. I tried canned but she didn?t accept so weel. >> >> >> >> Today i bought other kinds of canned, i'll try them hoping she likes some >> one. >> >> >> >> Compound pharmacy must delivery stanozolol today. >> >> >> >> Are there any precautions regarding medication schedules? Close or far to >> doxy, for example? >> >> >> >> This is Nori: >> https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html >> >> >> >> >> >> >> Thank you! >> >> >> >> Patr?cia >> >> >> >> Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley >> escreveu: >> >> Sorry Patricia ? after going on and on in my last email, I realized I >> hadn?t actually answered your question. I think you can probably use the >> stanozolol with the Doxycycline, without the prednisone, but prednisone >> itself has properties which help to boost red cell production. Try it out, >> keep close tabs on the haematology results and see if you are getting a >> good response on just Doxycycline and the Stanozolol. If not, add the >> prednisone. You may find that this combination assists with the FIP as >> well, as per my previous email. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* May 30, 2019 12:56 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* [Felvtalk] Rescued kitten felv + >> >> >> >> Hi from Brazil, >> >> >> >> I rescued a very weak, dehydrated, extremely thin kitten. >> >> >> She's hospitalized now. Her hematocrit was 8, had blood transfusion which >> raised hematocrit to 22, now it is 19. Low reticulocyte count. >> >> She has difficulty walking, which we can not define if it is just >> weakness or neurological. Already had a seizure. >> >> She also have changes in her kidneys. It has been tested and is felv + >> >> She is receiving doxy and the hospital vets would like to include >> prednisolone. >> >> However, as it is not possible yet to rule out PIF, and the medication I >> could use in the case of PIF does not work if the cat received >> prednisolone, I am trying to avoid it. >> >> The veterinarian agreed to prescribe stanozolol. >> >> Can it be used without prednisolone, only with doxy she is already >> receiving? >> >> Thank you! >> >> >> >> Patr?cia >> >> _______________________________________________ >> Felvtalk mailing list >> Felvtalk at felineleukemia.org >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org >> >> _______________________________________________ >> Felvtalk mailing list >> Felvtalk at felineleukemia.org >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org >> >> _______________________________________________ >> Felvtalk mailing list >> Felvtalk at felineleukemia.org >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org >> >> _______________________________________________ >> Felvtalk mailing list >> Felvtalk at felineleukemia.org >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org >> > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From emccarty44 at gmail.com Sun Jun 9 19:58:01 2019 From: emccarty44 at gmail.com (Liz Baumeister) Date: Sun, 9 Jun 2019 17:58:01 -0700 Subject: [Felvtalk] Felvtalk Digest, Vol 55, Issue 19 In-Reply-To: References: Message-ID: Hi please unsubscribe me from your mailing list On Sun, Jun 9, 2019, 5:08 PM wrote: > Send Felvtalk mailing list submissions to > felvtalk at felineleukemia.org > > To subscribe or unsubscribe via the World Wide Web, visit > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > or, via email, send a message with subject or body 'help' to > felvtalk-request at felineleukemia.org > > You can reach the person managing the list at > felvtalk-owner at felineleukemia.org > > When replying, please edit your Subject line so it is more specific > than "Re: Contents of Felvtalk digest..." > > > Today's Topics: > > 1. Re: Rescued kitten felv + (Lorraine Johnston) > 2. Re: Rescued kitten felv + (Pam Doore) > > > ---------------------------------------------------------------------- > > Message: 1 > Date: Sun, 9 Jun 2019 18:26:42 -0400 > From: "Lorraine Johnston" > To: > Subject: Re: [Felvtalk] Rescued kitten felv + > Message-ID: <002d01d51f12$703e6f70$50bb4e50$@net> > Content-Type: text/plain; charset="utf-8" > > Excellent news about Nori! > > > > - Lorraine > > > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > > > From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] On Behalf Of > Patricia Oliveira > Sent: Sunday, June 9, 2019 2:09 PM > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > Hi! > > > > I have experience with subqs. > > > > Nori is really better today! She ate 2 dishes of wet food while i was > there. She is more active and attentive to what happens. > > > > Neurologist said Nori has a deficiency on the left side of the body, as if > she had a stroke. It can be because of anemia, an inflammation or even > malnutrition. > > > > Vet added a brain supplement (MCT's) to Nori's prescription. > > > > Fip isn't discarded but felv also justify this condition so I hope she has > nothing more. > > > > Vets said maybe Nori can come home tomorrow :) > > > > Thank you! > > > > Patr?cia > > -------------- next part -------------- > An HTML attachment was scrubbed... > URL: < > http://felineleukemia.org/pipermail/felvtalk_felineleukemia.org/attachments/20190609/b2831748/attachment-0001.html > > > > ------------------------------ > > Message: 2 > Date: Sun, 9 Jun 2019 20:07:43 -0400 > From: Pam Doore > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > Message-ID: > < > CA+-nMssZXQAQ9RdnvYurLF3vsrtQj7Ub-jGYGjq-CXskQXamtA at mail.gmail.com> > Content-Type: text/plain; charset="utf-8" > > That is great news about Nori! > > ~~@~~~~~@~~~~~@~~~~~@~~~~~@~~~~ > > *Christ beside me, Christ before me, Christ behind me, Christ within me, > Christ beneath me, Christ above me. ? **St. Patrick* > > > > On Sun, Jun 9, 2019 at 2:10 PM Patricia Oliveira > wrote: > > > Hi! > > > > I have experience with subqs. > > > > Nori is really better today! She ate 2 dishes of wet food while i was > > there. She is more active and attentive to what happens. > > > > Neurologist said Nori has a deficiency on the left side of the body, as > if > > she had a stroke. It can be because of anemia, an inflammation or even > > malnutrition. > > > > Vet added a brain supplement (MCT's) to Nori's prescription. > > > > Fip isn't discarded but felv also justify this condition so I hope she > has > > nothing more. > > > > Vets said maybe Nori can come home tomorrow :) > > > > Thank you! > > > > Patr?cia > > > > > > Em s?b, 8 de jun de 2019 ?s 23:23, Amani Oakley > > > escreveu: > > > >> One option is to ask your vet to show you how to give her subcutaneous > >> fluids, which I do all the time for my cats if needed. However, for > now, it > >> makes sense to leave her there I guess. I presume they are warming the > IV > >> fluids too, because again, with such a small kitten, it wouldn?t take > much > >> to chill her if the fluids are at room temperature or colder. > >> > >> > >> > >> I guess it?s just me. I am pretty adamant about taking home my cats > >> whenever possible, but I understand that Nori sounds like she needs some > >> extra help. I just find that the cats respond far better to personal > >> cuddling and love, and this makes them feel better, eat more, etc. > >> > >> > >> > >> Hopefully, she will feel better tomorrow. > >> > >> > >> > >> I?m crossing my fingers for you and Nori. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk * On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 8, 2019 9:53 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> She has fluids IV all the time and replenishment of potassium. Receives > >> external heating too. > >> > >> > >> > >> They monitor pressure (low sometimes), oxygenation, temperature and > heart > >> rate several times a day. > >> > >> I wish she could come home soon but she has been dehydrated even with > >> fluids IV. I don?t know if it is safe to bring her now. > >> > >> > >> > >> > >> > >> > >> > >> Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> Patricia > >> > >> > >> > >> I agree with you that it is too early to tell, but for sure it is good > >> news that the haematocrit is moving in the right direction. Very good > news > >> on the rosy gingiva. > >> > >> > >> > >> Rouleaux is likely only due to the transfusion. She appears to have had > a > >> bit of transfusion reaction, so the cells may be sticking to one > another as > >> a result. (Red cells in Rouleaux formation means that the look like a > stack > >> of coins ? one on top of the other. In humans, that presentation is > >> consistent with multiple myeloma. I don?t think it means anything right > now > >> other than the new red cells may be reacting a bit with her own cells). > >> > >> > >> > >> I think she is working through the transfusion reaction, so that is > >> likely why she is sleeping because you said that immediately after the > >> transfusion, she was active and eating on her own. > >> > >> > >> > >> Low platelets are consistent with the FeLV presentation and the impact > on > >> the bone marrow. Hopefully, the Stanozolol will help. I seem to recall > that > >> with my Zander, I had the red cell numbers recover first, before the > >> platelets recovered. > >> > >> > >> > >> I presume they have her on a heating pad to keep her body temperature > up. > >> > >> > >> > >> I suspect it might be premature to look at the neurology right now. She > >> is working through a lot, and is a tiny kitten. She needs to be given > time > >> to recover from the transfusion reaction, and to allow the good food and > >> medication to start to work. I don?t know how a neurological diagnosis > >> could help you now, and one would expect the neurologist will have a > >> difficult time seeing a true neurological deficit, with all the rest of > the > >> stuff happening. > >> > >> > >> > >> I would also suggest that at some point, it is better for her to be with > >> you at home. If they are not giving her anything like fluids, you might > >> consider taking her home with you. I know with Zander, he reacted most > >> strongly when I was there with him. I could get him to play a little bit > >> and that made him feel better, and of course, lots of cuddles and > kisses. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 8, 2019 8:52 PM > >> *To:* Sandra Wachtstetter ; > >> felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Thank you, Sandra :) > >> > >> > >> > >> I visited Nori today. The hospital is in another city so I can't go > there > >> every day. > >> > >> > >> > >> She is a rosy gingiva, but continues to sleep most of the time and with > a > >> low temperature. One of the veterinarians there thinks that temperature > is > >> lower because of malnutrition, she has almost no lean mass and no fat. > >> > >> > >> > >> Nori will go through the evaluation of a neurologist tomorrow. Some > >> hypotheses raised for this prostration are neurological, including a > >> possible hypoxia before the first transfusion when her hematocrit was > >> really low. > >> > >> > >> > >> Her blood work today is 30% hematocrit, the higher till now! So i think > >> red cells aren?t being destroyed anymore, is it right or is it early to > >> know? > >> > >> > >> > >> Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low > >> platelets for the first time (92.000). > >> > >> > >> > >> Nori had an echocardiogram today too and it is ok. > >> > >> > >> > >> Thank you! > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter < > >> swacht1946 at comcast.net> escreveu: > >> > >> Hello Patricia, you may already be doing this - but if not, please take > a > >> copy of Amani's conversations for the vet to read - may help. > >> > >> Good luck - don't give up!! > >> > >> Sandt W > >> > >> > >> > >> On June 7, 2019 at 9:55 PM Patricia Oliveira > >> wrote: > >> > >> Nori did not want to eat by herself so they are syringing food. They > >> started another medication for nausea, although she does not vomit, they > >> think that may be why she does not eat. > >> > >> > >> > >> Blood work showed changes in neutrophils (bizarre core?), veternary says > >> it can be from leukemia. > >> > >> > >> > >> The result of this transfusion was not as good as the other time :( > >> > >> > >> > >> i?ll talk to veterinary tomorrow morning again. > >> > >> > >> > >> thank you! > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> > >> > >> > >> > >> Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> Still sounds more like a transfusion reaction than anything with the > meds. > >> > >> > >> > >> Hang in there. See what the afternoon labs show. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 7, 2019 1:44 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Amani > >> > >> > >> > >> Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > >> > >> > >> > >> I know it can be a reaction but i thought higher dose of prednisolone > >> would prevent hemolysis. > >> > >> > >> > >> I also know it's normal for part of the red blood cells to be cleared > >> right after the transfusion, but i don?t remember if it was icteric > plasma > >> on last one. > >> > >> > >> > >> I was hopefull she would come back home tomorrow, now i don?t know if it > >> will be possible. > >> > >> > >> > >> Today she must have am echocardiogram too because x-ray showed an > >> enlarged heart. > >> > >> > >> > >> Thank you! > >> > >> > >> > >> > >> > >> > >> > >> Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> Hi Patricia > >> > >> > >> > >> The Stanozolol often has a side-effect of elevating liver enzymes, > though > >> I cannot remember if it also increased bilirubin (which would be what > would > >> cause the icteric observation of the plasma). However, hang in there. > If it > >> is the Stanozolol, my experience is that the liver enzymes drop right > back > >> to normal, shortly after it is discontinued, and there is no lasting > damage > >> to the liver. For now, what you have described (low temp and slightly > lower > >> heart rate) seems more likely to be related to the transfusion itself, > >> rather than anything else going on. > >> > >> > >> > >> It is also possible that with the additional transfusion, there is a > >> higher than normal red cell destruction going on, which would be another > >> explanation for the increased icterus in the blood (which will also > show as > >> an increase in bilirubin). Elevated bilirubin can often be caused by a > >> reaction to a blood transfusion. If the high bilirubin is the indirect > or > >> the unconjugated portion, it is related to red cell break down. The > direct > >> bilirubin (conjugated portion) is related to liver function. The lab > >> results are usually broken down to Total bilirubin and Direct bilirubin. > >> The indirect portion is obtained by subtracting the direct amount from > the > >> total amount. > >> > >> > >> > >> I myself went through the pressure of the vets wanting me to discontinue > >> the Stanozolol because of abnormal liver enzymes. My logic was that > there > >> was nothing else. If I discontinued the Stanozolol, my cat would die, > >> period. I continued and found that in the end, the liver enzymes > normalized > >> on their own, even though I had Zander on almost continuous Stanozolol > for > >> close to two years. > >> > >> > >> > >> I know that you know that you are only temporarily helping Nori with > >> blood transfusions, and the virus is still attacking cells, etc. In my > >> opinion ? and mine alone ? my experience and research leads me to the > >> conclusion that the combination of Doxycycline/Prednisone/Stanozolol > worked > >> to not only boost the red cell production, but I believe that the > >> Doxycyline assisted in keeping the viruses from properly reproducing. > >> > >> > >> > >> However, anticipate that when the vet gets back the second set of blood > >> work, she may well try to tell you to discontinue the Stanozolol. > >> > >> > >> > >> Amani > >> > >> > >> > >> > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 7, 2019 12:53 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Amani! > >> > >> > >> > >> Nori got another transfusion last night, hematocrit was 11.9 before it. > >> > >> > >> > >> Today morning, i talk to the hospital's veterinarian, she said > hematocrit > >> went to 29 and Nori was fine, all normal parameters and eating by > herself > >> again. > >> > >> > >> > >> But plasma was intensely icteric. I think this means red cells being > >> destroyed, isn't it? > >> > >> > >> > >> About one hour ago, veterinarian said Nori was with low temperature and > >> heart rate slightly lower than normal. She was waiting the new blood > work. > >> In the morning, it was done only hematocrit, not complete blood work. > >> > >> > >> > >> i am worried again. > >> > >> > >> > >> Thank you, > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> I would be leery of the going the route suggested by the vet at this > >> juncture. I seriously seriously doubt if the erythropoietin will help. > See > >> my earlier where I explain why. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 4, 2019 8:53 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Lorraine > >> > >> > >> > >> Veterinary wants to increase prednisolone to immunosuppressive dose and > >> add erythropoietin. She thinks it is immune-mediated anemia and > >> not mycoplasma. > >> > >> > >> > >> Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 > >> kg. > >> > >> > >> > >> We did x-ray today too. No visible tumor but we found a > >> possible cardiopathy ("Increased globular-looking heart silhouette"). > >> > >> > >> > >> :( > >> > >> > >> > >> > >> > >> > >> > >> Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < > >> johnston1110 at comcast.net> escreveu: > >> > >> Patricia, > >> > >> > >> > >> I would go with the transfusion and also start erythropoietin. > >> Stanozolol is supposed to stimulate erythropoietin production, but she > >> might need a boost of the ready-made drug just to keep her alive until > then. > >> > >> > >> > >> - Lorraine > >> > >> > >> > >> "Sometimes it is the people no one can imagine anything of who do the > >> things no one can imagine." - Alan Turing > >> > >> > >> > >> *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On > Behalf > >> Of *Patricia Oliveira > >> *Sent:* Tuesday, June 4, 2019 6:34 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, > >> > >> > >> > >> We did another blood work today, her hematocrit is 13% now :( > >> > >> > >> > >> She is very sleepy but responsive when i talk to her. > >> > >> > >> > >> I don?t know if i can wait some more days to see if stanozolol is > >> working. Or maybe it would be better get another transfusion right now. > >> > >> > >> > >> Today, vet talk about erythropoietin. Do you know if it can be used with > >> stanozolol? > >> > >> > >> > >> Thank you, > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> Hi Patricia ? I gave all the pills together, morning and evening, except > >> for the metoclopramide which was given ? or so before meals. The rest I > >> gave with the meals. I didn?t observe a problem with giving them > together. > >> > >> > >> > >> You might also try baby food to get Nori to eat. Get the pureed kind > >> (beef or chicken with or without vegetables), so it can be sucked up > into a > >> syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > >> medication regime), then I would use a syringe to get the baby food into > >> him. Baby food is easy to digest and has good things in it. I would > target > >> ? say ? five 3 cc syringe-fulls at each feeding. I would boost the > number > >> of syringe-fulls if possible. Eventually, Zander started eating the baby > >> food on his own, and then I graduated to moist food, and really, > anything > >> he wanted until he put the weight back on. > >> > >> > >> > >> I had a look at the picture you sent and Nori is adorable. I am crossing > >> my fingers for you and for Nori. Keep us updated on her progress. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 1, 2019 12:36 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Amani! > >> > >> > >> > >> Thanky you very much for you email! > >> > >> > >> > >> Nori was discharged from the hospital yesterday night. She is eating > baby > >> dry food. I tried canned but she didn?t accept so weel. > >> > >> > >> > >> Today i bought other kinds of canned, i'll try them hoping she likes > some > >> one. > >> > >> > >> > >> Compound pharmacy must delivery stanozolol today. > >> > >> > >> > >> Are there any precautions regarding medication schedules? Close or far > to > >> doxy, for example? > >> > >> > >> > >> This is Nori: > >> https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > >> < > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html?fbclid=IwAR0cXMedtfi73B81pJI7QiYGwRTJf9VJp-JN7S_Tstb0ANeg0Hm4ObtFH_A > > > >> > >> > >> > >> > >> > >> Thank you! > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> Sorry Patricia ? after going on and on in my last email, I realized I > >> hadn?t actually answered your question. I think you can probably use the > >> stanozolol with the Doxycycline, without the prednisone, but prednisone > >> itself has properties which help to boost red cell production. Try it > out, > >> keep close tabs on the haematology results and see if you are getting a > >> good response on just Doxycycline and the Stanozolol. If not, add the > >> prednisone. You may find that this combination assists with the FIP as > >> well, as per my previous email. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* May 30, 2019 12:56 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi from Brazil, > >> > >> > >> > >> I rescued a very weak, dehydrated, extremely thin kitten. > >> > >> > >> She's hospitalized now. Her hematocrit was 8, had blood transfusion > which > >> raised hematocrit to 22, now it is 19. Low reticulocyte count. > >> > >> She has difficulty walking, which we can not define if it is just > >> weakness or neurological. Already had a seizure. > >> > >> She also have changes in her kidneys. It has been tested and is felv + > >> > >> She is receiving doxy and the hospital vets would like to include > >> prednisolone. > >> > >> However, as it is not possible yet to rule out PIF, and the medication I > >> could use in the case of PIF does not work if the cat received > >> prednisolone, I am trying to avoid it. > >> > >> The veterinarian agreed to prescribe stanozolol. > >> > >> Can it be used without prednisolone, only with doxy she is already > >> receiving? > >> > >> Thank you! > >> > >> > >> > >> Patr?cia > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > > _______________________________________________ > > Felvtalk mailing list > > Felvtalk at felineleukemia.org > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > -------------- next part -------------- > An HTML attachment was scrubbed... > URL: < > http://felineleukemia.org/pipermail/felvtalk_felineleukemia.org/attachments/20190609/cf8c8a30/attachment.html > > > > ------------------------------ > > Subject: Digest Footer > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > ------------------------------ > > End of Felvtalk Digest, Vol 55, Issue 19 > **************************************** > -------------- next part -------------- An HTML attachment was scrubbed... URL: From swacht1946 at comcast.net Sun Jun 9 20:33:11 2019 From: swacht1946 at comcast.net (Sandra Wachtstetter) Date: Sun, 9 Jun 2019 21:33:11 -0400 (EDT) Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> Message-ID: <323934897.346017.1560130392364@connect.xfinity.com> Awesome news!!! > On June 9, 2019 at 2:09 PM Patricia Oliveira wrote: > > Hi! > > I have experience with subqs. > > Nori is really better today! She ate 2 dishes of wet food while i was there. She is more active and attentive to what happens. > > Neurologist said Nori has a deficiency on the left side of the body, as if she had a stroke. It can be because of anemia, an inflammation or even malnutrition. > > Vet added a brain supplement (MCT's) to Nori's prescription. > > Fip isn't discarded but felv also justify this condition so I hope she has nothing more. > > Vets said maybe Nori can come home tomorrow :) > > Thank you! > > Patr?cia > > > Em s?b, 8 de jun de 2019 ?s 23:23, Amani Oakley < aoakley at oakleylegal.com mailto:aoakley at oakleylegal.com > escreveu: > > > > > > One option is to ask your vet to show you how to give her subcutaneous fluids, which I do all the time for my cats if needed. However, for now, it makes sense to leave her there I guess. I presume they are warming the IV fluids too, because again, with such a small kitten, it wouldn?t take much to chill her if the fluids are at room temperature or colder. > > > > > > > > I guess it?s just me. I am pretty adamant about taking home my cats whenever possible, but I understand that Nori sounds like she needs some extra help. I just find that the cats respond far better to personal cuddling and love, and this makes them feel better, eat more, etc. > > > > > > > > Hopefully, she will feel better tomorrow. > > > > > > > > I?m crossing my fingers for you and Nori. > > > > > > > > Amani > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > Sent: June 8, 2019 9:53 PM > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > She has fluids IV all the time and replenishment of potassium. Receives external heating too. > > > > > > > > They monitor pressure (low sometimes), oxygenation, temperature and heart rate several times a day. > > > > I wish she could come home soon but she has been dehydrated even with fluids IV. I don?t know if it is safe to bring her now. > > > > > > > > > > > > > > > > Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley escreveu: > > > > > > > > > > Patricia > > > > > > > > > > > > I agree with you that it is too early to tell, but for sure it is good news that the haematocrit is moving in the right direction. Very good news on the rosy gingiva. > > > > > > > > > > > > Rouleaux is likely only due to the transfusion. She appears to have had a bit of transfusion reaction, so the cells may be sticking to one another as a result. (Red cells in Rouleaux formation means that the look like a stack of coins ? one on top of the other. In humans, that presentation is consistent with multiple myeloma. I don?t think it means anything right now other than the new red cells may be reacting a bit with her own cells). > > > > > > > > > > > > I think she is working through the transfusion reaction, so that is likely why she is sleeping because you said that immediately after the transfusion, she was active and eating on her own. > > > > > > > > > > > > Low platelets are consistent with the FeLV presentation and the impact on the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that with my Zander, I had the red cell numbers recover first, before the platelets recovered. > > > > > > > > > > > > I presume they have her on a heating pad to keep her body temperature up. > > > > > > > > > > > > I suspect it might be premature to look at the neurology right now. She is working through a lot, and is a tiny kitten. She needs to be given time to recover from the transfusion reaction, and to allow the good food and medication to start to work. I don?t know how a neurological diagnosis could help you now, and one would expect the neurologist will have a difficult time seeing a true neurological deficit, with all the rest of the stuff happening. > > > > > > > > > > > > I would also suggest that at some point, it is better for her to be with you at home. If they are not giving her anything like fluids, you might consider taking her home with you. I know with Zander, he reacted most strongly when I was there with him. I could get him to play a little bit and that made him feel better, and of course, lots of cuddles and kisses. > > > > > > > > > > > > Amani > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > Sent: June 8, 2019 8:52 PM > > > To: Sandra Wachtstetter ; felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > Thank you, Sandra :) > > > > > > > > > > > > I visited Nori today. The hospital is in another city so I can't go there every day. > > > > > > > > > > > > She is a rosy gingiva, but continues to sleep most of the time and with a low temperature. One of the veterinarians there thinks that temperature is lower because of malnutrition, she has almost no lean mass and no fat. > > > > > > > > > > > > Nori will go through the evaluation of a neurologist tomorrow. Some hypotheses raised for this prostration are neurological, including a possible hypoxia before the first transfusion when her hematocrit was really low. > > > > > > > > > > > > Her blood work today is 30% hematocrit, the higher till now! So i think red cells aren?t being destroyed anymore, is it right or is it early to know? > > > > > > > > > > > > Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low platelets for the first time (92.000). > > > > > > > > > > > > Nori had an echocardiogram today too and it is ok. > > > > > > > > > > > > Thank you! > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter escreveu: > > > > > > > > > > > > > > Hello Patricia, you may already be doing this - but if not, please take a copy of Amani's conversations for the vet to read - may help. > > > > > > > > Good luck - don't give up!! > > > > > > > > Sandt W > > > > > > > > > > > > > > > > > > > > > > > > > > On June 7, 2019 at 9:55 PM Patricia Oliveira wrote: > > > > > > > > > > Nori did not want to eat by herself so they are syringing food. They started another medication for nausea, although she does not vomit, they think that may be why she does not eat. > > > > > > > > > > > > > > > > > > > > Blood work showed changes in neutrophils (bizarre core?), veternary says it can be from leukemia. > > > > > > > > > > > > > > > > > > > > The result of this transfusion was not as good as the other time :( > > > > > > > > > > > > > > > > > > > > i?ll talk to veterinary tomorrow morning again. > > > > > > > > > > > > > > > > > > > > thank you! > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com mailto:aoakley at oakleylegal.com > escreveu: > > > > > > > > > > > > > > > > > > > > > > Still sounds more like a transfusion reaction than anything with the meds. > > > > > > > > > > > > > > > > > > > > > > > > Hang in there. See what the afternoon labs show. > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > Sent: June 7, 2019 1:44 PM > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > Hi, Amani > > > > > > > > > > > > > > > > > > > > > > > > Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > > > > > > > > > > > > > > > > > > > > > > > > I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. > > > > > > > > > > > > > > > > > > > > > > > > I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don?t remember if it was icteric plasma on last one. > > > > > > > > > > > > > > > > > > > > > > > > I was hopefull she would come back home tomorrow, now i don?t know if it will be possible. > > > > > > > > > > > > > > > > > > > > > > > > Today she must have am echocardiogram too because x-ray showed an enlarged heart. > > > > > > > > > > > > > > > > > > > > > > > > Thank you! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > Hi Patricia > > > > > > > > > > > > > > > > > > > > > > > > > > > > The Stanozolol often has a side-effect of elevating liver enzymes, though I cannot remember if it also increased bilirubin (which would be what would cause the icteric observation of the plasma). However, hang in there. If it is the Stanozolol, my experience is that the liver enzymes drop right back to normal, shortly after it is discontinued, and there is no lasting damage to the liver. For now, what you have described (low temp and slightly lower heart rate) seems more likely to be related to the transfusion itself, rather than anything else going on. > > > > > > > > > > > > > > > > > > > > > > > > > > > > It is also possible that with the additional transfusion, there is a higher than normal red cell destruction going on, which would be another explanation for the increased icterus in the blood (which will also show as an increase in bilirubin). Elevated bilirubin can often be caused by a reaction to a blood transfusion. If the high bilirubin is the indirect or the unconjugated portion, it is related to red cell break down. The direct bilirubin (conjugated portion) is related to liver function. The lab results are usually broken down to Total bilirubin and Direct bilirubin. The indirect portion is obtained by subtracting the direct amount from the total amount. > > > > > > > > > > > > > > > > > > > > > > > > > > > > I myself went through the pressure of the vets wanting me to discontinue the Stanozolol because of abnormal liver enzymes. My logic was that there was nothing else. If I discontinued the Stanozolol, my cat would die, period. I continued and found that in the end, the liver enzymes normalized on their own, even though I had Zander on almost continuous Stanozolol for close to two years. > > > > > > > > > > > > > > > > > > > > > > > > > > > > I know that you know that you are only temporarily helping Nori with blood transfusions, and the virus is still attacking cells, etc. In my opinion ? and mine alone ? my experience and research leads me to the conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell production, but I believe that the Doxycyline assisted in keeping the viruses from properly reproducing. > > > > > > > > > > > > > > > > > > > > > > > > > > > > However, anticipate that when the vet gets back the second set of blood work, she may well try to tell you to discontinue the Stanozolol. > > > > > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > > Sent: June 7, 2019 12:53 PM > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi, Amani! > > > > > > > > > > > > > > > > > > > > > > > > > > > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > > > > > > > > > > > > > > > > > > > > > > > > > > > Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. > > > > > > > > > > > > > > > > > > > > > > > > > > > > But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? > > > > > > > > > > > > > > > > > > > > > > > > > > > > About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. > > > > > > > > > > > > > > > > > > > > > > > > > > > > i am worried again. > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thank you, > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > > > Sent: June 4, 2019 8:53 PM > > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi, Lorraine > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > :( > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patricia, > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > - Lorraine > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org mailto:felvtalk-bounces at felineleukemia.org ] On Behalf Of Patricia Oliveira > > > > > > > > > Sent: Tuesday, June 4, 2019 6:34 PM > > > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi, > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > We did another blood work today, her hematocrit is 13% now :( > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > She is very sleepy but responsive when i talk to her. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thank you, > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > > > > > Sent: June 1, 2019 12:36 PM > > > > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi, Amani! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thanky you very much for you email! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Today i bought other kinds of canned, i'll try them hoping she likes some one. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Compound pharmacy must delivery stanozolol today. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Are there any precautions regarding medication schedules? Close or far to doxy, for example? > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html?fbclid=IwAR0cXMedtfi73B81pJI7QiYGwRTJf9VJp-JN7S_Tstb0ANeg0Hm4ObtFH_A > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thank you! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > > > > > > Sent: May 30, 2019 12:56 PM > > > > > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > > > > > Subject: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi from Brazil, > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. > > > > > > > > > > > > > > > > > > > > > > She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. > > > > > > > > > > > > > > > > > > > > > > She also have changes in her kidneys. It has been tested and is felv + > > > > > > > > > > > > > > > > > > > > > > She is receiving doxy and the hospital vets would like to include prednisolone. > > > > > > > > > > > > > > > > > > > > > > However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. > > > > > > > > > > > > > > > > > > > > > > The veterinarian agreed to prescribe stanozolol. > > > > > > > > > > > > > > > > > > > > > > Can it be used without prednisolone, only with doxy she is already receiving? > > > > > > > > > > > > > > > > > > > > > > Thank you! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > _______________________________________________ > > > > > Felvtalk mailing list > > > > > Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > > > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > > > > > > > > > > > > > > _______________________________________________ > > > > Felvtalk mailing list > > > > Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > > > > > > > > > > _______________________________________________ > > > Felvtalk mailing list > > > Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > > > > _______________________________________________ > > Felvtalk mailing list > > Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Sun Jun 9 21:49:10 2019 From: johnston1110 at comcast.net (LORRAINE JOHNSTON) Date: Sun, 9 Jun 2019 22:49:10 -0400 (EDT) Subject: [Felvtalk] Nori - neuro symptoms Message-ID: <1746929692.656149.1560134951598@connect.xfinity.com> Hi, Patricia, Just a thought to mention to the neurologist: if Nori is having neurologic symptoms, perhaps a test for toxoplasmosis would be wise. And you might also want to mention to the treating vets that opiates allow some drugs that would not otherwise cross the blood/brain barrier to do so. Thus if her neurologic symptoms are the result of some infection, giving her an opiate such as buprenorphine along with an antibiotic could help the drug reach brain tissue it might not otherwise reach. Best regards, Lorraine -------------- next part -------------- An HTML attachment was scrubbed... URL: From bchapel at optonline.net Mon Jun 10 11:20:01 2019 From: bchapel at optonline.net (ROBERT CHAPEL) Date: Mon, 10 Jun 2019 12:20:01 -0400 (EDT) Subject: [Felvtalk] Nori's News In-Reply-To: References: Message-ID: <214885647.2479.1560183601278@mymail.optimum.net> Patricia... I'm so happy that you have some _ good_ news for once... You are very special to care so lovingly for this unfortunate kitten and if she makes it there will be NO question she has you to thank... Bob in Warwick NY > On June 9, 2019 at 9:33 PM felvtalk-request at felineleukemia.org wrote: > > > Send Felvtalk mailing list submissions to > felvtalk at felineleukemia.org > > To subscribe or unsubscribe via the World Wide Web, visit > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > or, via email, send a message with subject or body 'help' to > felvtalk-request at felineleukemia.org > > You can reach the person managing the list at > felvtalk-owner at felineleukemia.org > > When replying, please edit your Subject line so it is more specific > than "Re: Contents of Felvtalk digest..." > > > Today's Topics: > > 1. Re: Rescued kitten felv + (Sandra Wachtstetter) > > > ---------------------------------------------------------------------- > > Message: 1 > Date: Sun, 9 Jun 2019 21:33:11 -0400 (EDT) > From: Sandra Wachtstetter > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > Message-ID: <323934897.346017.1560130392364 at connect.xfinity.com> > Content-Type: text/plain; charset="utf-8" > > Awesome news!!! > > > > On June 9, 2019 at 2:09 PM Patricia Oliveira wrote: > > > > Hi! > > > > I have experience with subqs. > > > > Nori is really better today! She ate 2 dishes of wet food while i was there. She is more active and attentive to what happens. > > > > Neurologist said Nori has a deficiency on the left side of the body, as if she had a stroke. It can be because of anemia, an inflammation or even malnutrition. > > > > Vet added a brain supplement (MCT's) to Nori's prescription. > > > > Fip isn't discarded but felv also justify this condition so I hope she has nothing more. > > > > Vets said maybe Nori can come home tomorrow :) > > > > Thank you! > > > > Patr?cia > > > > > > Em s?b, 8 de jun de 2019 ?s 23:23, Amani Oakley < aoakley at oakleylegal.com mailto:aoakley at oakleylegal.com > escreveu: > > > > > > > > > One option is to ask your vet to show you how to give her subcutaneous fluids, which I do all the time for my cats if needed. However, for now, it makes sense to leave her there I guess. I presume they are warming the IV fluids too, because again, with such a small kitten, it wouldn?t take much to chill her if the fluids are at room temperature or colder. > > > > > > > > > > > > I guess it?s just me. I am pretty adamant about taking home my cats whenever possible, but I understand that Nori sounds like she needs some extra help. I just find that the cats respond far better to personal cuddling and love, and this makes them feel better, eat more, etc. > > > > > > > > > > > > Hopefully, she will feel better tomorrow. > > > > > > > > > > > > I?m crossing my fingers for you and Nori. > > > > > > > > > > > > Amani > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > Sent: June 8, 2019 9:53 PM > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > She has fluids IV all the time and replenishment of potassium. Receives external heating too. > > > > > > > > > > > > They monitor pressure (low sometimes), oxygenation, temperature and heart rate several times a day. > > > > > > I wish she could come home soon but she has been dehydrated even with fluids IV. I don?t know if it is safe to bring her now. > > > > > > > > > > > > > > > > > > > > > > > > Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley escreveu: > > > > > > > > > > > > > Patricia > > > > > > > > > > > > > > > > I agree with you that it is too early to tell, but for sure it is good news that the haematocrit is moving in the right direction. Very good news on the rosy gingiva. > > > > > > > > > > > > > > > > Rouleaux is likely only due to the transfusion. She appears to have had a bit of transfusion reaction, so the cells may be sticking to one another as a result. (Red cells in Rouleaux formation means that the look like a stack of coins ? one on top of the other. In humans, that presentation is consistent with multiple myeloma. I don?t think it means anything right now other than the new red cells may be reacting a bit with her own cells). > > > > > > > > > > > > > > > > I think she is working through the transfusion reaction, so that is likely why she is sleeping because you said that immediately after the transfusion, she was active and eating on her own. > > > > > > > > > > > > > > > > Low platelets are consistent with the FeLV presentation and the impact on the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that with my Zander, I had the red cell numbers recover first, before the platelets recovered. > > > > > > > > > > > > > > > > I presume they have her on a heating pad to keep her body temperature up. > > > > > > > > > > > > > > > > I suspect it might be premature to look at the neurology right now. She is working through a lot, and is a tiny kitten. She needs to be given time to recover from the transfusion reaction, and to allow the good food and medication to start to work. I don?t know how a neurological diagnosis could help you now, and one would expect the neurologist will have a difficult time seeing a true neurological deficit, with all the rest of the stuff happening. > > > > > > > > > > > > > > > > I would also suggest that at some point, it is better for her to be with you at home. If they are not giving her anything like fluids, you might consider taking her home with you. I know with Zander, he reacted most strongly when I was there with him. I could get him to play a little bit and that made him feel better, and of course, lots of cuddles and kisses. > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > Sent: June 8, 2019 8:52 PM > > > > To: Sandra Wachtstetter ; felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > Thank you, Sandra :) > > > > > > > > > > > > > > > > I visited Nori today. The hospital is in another city so I can't go there every day. > > > > > > > > > > > > > > > > She is a rosy gingiva, but continues to sleep most of the time and with a low temperature. One of the veterinarians there thinks that temperature is lower because of malnutrition, she has almost no lean mass and no fat. > > > > > > > > > > > > > > > > Nori will go through the evaluation of a neurologist tomorrow. Some hypotheses raised for this prostration are neurological, including a possible hypoxia before the first transfusion when her hematocrit was really low. > > > > > > > > > > > > > > > > Her blood work today is 30% hematocrit, the higher till now! So i think red cells aren?t being destroyed anymore, is it right or is it early to know? > > > > > > > > > > > > > > > > Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low platelets for the first time (92.000). > > > > > > > > > > > > > > > > Nori had an echocardiogram today too and it is ok. > > > > > > > > > > > > > > > > Thank you! > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter escreveu: > > > > > > > > > > > > > > > > > Hello Patricia, you may already be doing this - but if not, please take a copy of Amani's conversations for the vet to read - may help. > > > > > > > > > > Good luck - don't give up!! > > > > > > > > > > Sandt W > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > On June 7, 2019 at 9:55 PM Patricia Oliveira wrote: > > > > > > > > > > > > Nori did not want to eat by herself so they are syringing food. They started another medication for nausea, although she does not vomit, they think that may be why she does not eat. > > > > > > > > > > > > > > > > > > > > > > > > Blood work showed changes in neutrophils (bizarre core?), veternary says it can be from leukemia. > > > > > > > > > > > > > > > > > > > > > > > > The result of this transfusion was not as good as the other time :( > > > > > > > > > > > > > > > > > > > > > > > > i?ll talk to veterinary tomorrow morning again. > > > > > > > > > > > > > > > > > > > > > > > > thank you! > > > > > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com mailto:aoakley at oakleylegal.com > escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > Still sounds more like a transfusion reaction than anything with the meds. > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hang in there. See what the afternoon labs show. > > > > > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > > Sent: June 7, 2019 1:44 PM > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi, Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > > > > > > > > > > > > > > > > > > > > > > > > > > > > I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. > > > > > > > > > > > > > > > > > > > > > > > > > > > > I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don?t remember if it was icteric plasma on last one. > > > > > > > > > > > > > > > > > > > > > > > > > > > > I was hopefull she would come back home tomorrow, now i don?t know if it will be possible. > > > > > > > > > > > > > > > > > > > > > > > > > > > > Today she must have am echocardiogram too because x-ray showed an enlarged heart. > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thank you! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi Patricia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > The Stanozolol often has a side-effect of elevating liver enzymes, though I cannot remember if it also increased bilirubin (which would be what would cause the icteric observation of the plasma). However, hang in there. If it is the Stanozolol, my experience is that the liver enzymes drop right back to normal, shortly after it is discontinued, and there is no lasting damage to the liver. For now, what you have described (low temp and slightly lower heart rate) seems more likely to be related to the transfusion itself, rather than anything else going on. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > It is also possible that with the additional transfusion, there is a higher than normal red cell destruction going on, which would be another explanation for the increased icterus in the blood (which will also show as an increase in bilirubin). Elevated bilirubin can often be caused by a reaction to a blood transfusion. If the high bilirubin is the indirect or the unconjugated portion, it is related to red cell break down. The direct bilirubin (conjugated portion) is related to liver function. The lab results are usually broken down to Total bilirubin and Direct bilirubin. The indirect portion is obtained by subtracting the direct amount from the total amount. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I myself went through the pressure of the vets wanting me to discontinue the Stanozolol because of abnormal liver enzymes. My logic was that there was nothing else. If I discontinued the Stanozolol, my cat would die, period. I continued and found that in the end, the liver enzymes normalized on their own, even though I had Zander on almost continuous Stanozolol for close to two years. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I know that you know that you are only temporarily helping Nori with blood transfusions, and the virus is still attacking cells, etc. In my opinion ? and mine alone ? my experience and research leads me to the conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell production, but I believe that the Doxycyline assisted in keeping the viruses from properly reproducing. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > However, anticipate that when the vet gets back the second set of blood work, she may well try to tell you to discontinue the Stanozolol. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > > > Sent: June 7, 2019 12:53 PM > > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi, Amani! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > i am worried again. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thank you, > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > > > > Sent: June 4, 2019 8:53 PM > > > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi, Lorraine > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > :( > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patricia, > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > - Lorraine > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org mailto:felvtalk-bounces at felineleukemia.org ] On Behalf Of Patricia Oliveira > > > > > > > > > > Sent: Tuesday, June 4, 2019 6:34 PM > > > > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi, > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > We did another blood work today, her hematocrit is 13% now :( > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > She is very sleepy but responsive when i talk to her. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thank you, > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > > > > > > Sent: June 1, 2019 12:36 PM > > > > > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > > > > > Subject: Re: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi, Amani! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thanky you very much for you email! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Today i bought other kinds of canned, i'll try them hoping she likes some one. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Compound pharmacy must delivery stanozolol today. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Are there any precautions regarding medication schedules? Close or far to doxy, for example? > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html?fbclid=IwAR0cXMedtfi73B81pJI7QiYGwRTJf9VJp-JN7S_Tstb0ANeg0Hm4ObtFH_A > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Thank you! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley escreveu: > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Amani > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > From: Felvtalk On Behalf Of Patricia Oliveira > > > > > > > > > > > > Sent: May 30, 2019 12:56 PM > > > > > > > > > > > > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > > > > > > > > > > > Subject: [Felvtalk] Rescued kitten felv + > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Hi from Brazil, > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. > > > > > > > > > > > > > > > > > > > > > > > > She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. > > > > > > > > > > > > > > > > > > > > > > > > She also have changes in her kidneys. It has been tested and is felv + > > > > > > > > > > > > > > > > > > > > > > > > She is receiving doxy and the hospital vets would like to include prednisolone. > > > > > > > > > > > > > > > > > > > > > > > > However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. > > > > > > > > > > > > > > > > > > > > > > > > The veterinarian agreed to prescribe stanozolol. > > > > > > > > > > > > > > > > > > > > > > > > Can it be used without prednisolone, only with doxy she is already receiving? > > > > > > > > > > > > > > > > > > > > > > > > Thank you! > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Patr?cia > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > _______________________________________________ > > > > > > Felvtalk mailing list > > > > > > Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > > > > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > > > > > > > > > > > > > > > > > _______________________________________________ > > > > > Felvtalk mailing list > > > > > Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > > > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > > > > > > > > > > > > > _______________________________________________ > > > > Felvtalk mailing list > > > > Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > > > > > > _______________________________________________ > > > Felvtalk mailing list > > > Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > > > _______________________________________________ > > Felvtalk mailing list > > Felvtalk at felineleukemia.org > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > -------------- next part -------------- > An HTML attachment was scrubbed... > URL: > > ------------------------------ > > Subject: Digest Footer > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > ------------------------------ > > End of Felvtalk Digest, Vol 55, Issue 21 > **************************************** From ardyr at centurytel.net Mon Jun 10 22:20:48 2019 From: ardyr at centurytel.net (Ardy Robertson) Date: Mon, 10 Jun 2019 22:20:48 -0500 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> Message-ID: <000701d52004$aaf998e0$00eccaa0$@centurytel.net> Hello all ? I?m following Nori?s progress and please know, I?m keeping her in my thoughts and prayers too, hoping the Stanizolol/Doxy/Prednisolone combo works for her. She has chosen her owners well, thank you for taking such good care of her. And thanks Amani for the good advice as always. Ardy From: Felvtalk On Behalf Of Amani Oakley Sent: Saturday, June 8, 2019 9:23 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + One option is to ask your vet to show you how to give her subcutaneous fluids, which I do all the time for my cats if needed. However, for now, it makes sense to leave her there I guess. I presume they are warming the IV fluids too, because again, with such a small kitten, it wouldn?t take much to chill her if the fluids are at room temperature or colder. I guess it?s just me. I am pretty adamant about taking home my cats whenever possible, but I understand that Nori sounds like she needs some extra help. I just find that the cats respond far better to personal cuddling and love, and this makes them feel better, eat more, etc. Hopefully, she will feel better tomorrow. I?m crossing my fingers for you and Nori. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 8, 2019 9:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + She has fluids IV all the time and replenishment of potassium. Receives external heating too. They monitor pressure (low sometimes), oxygenation, temperature and heart rate several times a day. I wish she could come home soon but she has been dehydrated even with fluids IV. I don?t know if it is safe to bring her now. Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley > escreveu: Patricia I agree with you that it is too early to tell, but for sure it is good news that the haematocrit is moving in the right direction. Very good news on the rosy gingiva. Rouleaux is likely only due to the transfusion. She appears to have had a bit of transfusion reaction, so the cells may be sticking to one another as a result. (Red cells in Rouleaux formation means that the look like a stack of coins ? one on top of the other. In humans, that presentation is consistent with multiple myeloma. I don?t think it means anything right now other than the new red cells may be reacting a bit with her own cells). I think she is working through the transfusion reaction, so that is likely why she is sleeping because you said that immediately after the transfusion, she was active and eating on her own. Low platelets are consistent with the FeLV presentation and the impact on the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that with my Zander, I had the red cell numbers recover first, before the platelets recovered. I presume they have her on a heating pad to keep her body temperature up. I suspect it might be premature to look at the neurology right now. She is working through a lot, and is a tiny kitten. She needs to be given time to recover from the transfusion reaction, and to allow the good food and medication to start to work. I don?t know how a neurological diagnosis could help you now, and one would expect the neurologist will have a difficult time seeing a true neurological deficit, with all the rest of the stuff happening. I would also suggest that at some point, it is better for her to be with you at home. If they are not giving her anything like fluids, you might consider taking her home with you. I know with Zander, he reacted most strongly when I was there with him. I could get him to play a little bit and that made him feel better, and of course, lots of cuddles and kisses. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 8, 2019 8:52 PM To: Sandra Wachtstetter >; felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Thank you, Sandra :) I visited Nori today. The hospital is in another city so I can't go there every day. She is a rosy gingiva, but continues to sleep most of the time and with a low temperature. One of the veterinarians there thinks that temperature is lower because of malnutrition, she has almost no lean mass and no fat. Nori will go through the evaluation of a neurologist tomorrow. Some hypotheses raised for this prostration are neurological, including a possible hypoxia before the first transfusion when her hematocrit was really low. Her blood work today is 30% hematocrit, the higher till now! So i think red cells aren?t being destroyed anymore, is it right or is it early to know? Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low platelets for the first time (92.000). Nori had an echocardiogram today too and it is ok. Thank you! Patr?cia Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter > escreveu: Hello Patricia, you may already be doing this - but if not, please take a copy of Amani's conversations for the vet to read - may help. Good luck - don't give up!! Sandt W On June 7, 2019 at 9:55 PM Patricia Oliveira > wrote: Nori did not want to eat by herself so they are syringing food. They started another medication for nausea, although she does not vomit, they think that may be why she does not eat. Blood work showed changes in neutrophils (bizarre core?), veternary says it can be from leukemia. The result of this transfusion was not as good as the other time :( i?ll talk to veterinary tomorrow morning again. thank you! Patr?cia Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com > escreveu: Still sounds more like a transfusion reaction than anything with the meds. Hang in there. See what the afternoon labs show. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 1:44 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani Nori is receiving doxy+prenisolone+stanazolol even in the hospital. I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don?t remember if it was icteric plasma on last one. I was hopefull she would come back home tomorrow, now i don?t know if it will be possible. Today she must have am echocardiogram too because x-ray showed an enlarged heart. Thank you! Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: Hi Patricia The Stanozolol often has a side-effect of elevating liver enzymes, though I cannot remember if it also increased bilirubin (which would be what would cause the icteric observation of the plasma). However, hang in there. If it is the Stanozolol, my experience is that the liver enzymes drop right back to normal, shortly after it is discontinued, and there is no lasting damage to the liver. For now, what you have described (low temp and slightly lower heart rate) seems more likely to be related to the transfusion itself, rather than anything else going on. It is also possible that with the additional transfusion, there is a higher than normal red cell destruction going on, which would be another explanation for the increased icterus in the blood (which will also show as an increase in bilirubin). Elevated bilirubin can often be caused by a reaction to a blood transfusion. If the high bilirubin is the indirect or the unconjugated portion, it is related to red cell break down. The direct bilirubin (conjugated portion) is related to liver function. The lab results are usually broken down to Total bilirubin and Direct bilirubin. The indirect portion is obtained by subtracting the direct amount from the total amount. I myself went through the pressure of the vets wanting me to discontinue the Stanozolol because of abnormal liver enzymes. My logic was that there was nothing else. If I discontinued the Stanozolol, my cat would die, period. I continued and found that in the end, the liver enzymes normalized on their own, even though I had Zander on almost continuous Stanozolol for close to two years. I know that you know that you are only temporarily helping Nori with blood transfusions, and the virus is still attacking cells, etc. In my opinion ? and mine alone ? my experience and research leads me to the conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell production, but I believe that the Doxycyline assisted in keeping the viruses from properly reproducing. However, anticipate that when the vet gets back the second set of blood work, she may well try to tell you to discontinue the Stanozolol. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 12:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Nori got another transfusion last night, hematocrit was 11.9 before it. Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. i am worried again. Thank you, Patr?cia Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 4, 2019 8:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Lorraine Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). :( Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston escreveu: Patricia, I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org ] On Behalf Of Patricia Oliveira Sent: Tuesday, June 4, 2019 6:34 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From aoakley at oakleylegal.com Mon Jun 10 22:22:36 2019 From: aoakley at oakleylegal.com (Amani Oakley) Date: Tue, 11 Jun 2019 03:22:36 +0000 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: <000701d52004$aaf998e0$00eccaa0$@centurytel.net> References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> <000701d52004$aaf998e0$00eccaa0$@centurytel.net> Message-ID: We?re all pulling for Nori. Amani From: Felvtalk On Behalf Of Ardy Robertson Sent: June 10, 2019 11:21 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hello all ? I?m following Nori?s progress and please know, I?m keeping her in my thoughts and prayers too, hoping the Stanizolol/Doxy/Prednisolone combo works for her. She has chosen her owners well, thank you for taking such good care of her. And thanks Amani for the good advice as always. Ardy From: Felvtalk > On Behalf Of Amani Oakley Sent: Saturday, June 8, 2019 9:23 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + One option is to ask your vet to show you how to give her subcutaneous fluids, which I do all the time for my cats if needed. However, for now, it makes sense to leave her there I guess. I presume they are warming the IV fluids too, because again, with such a small kitten, it wouldn?t take much to chill her if the fluids are at room temperature or colder. I guess it?s just me. I am pretty adamant about taking home my cats whenever possible, but I understand that Nori sounds like she needs some extra help. I just find that the cats respond far better to personal cuddling and love, and this makes them feel better, eat more, etc. Hopefully, she will feel better tomorrow. I?m crossing my fingers for you and Nori. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 8, 2019 9:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + She has fluids IV all the time and replenishment of potassium. Receives external heating too. They monitor pressure (low sometimes), oxygenation, temperature and heart rate several times a day. I wish she could come home soon but she has been dehydrated even with fluids IV. I don?t know if it is safe to bring her now. Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley > escreveu: Patricia I agree with you that it is too early to tell, but for sure it is good news that the haematocrit is moving in the right direction. Very good news on the rosy gingiva. Rouleaux is likely only due to the transfusion. She appears to have had a bit of transfusion reaction, so the cells may be sticking to one another as a result. (Red cells in Rouleaux formation means that the look like a stack of coins ? one on top of the other. In humans, that presentation is consistent with multiple myeloma. I don?t think it means anything right now other than the new red cells may be reacting a bit with her own cells). I think she is working through the transfusion reaction, so that is likely why she is sleeping because you said that immediately after the transfusion, she was active and eating on her own. Low platelets are consistent with the FeLV presentation and the impact on the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that with my Zander, I had the red cell numbers recover first, before the platelets recovered. I presume they have her on a heating pad to keep her body temperature up. I suspect it might be premature to look at the neurology right now. She is working through a lot, and is a tiny kitten. She needs to be given time to recover from the transfusion reaction, and to allow the good food and medication to start to work. I don?t know how a neurological diagnosis could help you now, and one would expect the neurologist will have a difficult time seeing a true neurological deficit, with all the rest of the stuff happening. I would also suggest that at some point, it is better for her to be with you at home. If they are not giving her anything like fluids, you might consider taking her home with you. I know with Zander, he reacted most strongly when I was there with him. I could get him to play a little bit and that made him feel better, and of course, lots of cuddles and kisses. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 8, 2019 8:52 PM To: Sandra Wachtstetter >; felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Thank you, Sandra :) I visited Nori today. The hospital is in another city so I can't go there every day. She is a rosy gingiva, but continues to sleep most of the time and with a low temperature. One of the veterinarians there thinks that temperature is lower because of malnutrition, she has almost no lean mass and no fat. Nori will go through the evaluation of a neurologist tomorrow. Some hypotheses raised for this prostration are neurological, including a possible hypoxia before the first transfusion when her hematocrit was really low. Her blood work today is 30% hematocrit, the higher till now! So i think red cells aren?t being destroyed anymore, is it right or is it early to know? Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low platelets for the first time (92.000). Nori had an echocardiogram today too and it is ok. Thank you! Patr?cia Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter > escreveu: Hello Patricia, you may already be doing this - but if not, please take a copy of Amani's conversations for the vet to read - may help. Good luck - don't give up!! Sandt W On June 7, 2019 at 9:55 PM Patricia Oliveira > wrote: Nori did not want to eat by herself so they are syringing food. They started another medication for nausea, although she does not vomit, they think that may be why she does not eat. Blood work showed changes in neutrophils (bizarre core?), veternary says it can be from leukemia. The result of this transfusion was not as good as the other time :( i?ll talk to veterinary tomorrow morning again. thank you! Patr?cia Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com> escreveu: Still sounds more like a transfusion reaction than anything with the meds. Hang in there. See what the afternoon labs show. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 1:44 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani Nori is receiving doxy+prenisolone+stanazolol even in the hospital. I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don?t remember if it was icteric plasma on last one. I was hopefull she would come back home tomorrow, now i don?t know if it will be possible. Today she must have am echocardiogram too because x-ray showed an enlarged heart. Thank you! Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: Hi Patricia The Stanozolol often has a side-effect of elevating liver enzymes, though I cannot remember if it also increased bilirubin (which would be what would cause the icteric observation of the plasma). However, hang in there. If it is the Stanozolol, my experience is that the liver enzymes drop right back to normal, shortly after it is discontinued, and there is no lasting damage to the liver. For now, what you have described (low temp and slightly lower heart rate) seems more likely to be related to the transfusion itself, rather than anything else going on. It is also possible that with the additional transfusion, there is a higher than normal red cell destruction going on, which would be another explanation for the increased icterus in the blood (which will also show as an increase in bilirubin). Elevated bilirubin can often be caused by a reaction to a blood transfusion. If the high bilirubin is the indirect or the unconjugated portion, it is related to red cell break down. The direct bilirubin (conjugated portion) is related to liver function. The lab results are usually broken down to Total bilirubin and Direct bilirubin. The indirect portion is obtained by subtracting the direct amount from the total amount. I myself went through the pressure of the vets wanting me to discontinue the Stanozolol because of abnormal liver enzymes. My logic was that there was nothing else. If I discontinued the Stanozolol, my cat would die, period. I continued and found that in the end, the liver enzymes normalized on their own, even though I had Zander on almost continuous Stanozolol for close to two years. I know that you know that you are only temporarily helping Nori with blood transfusions, and the virus is still attacking cells, etc. In my opinion ? and mine alone ? my experience and research leads me to the conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell production, but I believe that the Doxycyline assisted in keeping the viruses from properly reproducing. However, anticipate that when the vet gets back the second set of blood work, she may well try to tell you to discontinue the Stanozolol. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 12:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Nori got another transfusion last night, hematocrit was 11.9 before it. Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. i am worried again. Thank you, Patr?cia Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 4, 2019 8:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Lorraine Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). :( Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston > escreveu: Patricia, I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] On Behalf Of Patricia Oliveira Sent: Tuesday, June 4, 2019 6:34 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Tue Jun 11 09:33:50 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Tue, 11 Jun 2019 11:33:50 -0300 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> <000701d52004$aaf998e0$00eccaa0$@centurytel.net> Message-ID: Yesterday hospital called me saying Nori could come home. I went there after work and, while i waited for prescriptions, she started a seizure. Vet medicated her so that seizure didn?t complete (diazepam and mannitol). I stayed with her sometime, talked to her but i felt it was a farewell. When i arrive at home, vet called me to say Nori had a cardiopulmonary arrest. They reanimated her but it could happen again. Less then 30 minutes later, they called me again to say Nori had passed away. As always happens here, when a cat has seizures, brazilian veterinarians says it is fip. I don?t know what she really had, i am very sorrow for didn?t bring her home on sunday, when she was better. At least, she would have had one more day at home, with sun bath and love. I want to thank all of you. You were the best support i could find for Nori. Thank you very much. Patr?cia Em ter, 11 de jun de 2019 ?s 00:22, Amani Oakley escreveu: > We?re all pulling for Nori. > > > > Amani > > > > *From:* Felvtalk * On Behalf Of *Ardy > Robertson > *Sent:* June 10, 2019 11:21 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hello all ? I?m following Nori?s progress and please know, I?m keeping her > in my thoughts and prayers too, hoping the Stanizolol/Doxy/Prednisolone > combo works for her. She has chosen her owners well, thank you for taking > such good care of her. And thanks Amani for the good advice as always. > > Ardy > > > > > > *From:* Felvtalk *On Behalf Of *Amani > Oakley > *Sent:* Saturday, June 8, 2019 9:23 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > One option is to ask your vet to show you how to give her subcutaneous > fluids, which I do all the time for my cats if needed. However, for now, it > makes sense to leave her there I guess. I presume they are warming the IV > fluids too, because again, with such a small kitten, it wouldn?t take much > to chill her if the fluids are at room temperature or colder. > > > > I guess it?s just me. I am pretty adamant about taking home my cats > whenever possible, but I understand that Nori sounds like she needs some > extra help. I just find that the cats respond far better to personal > cuddling and love, and this makes them feel better, eat more, etc. > > > > Hopefully, she will feel better tomorrow. > > > > I?m crossing my fingers for you and Nori. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 8, 2019 9:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > She has fluids IV all the time and replenishment of potassium. Receives > external heating too. > > > > They monitor pressure (low sometimes), oxygenation, temperature and heart > rate several times a day. > > I wish she could come home soon but she has been dehydrated even with > fluids IV. I don?t know if it is safe to bring her now. > > > > > > > > Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley > escreveu: > > Patricia > > > > I agree with you that it is too early to tell, but for sure it is good > news that the haematocrit is moving in the right direction. Very good news > on the rosy gingiva. > > > > Rouleaux is likely only due to the transfusion. She appears to have had a > bit of transfusion reaction, so the cells may be sticking to one another as > a result. (Red cells in Rouleaux formation means that the look like a stack > of coins ? one on top of the other. In humans, that presentation is > consistent with multiple myeloma. I don?t think it means anything right now > other than the new red cells may be reacting a bit with her own cells). > > > > I think she is working through the transfusion reaction, so that is likely > why she is sleeping because you said that immediately after the > transfusion, she was active and eating on her own. > > > > Low platelets are consistent with the FeLV presentation and the impact on > the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that > with my Zander, I had the red cell numbers recover first, before the > platelets recovered. > > > > I presume they have her on a heating pad to keep her body temperature up. > > > > I suspect it might be premature to look at the neurology right now. She is > working through a lot, and is a tiny kitten. She needs to be given time to > recover from the transfusion reaction, and to allow the good food and > medication to start to work. I don?t know how a neurological diagnosis > could help you now, and one would expect the neurologist will have a > difficult time seeing a true neurological deficit, with all the rest of the > stuff happening. > > > > I would also suggest that at some point, it is better for her to be with > you at home. If they are not giving her anything like fluids, you might > consider taking her home with you. I know with Zander, he reacted most > strongly when I was there with him. I could get him to play a little bit > and that made him feel better, and of course, lots of cuddles and kisses. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 8, 2019 8:52 PM > *To:* Sandra Wachtstetter ; > felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Thank you, Sandra :) > > > > I visited Nori today. The hospital is in another city so I can't go there > every day. > > > > She is a rosy gingiva, but continues to sleep most of the time and with a > low temperature. One of the veterinarians there thinks that temperature is > lower because of malnutrition, she has almost no lean mass and no fat. > > > > Nori will go through the evaluation of a neurologist tomorrow. Some > hypotheses raised for this prostration are neurological, including a > possible hypoxia before the first transfusion when her hematocrit was > really low. > > > > Her blood work today is 30% hematocrit, the higher till now! So i think > red cells aren?t being destroyed anymore, is it right or is it early to > know? > > > > Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low > platelets for the first time (92.000). > > > > Nori had an echocardiogram today too and it is ok. > > > > Thank you! > > > > Patr?cia > > > > Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter < > swacht1946 at comcast.net> escreveu: > > Hello Patricia, you may already be doing this - but if not, please take a > copy of Amani's conversations for the vet to read - may help. > > Good luck - don't give up!! > > Sandt W > > > > On June 7, 2019 at 9:55 PM Patricia Oliveira > wrote: > > Nori did not want to eat by herself so they are syringing food. They > started another medication for nausea, although she does not vomit, they > think that may be why she does not eat. > > > > Blood work showed changes in neutrophils (bizarre core?), veternary says > it can be from leukemia. > > > > The result of this transfusion was not as good as the other time :( > > > > i?ll talk to veterinary tomorrow morning again. > > > > thank you! > > > > Patr?cia > > > > > > > > Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com> > escreveu: > > Still sounds more like a transfusion reaction than anything with the meds. > > > > Hang in there. See what the afternoon labs show. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 7, 2019 1:44 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani > > > > Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > > > > I know it can be a reaction but i thought higher dose of prednisolone > would prevent hemolysis. > > > > I also know it's normal for part of the red blood cells to be cleared > right after the transfusion, but i don?t remember if it was icteric plasma > on last one. > > > > I was hopefull she would come back home tomorrow, now i don?t know if it > will be possible. > > > > Today she must have am echocardiogram too because x-ray showed an enlarged > heart. > > > > Thank you! > > > > > > > > Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: > > Hi Patricia > > > > The Stanozolol often has a side-effect of elevating liver enzymes, though > I cannot remember if it also increased bilirubin (which would be what would > cause the icteric observation of the plasma). However, hang in there. If it > is the Stanozolol, my experience is that the liver enzymes drop right back > to normal, shortly after it is discontinued, and there is no lasting damage > to the liver. For now, what you have described (low temp and slightly lower > heart rate) seems more likely to be related to the transfusion itself, > rather than anything else going on. > > > > It is also possible that with the additional transfusion, there is a > higher than normal red cell destruction going on, which would be another > explanation for the increased icterus in the blood (which will also show as > an increase in bilirubin). Elevated bilirubin can often be caused by a > reaction to a blood transfusion. If the high bilirubin is the indirect or > the unconjugated portion, it is related to red cell break down. The direct > bilirubin (conjugated portion) is related to liver function. The lab > results are usually broken down to Total bilirubin and Direct bilirubin. > The indirect portion is obtained by subtracting the direct amount from the > total amount. > > > > I myself went through the pressure of the vets wanting me to discontinue > the Stanozolol because of abnormal liver enzymes. My logic was that there > was nothing else. If I discontinued the Stanozolol, my cat would die, > period. I continued and found that in the end, the liver enzymes normalized > on their own, even though I had Zander on almost continuous Stanozolol for > close to two years. > > > > I know that you know that you are only temporarily helping Nori with blood > transfusions, and the virus is still attacking cells, etc. In my opinion ? > and mine alone ? my experience and research leads me to the conclusion that > the combination of Doxycycline/Prednisone/Stanozolol worked to not only > boost the red cell production, but I believe that the Doxycyline assisted > in keeping the viruses from properly reproducing. > > > > However, anticipate that when the vet gets back the second set of blood > work, she may well try to tell you to discontinue the Stanozolol. > > > > Amani > > > > > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 7, 2019 12:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Nori got another transfusion last night, hematocrit was 11.9 before it. > > > > Today morning, i talk to the hospital's veterinarian, she said hematocrit > went to 29 and Nori was fine, all normal parameters and eating by herself > again. > > > > But plasma was intensely icteric. I think this means red cells being > destroyed, isn't it? > > > > About one hour ago, veterinarian said Nori was with low temperature and > heart rate slightly lower than normal. She was waiting the new blood work. > In the morning, it was done only hematocrit, not complete blood work. > > > > i am worried again. > > > > Thank you, > > > > Patr?cia > > > > Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: > > I would be leery of the going the route suggested by the vet at this > juncture. I seriously seriously doubt if the erythropoietin will help. See > my earlier where I explain why. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 4, 2019 8:53 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Lorraine > > > > Veterinary wants to increase prednisolone to immunosuppressive dose and > add erythropoietin. She thinks it is immune-mediated anemia and > not mycoplasma. > > > > Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. > > > > We did x-ray today too. No visible tumor but we found a > possible cardiopathy ("Increased globular-looking heart silhouette"). > > > > :( > > > > > > > > Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < > johnston1110 at comcast.net> escreveu: > > Patricia, > > > > I would go with the transfusion and also start erythropoietin. Stanozolol > is supposed to stimulate erythropoietin production, but she might need a > boost of the ready-made drug just to keep her alive until then. > > > > - Lorraine > > > > "Sometimes it is the people no one can imagine anything of who do the > things no one can imagine." - Alan Turing > > > > *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On Behalf > Of *Patricia Oliveira > *Sent:* Tuesday, June 4, 2019 6:34 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, > > > > We did another blood work today, her hematocrit is 13% now :( > > > > She is very sleepy but responsive when i talk to her. > > > > I don?t know if i can wait some more days to see if stanozolol is working. > Or maybe it would be better get another transfusion right now. > > > > Today, vet talk about erythropoietin. Do you know if it can be used with > stanozolol? > > > > Thank you, > > > > Patr?cia > > > > Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: > > Hi Patricia ? I gave all the pills together, morning and evening, except > for the metoclopramide which was given ? or so before meals. The rest I > gave with the meals. I didn?t observe a problem with giving them together. > > > > You might also try baby food to get Nori to eat. Get the pureed kind (beef > or chicken with or without vegetables), so it can be sucked up into a > syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > medication regime), then I would use a syringe to get the baby food into > him. Baby food is easy to digest and has good things in it. I would target > ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > of syringe-fulls if possible. Eventually, Zander started eating the baby > food on his own, and then I graduated to moist food, and really, anything > he wanted until he put the weight back on. > > > > I had a look at the picture you sent and Nori is adorable. I am crossing > my fingers for you and for Nori. Keep us updated on her progress. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* June 1, 2019 12:36 PM > *To:* felvtalk at felineleukemia.org > *Subject:* Re: [Felvtalk] Rescued kitten felv + > > > > Hi, Amani! > > > > Thanky you very much for you email! > > > > Nori was discharged from the hospital yesterday night. She is eating baby > dry food. I tried canned but she didn?t accept so weel. > > > > Today i bought other kinds of canned, i'll try them hoping she likes some > one. > > > > Compound pharmacy must delivery stanozolol today. > > > > Are there any precautions regarding medication schedules? Close or far to > doxy, for example? > > > > This is Nori: > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > > > > > > > Thank you! > > > > Patr?cia > > > > Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: > > Sorry Patricia ? after going on and on in my last email, I realized I > hadn?t actually answered your question. I think you can probably use the > stanozolol with the Doxycycline, without the prednisone, but prednisone > itself has properties which help to boost red cell production. Try it out, > keep close tabs on the haematology results and see if you are getting a > good response on just Doxycycline and the Stanozolol. If not, add the > prednisone. You may find that this combination assists with the FIP as > well, as per my previous email. > > > > Amani > > > > *From:* Felvtalk *On Behalf Of *Patricia > Oliveira > *Sent:* May 30, 2019 12:56 PM > *To:* felvtalk at felineleukemia.org > *Subject:* [Felvtalk] Rescued kitten felv + > > > > Hi from Brazil, > > > > I rescued a very weak, dehydrated, extremely thin kitten. > > > She's hospitalized now. Her hematocrit was 8, had blood transfusion which > raised hematocrit to 22, now it is 19. Low reticulocyte count. > > She has difficulty walking, which we can not define if it is just weakness > or neurological. Already had a seizure. > > She also have changes in her kidneys. It has been tested and is felv + > > She is receiving doxy and the hospital vets would like to include > prednisolone. > > However, as it is not possible yet to rule out PIF, and the medication I > could use in the case of PIF does not work if the cat received > prednisolone, I am trying to avoid it. > > The veterinarian agreed to prescribe stanozolol. > > Can it be used without prednisolone, only with doxy she is already > receiving? > > Thank you! > > > > Patr?cia > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From thyme2sail at gmail.com Tue Jun 11 09:55:23 2019 From: thyme2sail at gmail.com (Pam Doore) Date: Tue, 11 Jun 2019 10:55:23 -0400 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> <000701d52004$aaf998e0$00eccaa0$@centurytel.net> Message-ID: You have my deepest sympathy Patricia! I am so so sorry! ~~@~~~~~@~~~~~@~~~~~@~~~~~@~~~~ *Christ beside me, Christ before me, Christ behind me, Christ within me, Christ beneath me, Christ above me. ? **St. Patrick* On Tue, Jun 11, 2019 at 10:34 AM Patricia Oliveira wrote: > Yesterday hospital called me saying Nori could come home. I went there > after work and, while i waited for prescriptions, she started a seizure. > > Vet medicated her so that seizure didn?t complete (diazepam and mannitol). > > I stayed with her sometime, talked to her but i felt it was a farewell. > > When i arrive at home, vet called me to say Nori had a cardiopulmonary > arrest. They reanimated her but it could happen again. > > Less then 30 minutes later, they called me again to say Nori had passed > away. > > As always happens here, when a cat has seizures, brazilian veterinarians > says it is fip. > > I don?t know what she really had, i am very sorrow for didn?t bring her > home on sunday, when she was better. At least, she would have had one more > day at home, with sun bath and love. > > I want to thank all of you. You were the best support i could find for > Nori. > > Thank you very much. > > > Patr?cia > > Em ter, 11 de jun de 2019 ?s 00:22, Amani Oakley > escreveu: > >> We?re all pulling for Nori. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk * On Behalf Of *Ardy >> Robertson >> *Sent:* June 10, 2019 11:21 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Hello all ? I?m following Nori?s progress and please know, I?m keeping >> her in my thoughts and prayers too, hoping the Stanizolol/Doxy/Prednisolone >> combo works for her. She has chosen her owners well, thank you for taking >> such good care of her. And thanks Amani for the good advice as always. >> >> Ardy >> >> >> >> >> >> *From:* Felvtalk *On Behalf Of *Amani >> Oakley >> *Sent:* Saturday, June 8, 2019 9:23 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> One option is to ask your vet to show you how to give her subcutaneous >> fluids, which I do all the time for my cats if needed. However, for now, it >> makes sense to leave her there I guess. I presume they are warming the IV >> fluids too, because again, with such a small kitten, it wouldn?t take much >> to chill her if the fluids are at room temperature or colder. >> >> >> >> I guess it?s just me. I am pretty adamant about taking home my cats >> whenever possible, but I understand that Nori sounds like she needs some >> extra help. I just find that the cats respond far better to personal >> cuddling and love, and this makes them feel better, eat more, etc. >> >> >> >> Hopefully, she will feel better tomorrow. >> >> >> >> I?m crossing my fingers for you and Nori. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* June 8, 2019 9:53 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> She has fluids IV all the time and replenishment of potassium. Receives >> external heating too. >> >> >> >> They monitor pressure (low sometimes), oxygenation, temperature and heart >> rate several times a day. >> >> I wish she could come home soon but she has been dehydrated even with >> fluids IV. I don?t know if it is safe to bring her now. >> >> >> >> >> >> >> >> Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley >> escreveu: >> >> Patricia >> >> >> >> I agree with you that it is too early to tell, but for sure it is good >> news that the haematocrit is moving in the right direction. Very good news >> on the rosy gingiva. >> >> >> >> Rouleaux is likely only due to the transfusion. She appears to have had a >> bit of transfusion reaction, so the cells may be sticking to one another as >> a result. (Red cells in Rouleaux formation means that the look like a stack >> of coins ? one on top of the other. In humans, that presentation is >> consistent with multiple myeloma. I don?t think it means anything right now >> other than the new red cells may be reacting a bit with her own cells). >> >> >> >> I think she is working through the transfusion reaction, so that is >> likely why she is sleeping because you said that immediately after the >> transfusion, she was active and eating on her own. >> >> >> >> Low platelets are consistent with the FeLV presentation and the impact on >> the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that >> with my Zander, I had the red cell numbers recover first, before the >> platelets recovered. >> >> >> >> I presume they have her on a heating pad to keep her body temperature up. >> >> >> >> I suspect it might be premature to look at the neurology right now. She >> is working through a lot, and is a tiny kitten. She needs to be given time >> to recover from the transfusion reaction, and to allow the good food and >> medication to start to work. I don?t know how a neurological diagnosis >> could help you now, and one would expect the neurologist will have a >> difficult time seeing a true neurological deficit, with all the rest of the >> stuff happening. >> >> >> >> I would also suggest that at some point, it is better for her to be with >> you at home. If they are not giving her anything like fluids, you might >> consider taking her home with you. I know with Zander, he reacted most >> strongly when I was there with him. I could get him to play a little bit >> and that made him feel better, and of course, lots of cuddles and kisses. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* June 8, 2019 8:52 PM >> *To:* Sandra Wachtstetter ; >> felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Thank you, Sandra :) >> >> >> >> I visited Nori today. The hospital is in another city so I can't go there >> every day. >> >> >> >> She is a rosy gingiva, but continues to sleep most of the time and with a >> low temperature. One of the veterinarians there thinks that temperature is >> lower because of malnutrition, she has almost no lean mass and no fat. >> >> >> >> Nori will go through the evaluation of a neurologist tomorrow. Some >> hypotheses raised for this prostration are neurological, including a >> possible hypoxia before the first transfusion when her hematocrit was >> really low. >> >> >> >> Her blood work today is 30% hematocrit, the higher till now! So i think >> red cells aren?t being destroyed anymore, is it right or is it early to >> know? >> >> >> >> Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low >> platelets for the first time (92.000). >> >> >> >> Nori had an echocardiogram today too and it is ok. >> >> >> >> Thank you! >> >> >> >> Patr?cia >> >> >> >> Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter < >> swacht1946 at comcast.net> escreveu: >> >> Hello Patricia, you may already be doing this - but if not, please take a >> copy of Amani's conversations for the vet to read - may help. >> >> Good luck - don't give up!! >> >> Sandt W >> >> >> >> On June 7, 2019 at 9:55 PM Patricia Oliveira >> wrote: >> >> Nori did not want to eat by herself so they are syringing food. They >> started another medication for nausea, although she does not vomit, they >> think that may be why she does not eat. >> >> >> >> Blood work showed changes in neutrophils (bizarre core?), veternary says >> it can be from leukemia. >> >> >> >> The result of this transfusion was not as good as the other time :( >> >> >> >> i?ll talk to veterinary tomorrow morning again. >> >> >> >> thank you! >> >> >> >> Patr?cia >> >> >> >> >> >> >> >> Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com> >> escreveu: >> >> Still sounds more like a transfusion reaction than anything with the meds. >> >> >> >> Hang in there. See what the afternoon labs show. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* June 7, 2019 1:44 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Hi, Amani >> >> >> >> Nori is receiving doxy+prenisolone+stanazolol even in the hospital. >> >> >> >> I know it can be a reaction but i thought higher dose of prednisolone >> would prevent hemolysis. >> >> >> >> I also know it's normal for part of the red blood cells to be cleared >> right after the transfusion, but i don?t remember if it was icteric plasma >> on last one. >> >> >> >> I was hopefull she would come back home tomorrow, now i don?t know if it >> will be possible. >> >> >> >> Today she must have am echocardiogram too because x-ray showed an >> enlarged heart. >> >> >> >> Thank you! >> >> >> >> >> >> >> >> Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley >> escreveu: >> >> Hi Patricia >> >> >> >> The Stanozolol often has a side-effect of elevating liver enzymes, though >> I cannot remember if it also increased bilirubin (which would be what would >> cause the icteric observation of the plasma). However, hang in there. If it >> is the Stanozolol, my experience is that the liver enzymes drop right back >> to normal, shortly after it is discontinued, and there is no lasting damage >> to the liver. For now, what you have described (low temp and slightly lower >> heart rate) seems more likely to be related to the transfusion itself, >> rather than anything else going on. >> >> >> >> It is also possible that with the additional transfusion, there is a >> higher than normal red cell destruction going on, which would be another >> explanation for the increased icterus in the blood (which will also show as >> an increase in bilirubin). Elevated bilirubin can often be caused by a >> reaction to a blood transfusion. If the high bilirubin is the indirect or >> the unconjugated portion, it is related to red cell break down. The direct >> bilirubin (conjugated portion) is related to liver function. The lab >> results are usually broken down to Total bilirubin and Direct bilirubin. >> The indirect portion is obtained by subtracting the direct amount from the >> total amount. >> >> >> >> I myself went through the pressure of the vets wanting me to discontinue >> the Stanozolol because of abnormal liver enzymes. My logic was that there >> was nothing else. If I discontinued the Stanozolol, my cat would die, >> period. I continued and found that in the end, the liver enzymes normalized >> on their own, even though I had Zander on almost continuous Stanozolol for >> close to two years. >> >> >> >> I know that you know that you are only temporarily helping Nori with >> blood transfusions, and the virus is still attacking cells, etc. In my >> opinion ? and mine alone ? my experience and research leads me to the >> conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked >> to not only boost the red cell production, but I believe that the >> Doxycyline assisted in keeping the viruses from properly reproducing. >> >> >> >> However, anticipate that when the vet gets back the second set of blood >> work, she may well try to tell you to discontinue the Stanozolol. >> >> >> >> Amani >> >> >> >> >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* June 7, 2019 12:53 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Hi, Amani! >> >> >> >> Nori got another transfusion last night, hematocrit was 11.9 before it. >> >> >> >> Today morning, i talk to the hospital's veterinarian, she said hematocrit >> went to 29 and Nori was fine, all normal parameters and eating by herself >> again. >> >> >> >> But plasma was intensely icteric. I think this means red cells being >> destroyed, isn't it? >> >> >> >> About one hour ago, veterinarian said Nori was with low temperature and >> heart rate slightly lower than normal. She was waiting the new blood work. >> In the morning, it was done only hematocrit, not complete blood work. >> >> >> >> i am worried again. >> >> >> >> Thank you, >> >> >> >> Patr?cia >> >> >> >> Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley >> escreveu: >> >> I would be leery of the going the route suggested by the vet at this >> juncture. I seriously seriously doubt if the erythropoietin will help. See >> my earlier where I explain why. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* June 4, 2019 8:53 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Hi, Lorraine >> >> >> >> Veterinary wants to increase prednisolone to immunosuppressive dose and >> add erythropoietin. She thinks it is immune-mediated anemia and >> not mycoplasma. >> >> >> >> Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 >> kg. >> >> >> >> We did x-ray today too. No visible tumor but we found a >> possible cardiopathy ("Increased globular-looking heart silhouette"). >> >> >> >> :( >> >> >> >> >> >> >> >> Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < >> johnston1110 at comcast.net> escreveu: >> >> Patricia, >> >> >> >> I would go with the transfusion and also start erythropoietin. >> Stanozolol is supposed to stimulate erythropoietin production, but she >> might need a boost of the ready-made drug just to keep her alive until then. >> >> >> >> - Lorraine >> >> >> >> "Sometimes it is the people no one can imagine anything of who do the >> things no one can imagine." - Alan Turing >> >> >> >> *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On Behalf >> Of *Patricia Oliveira >> *Sent:* Tuesday, June 4, 2019 6:34 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Hi, >> >> >> >> We did another blood work today, her hematocrit is 13% now :( >> >> >> >> She is very sleepy but responsive when i talk to her. >> >> >> >> I don?t know if i can wait some more days to see if stanozolol is >> working. Or maybe it would be better get another transfusion right now. >> >> >> >> Today, vet talk about erythropoietin. Do you know if it can be used with >> stanozolol? >> >> >> >> Thank you, >> >> >> >> Patr?cia >> >> >> >> Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley >> escreveu: >> >> Hi Patricia ? I gave all the pills together, morning and evening, except >> for the metoclopramide which was given ? or so before meals. The rest I >> gave with the meals. I didn?t observe a problem with giving them together. >> >> >> >> You might also try baby food to get Nori to eat. Get the pureed kind >> (beef or chicken with or without vegetables), so it can be sucked up into a >> syringe. If my Zander wasn?t eating (and he wasn?t at the start of the >> medication regime), then I would use a syringe to get the baby food into >> him. Baby food is easy to digest and has good things in it. I would target >> ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number >> of syringe-fulls if possible. Eventually, Zander started eating the baby >> food on his own, and then I graduated to moist food, and really, anything >> he wanted until he put the weight back on. >> >> >> >> I had a look at the picture you sent and Nori is adorable. I am crossing >> my fingers for you and for Nori. Keep us updated on her progress. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* June 1, 2019 12:36 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* Re: [Felvtalk] Rescued kitten felv + >> >> >> >> Hi, Amani! >> >> >> >> Thanky you very much for you email! >> >> >> >> Nori was discharged from the hospital yesterday night. She is eating baby >> dry food. I tried canned but she didn?t accept so weel. >> >> >> >> Today i bought other kinds of canned, i'll try them hoping she likes some >> one. >> >> >> >> Compound pharmacy must delivery stanozolol today. >> >> >> >> Are there any precautions regarding medication schedules? Close or far to >> doxy, for example? >> >> >> >> This is Nori: >> https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html >> >> >> >> >> >> >> Thank you! >> >> >> >> Patr?cia >> >> >> >> Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley >> escreveu: >> >> Sorry Patricia ? after going on and on in my last email, I realized I >> hadn?t actually answered your question. I think you can probably use the >> stanozolol with the Doxycycline, without the prednisone, but prednisone >> itself has properties which help to boost red cell production. Try it out, >> keep close tabs on the haematology results and see if you are getting a >> good response on just Doxycycline and the Stanozolol. If not, add the >> prednisone. You may find that this combination assists with the FIP as >> well, as per my previous email. >> >> >> >> Amani >> >> >> >> *From:* Felvtalk *On Behalf Of *Patricia >> Oliveira >> *Sent:* May 30, 2019 12:56 PM >> *To:* felvtalk at felineleukemia.org >> *Subject:* [Felvtalk] Rescued kitten felv + >> >> >> >> Hi from Brazil, >> >> >> >> I rescued a very weak, dehydrated, extremely thin kitten. >> >> >> She's hospitalized now. Her hematocrit was 8, had blood transfusion which >> raised hematocrit to 22, now it is 19. Low reticulocyte count. >> >> She has difficulty walking, which we can not define if it is just >> weakness or neurological. Already had a seizure. >> >> She also have changes in her kidneys. It has been tested and is felv + >> >> She is receiving doxy and the hospital vets would like to include >> prednisolone. >> >> However, as it is not possible yet to rule out PIF, and the medication I >> could use in the case of PIF does not work if the cat received >> prednisolone, I am trying to avoid it. >> >> The veterinarian agreed to prescribe stanozolol. >> >> Can it be used without prednisolone, only with doxy she is already >> receiving? >> >> Thank you! >> >> >> >> Patr?cia >> >> _______________________________________________ >> Felvtalk mailing list >> Felvtalk at felineleukemia.org >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org >> >> _______________________________________________ >> Felvtalk mailing list >> Felvtalk at felineleukemia.org >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org >> >> _______________________________________________ >> Felvtalk mailing list >> Felvtalk at felineleukemia.org >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org >> >> _______________________________________________ >> Felvtalk mailing list >> Felvtalk at felineleukemia.org >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org >> > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From bchapel at optonline.net Tue Jun 11 10:30:55 2019 From: bchapel at optonline.net (ROBERT CHAPEL) Date: Tue, 11 Jun 2019 11:30:55 -0400 (EDT) Subject: [Felvtalk] Felvtalk Digest, Vol 55, Issue 26 In-Reply-To: References: Message-ID: <162623946.28910.1560267055531@mymail.optimum.net> I can't imagine anyone working harder to save a kittens life than you have Patricia.... I'm sure we are ALL so sorry that it was not successful... FeLV is such a terrible disease and your poor little girl has so many complications... Bob > On June 11, 2019 at 10:56 AM felvtalk-request at felineleukemia.org mailto:felvtalk-request at felineleukemia.org wrote: > > > Send Felvtalk mailing list submissions to > felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > > To subscribe or unsubscribe via the World Wide Web, visit > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > or, via email, send a message with subject or body 'help' to > felvtalk-request at felineleukemia.org mailto:felvtalk-request at felineleukemia.org > > You can reach the person managing the list at > felvtalk-owner at felineleukemia.org mailto:felvtalk-owner at felineleukemia.org > > When replying, please edit your Subject line so it is more specific > than "Re: Contents of Felvtalk digest..." > > > Today's Topics: > 1. Re: Rescued kitten felv + (Pam Doore) > > > ---------------------------------------------------------------------- > > Message: 1 > Date: Tue, 11 Jun 2019 10:55:23 -0400 > From: Pam Doore > To: felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > Message-ID: > > Content-Type: text/plain; charset="utf-8" > > You have my deepest sympathy Patricia! I am so so sorry! > > ~~@~~~~~@~~~~~@~~~~~@~~~~~@~~~~ > > *Christ beside me, Christ before me, Christ behind me, Christ within me, > Christ beneath me, Christ above me. ? **St. Patrick* > > > > On Tue, Jun 11, 2019 at 10:34 AM Patricia Oliveira > wrote: > > > > Yesterday hospital called me saying Nori could come home. I went there > > after work and, while i waited for prescriptions, she started a seizure. > > > > > > > > Vet medicated her so that seizure didn?t complete (diazepam and mannitol). > > > > > > > > I stayed with her sometime, talked to her but i felt it was a farewell. > > > > > > > > When i arrive at home, vet called me to say Nori had a cardiopulmonary > > arrest. They reanimated her but it could happen again. > > > > > > > > Less then 30 minutes later, they called me again to say Nori had passed > > away. > > > > > > > > As always happens here, when a cat has seizures, brazilian veterinarians > > says it is fip. > > > > > > > > I don?t know what she really had, i am very sorrow for didn?t bring her > > home on sunday, when she was better. At least, she would have had one more > > day at home, with sun bath and love. > > > > > > > > I want to thank all of you. You were the best support i could find for > > Nori. > > > > > > > > Thank you very much. > > > > > > > > > > Patr?cia > > > > > > > > Em ter, 11 de jun de 2019 ?s 00:22, Amani Oakley > > escreveu: > > > > > >> We?re all pulling for Nori. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk * On Behalf Of *Ardy > >> Robertson > >> *Sent:* June 10, 2019 11:21 PM > >> *To:* felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hello all ? I?m following Nori?s progress and please know, I?m keeping > >> her in my thoughts and prayers too, hoping the Stanizolol/Doxy/Prednisolone > >> combo works for her. She has chosen her owners well, thank you for taking > >> such good care of her. And thanks Amani for the good advice as always. > >> > >> Ardy > >> > >> > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of *Amani > >> Oakley > >> *Sent:* Saturday, June 8, 2019 9:23 PM > >> *To:* felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> One option is to ask your vet to show you how to give her subcutaneous > >> fluids, which I do all the time for my cats if needed. However, for now, it > >> makes sense to leave her there I guess. I presume they are warming the IV > >> fluids too, because again, with such a small kitten, it wouldn?t take much > >> to chill her if the fluids are at room temperature or colder. > >> > >> > >> > >> I guess it?s just me. I am pretty adamant about taking home my cats > >> whenever possible, but I understand that Nori sounds like she needs some > >> extra help. I just find that the cats respond far better to personal > >> cuddling and love, and this makes them feel better, eat more, etc. > >> > >> > >> > >> Hopefully, she will feel better tomorrow. > >> > >> > >> > >> I?m crossing my fingers for you and Nori. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of *Patricia > >> Oliveira > >> *Sent:* June 8, 2019 9:53 PM > >> *To:* felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> She has fluids IV all the time and replenishment of potassium. Receives > >> external heating too. > >> > >> > >> > >> They monitor pressure (low sometimes), oxygenation, temperature and heart > >> rate several times a day. > >> > >> I wish she could come home soon but she has been dehydrated even with > >> fluids IV. I don?t know if it is safe to bring her now. > >> > >> > >> > >> > >> > >> > >> > >> Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley > >> escreveu: > >> > >> Patricia > >> > >> > >> > >> I agree with you that it is too early to tell, but for sure it is good > >> news that the haematocrit is moving in the right direction. Very good news > >> on the rosy gingiva. > >> > >> > >> > >> Rouleaux is likely only due to the transfusion. She appears to have had a > >> bit of transfusion reaction, so the cells may be sticking to one another as > >> a result. (Red cells in Rouleaux formation means that the look like a stack > >> of coins ? one on top of the other. In humans, that presentation is > >> consistent with multiple myeloma. I don?t think it means anything right now > >> other than the new red cells may be reacting a bit with her own cells). > >> > >> > >> > >> I think she is working through the transfusion reaction, so that is > >> likely why she is sleeping because you said that immediately after the > >> transfusion, she was active and eating on her own. > >> > >> > >> > >> Low platelets are consistent with the FeLV presentation and the impact on > >> the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that > >> with my Zander, I had the red cell numbers recover first, before the > >> platelets recovered. > >> > >> > >> > >> I presume they have her on a heating pad to keep her body temperature up. > >> > >> > >> > >> I suspect it might be premature to look at the neurology right now. She > >> is working through a lot, and is a tiny kitten. She needs to be given time > >> to recover from the transfusion reaction, and to allow the good food and > >> medication to start to work. I don?t know how a neurological diagnosis > >> could help you now, and one would expect the neurologist will have a > >> difficult time seeing a true neurological deficit, with all the rest of the > >> stuff happening. > >> > >> > >> > >> I would also suggest that at some point, it is better for her to be with > >> you at home. If they are not giving her anything like fluids, you might > >> consider taking her home with you. I know with Zander, he reacted most > >> strongly when I was there with him. I could get him to play a little bit > >> and that made him feel better, and of course, lots of cuddles and kisses. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of *Patricia > >> Oliveira > >> *Sent:* June 8, 2019 8:52 PM > >> *To:* Sandra Wachtstetter ; > >> felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Thank you, Sandra :) > >> > >> > >> > >> I visited Nori today. The hospital is in another city so I can't go there > >> every day. > >> > >> > >> > >> She is a rosy gingiva, but continues to sleep most of the time and with a > >> low temperature. One of the veterinarians there thinks that temperature is > >> lower because of malnutrition, she has almost no lean mass and no fat. > >> > >> > >> > >> Nori will go through the evaluation of a neurologist tomorrow. Some > >> hypotheses raised for this prostration are neurological, including a > >> possible hypoxia before the first transfusion when her hematocrit was > >> really low. > >> > >> > >> > >> Her blood work today is 30% hematocrit, the higher till now! So i think > >> red cells aren?t being destroyed anymore, is it right or is it early to > >> know? > >> > >> > >> > >> Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low > >> platelets for the first time (92.000). > >> > >> > >> > >> Nori had an echocardiogram today too and it is ok. > >> > >> > >> > >> Thank you! > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter < > >> swacht1946 at comcast.net mailto:swacht1946 at comcast.net > escreveu: > >> > >> Hello Patricia, you may already be doing this - but if not, please take a > >> copy of Amani's conversations for the vet to read - may help. > >> > >> Good luck - don't give up!! > >> > >> Sandt W > >> > >> > >> > >> On June 7, 2019 at 9:55 PM Patricia Oliveira > >> wrote: > >> > >> Nori did not want to eat by herself so they are syringing food. They > >> started another medication for nausea, although she does not vomit, they > >> think that may be why she does not eat. > >> > >> > >> > >> Blood work showed changes in neutrophils (bizarre core?), veternary says > >> it can be from leukemia. > >> > >> > >> > >> The result of this transfusion was not as good as the other time :( > >> > >> > >> > >> i?ll talk to veterinary tomorrow morning again. > >> > >> > >> > >> thank you! > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> > >> > >> > >> > >> Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com mailto:aoakley at oakleylegal.com > > >> escreveu: > >> > >> Still sounds more like a transfusion reaction than anything with the meds. > >> > >> > >> > >> Hang in there. See what the afternoon labs show. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of *Patricia > >> Oliveira > >> *Sent:* June 7, 2019 1:44 PM > >> *To:* felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Amani > >> > >> > >> > >> Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > >> > >> > >> > >> I know it can be a reaction but i thought higher dose of prednisolone > >> would prevent hemolysis. > >> > >> > >> > >> I also know it's normal for part of the red blood cells to be cleared > >> right after the transfusion, but i don?t remember if it was icteric plasma > >> on last one. > >> > >> > >> > >> I was hopefull she would come back home tomorrow, now i don?t know if it > >> will be possible. > >> > >> > >> > >> Today she must have am echocardiogram too because x-ray showed an > >> enlarged heart. > >> > >> > >> > >> Thank you! > >> > >> > >> > >> > >> > >> > >> > >> Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > >> escreveu: > >> > >> Hi Patricia > >> > >> > >> > >> The Stanozolol often has a side-effect of elevating liver enzymes, though > >> I cannot remember if it also increased bilirubin (which would be what would > >> cause the icteric observation of the plasma). However, hang in there. If it > >> is the Stanozolol, my experience is that the liver enzymes drop right back > >> to normal, shortly after it is discontinued, and there is no lasting damage > >> to the liver. For now, what you have described (low temp and slightly lower > >> heart rate) seems more likely to be related to the transfusion itself, > >> rather than anything else going on. > >> > >> > >> > >> It is also possible that with the additional transfusion, there is a > >> higher than normal red cell destruction going on, which would be another > >> explanation for the increased icterus in the blood (which will also show as > >> an increase in bilirubin). Elevated bilirubin can often be caused by a > >> reaction to a blood transfusion. If the high bilirubin is the indirect or > >> the unconjugated portion, it is related to red cell break down. The direct > >> bilirubin (conjugated portion) is related to liver function. The lab > >> results are usually broken down to Total bilirubin and Direct bilirubin. > >> The indirect portion is obtained by subtracting the direct amount from the > >> total amount. > >> > >> > >> > >> I myself went through the pressure of the vets wanting me to discontinue > >> the Stanozolol because of abnormal liver enzymes. My logic was that there > >> was nothing else. If I discontinued the Stanozolol, my cat would die, > >> period. I continued and found that in the end, the liver enzymes normalized > >> on their own, even though I had Zander on almost continuous Stanozolol for > >> close to two years. > >> > >> > >> > >> I know that you know that you are only temporarily helping Nori with > >> blood transfusions, and the virus is still attacking cells, etc. In my > >> opinion ? and mine alone ? my experience and research leads me to the > >> conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked > >> to not only boost the red cell production, but I believe that the > >> Doxycyline assisted in keeping the viruses from properly reproducing. > >> > >> > >> > >> However, anticipate that when the vet gets back the second set of blood > >> work, she may well try to tell you to discontinue the Stanozolol. > >> > >> > >> > >> Amani > >> > >> > >> > >> > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of *Patricia > >> Oliveira > >> *Sent:* June 7, 2019 12:53 PM > >> *To:* felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Amani! > >> > >> > >> > >> Nori got another transfusion last night, hematocrit was 11.9 before it. > >> > >> > >> > >> Today morning, i talk to the hospital's veterinarian, she said hematocrit > >> went to 29 and Nori was fine, all normal parameters and eating by herself > >> again. > >> > >> > >> > >> But plasma was intensely icteric. I think this means red cells being > >> destroyed, isn't it? > >> > >> > >> > >> About one hour ago, veterinarian said Nori was with low temperature and > >> heart rate slightly lower than normal. She was waiting the new blood work. > >> In the morning, it was done only hematocrit, not complete blood work. > >> > >> > >> > >> i am worried again. > >> > >> > >> > >> Thank you, > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > >> escreveu: > >> > >> I would be leery of the going the route suggested by the vet at this > >> juncture. I seriously seriously doubt if the erythropoietin will help. See > >> my earlier where I explain why. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of *Patricia > >> Oliveira > >> *Sent:* June 4, 2019 8:53 PM > >> *To:* felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Lorraine > >> > >> > >> > >> Veterinary wants to increase prednisolone to immunosuppressive dose and > >> add erythropoietin. She thinks it is immune-mediated anemia and > >> not mycoplasma. > >> > >> > >> > >> Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 > >> kg. > >> > >> > >> > >> We did x-ray today too. No visible tumor but we found a > >> possible cardiopathy ("Increased globular-looking heart silhouette"). > >> > >> > >> > >> :( > >> > >> > >> > >> > >> > >> > >> > >> Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < > >> johnston1110 at comcast.net mailto:johnston1110 at comcast.net > escreveu: > >> > >> Patricia, > >> > >> > >> > >> I would go with the transfusion and also start erythropoietin. > >> Stanozolol is supposed to stimulate erythropoietin production, but she > >> might need a boost of the ready-made drug just to keep her alive until then. > >> > >> > >> > >> - Lorraine > >> > >> > >> > >> "Sometimes it is the people no one can imagine anything of who do the > >> things no one can imagine." - Alan Turing > >> > >> > >> > >> *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org mailto:felvtalk-bounces at felineleukemia.org ] *On Behalf > >> Of *Patricia Oliveira > >> *Sent:* Tuesday, June 4, 2019 6:34 PM > >> *To:* felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, > >> > >> > >> > >> We did another blood work today, her hematocrit is 13% now :( > >> > >> > >> > >> She is very sleepy but responsive when i talk to her. > >> > >> > >> > >> I don?t know if i can wait some more days to see if stanozolol is > >> working. Or maybe it would be better get another transfusion right now. > >> > >> > >> > >> Today, vet talk about erythropoietin. Do you know if it can be used with > >> stanozolol? > >> > >> > >> > >> Thank you, > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > >> escreveu: > >> > >> Hi Patricia ? I gave all the pills together, morning and evening, except > >> for the metoclopramide which was given ? or so before meals. The rest I > >> gave with the meals. I didn?t observe a problem with giving them together. > >> > >> > >> > >> You might also try baby food to get Nori to eat. Get the pureed kind > >> (beef or chicken with or without vegetables), so it can be sucked up into a > >> syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > >> medication regime), then I would use a syringe to get the baby food into > >> him. Baby food is easy to digest and has good things in it. I would target > >> ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number > >> of syringe-fulls if possible. Eventually, Zander started eating the baby > >> food on his own, and then I graduated to moist food, and really, anything > >> he wanted until he put the weight back on. > >> > >> > >> > >> I had a look at the picture you sent and Nori is adorable. I am crossing > >> my fingers for you and for Nori. Keep us updated on her progress. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of *Patricia > >> Oliveira > >> *Sent:* June 1, 2019 12:36 PM > >> *To:* felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Amani! > >> > >> > >> > >> Thanky you very much for you email! > >> > >> > >> > >> Nori was discharged from the hospital yesterday night. She is eating baby > >> dry food. I tried canned but she didn?t accept so weel. > >> > >> > >> > >> Today i bought other kinds of canned, i'll try them hoping she likes some > >> one. > >> > >> > >> > >> Compound pharmacy must delivery stanozolol today. > >> > >> > >> > >> Are there any precautions regarding medication schedules? Close or far to > >> doxy, for example? > >> > >> > >> > >> This is Nori: > >> https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > >> > >> > >> > >> > >> > >> > >> Thank you! > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > >> escreveu: > >> > >> Sorry Patricia ? after going on and on in my last email, I realized I > >> hadn?t actually answered your question. I think you can probably use the > >> stanozolol with the Doxycycline, without the prednisone, but prednisone > >> itself has properties which help to boost red cell production. Try it out, > >> keep close tabs on the haematology results and see if you are getting a > >> good response on just Doxycycline and the Stanozolol. If not, add the > >> prednisone. You may find that this combination assists with the FIP as > >> well, as per my previous email. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of *Patricia > >> Oliveira > >> *Sent:* May 30, 2019 12:56 PM > >> *To:* felvtalk at felineleukemia.org mailto:felvtalk at felineleukemia.org > >> *Subject:* [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi from Brazil, > >> > >> > >> > >> I rescued a very weak, dehydrated, extremely thin kitten. > >> > >> > >> She's hospitalized now. Her hematocrit was 8, had blood transfusion which > >> raised hematocrit to 22, now it is 19. Low reticulocyte count. > >> > >> She has difficulty walking, which we can not define if it is just > >> weakness or neurological. Already had a seizure. > >> > >> She also have changes in her kidneys. It has been tested and is felv + > >> > >> She is receiving doxy and the hospital vets would like to include > >> prednisolone. > >> > >> However, as it is not possible yet to rule out PIF, and the medication I > >> could use in the case of PIF does not work if the cat received > >> prednisolone, I am trying to avoid it. > >> > >> The veterinarian agreed to prescribe stanozolol. > >> > >> Can it be used without prednisolone, only with doxy she is already > >> receiving? > >> > >> Thank you! > >> > >> > >> > >> Patr?cia > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > > > > _______________________________________________ > > Felvtalk mailing list > > Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > > > -------------- next part -------------- > An HTML attachment was scrubbed... > URL: > > ------------------------------ > > Subject: Digest Footer > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org mailto:Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > ------------------------------ > > End of Felvtalk Digest, Vol 55, Issue 26 > **************************************** > -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Tue Jun 11 19:25:35 2019 From: johnston1110 at comcast.net (Lorraine Johnston) Date: Tue, 11 Jun 2019 20:25:35 -0400 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> <000701d52004$aaf998e0$00eccaa0$@centurytel.net> Message-ID: <004301d520b5$5be6f610$13b4e230$@net> Dear Patricia, I am so sorry about Nori dying. She was a very lucky girl to have had you to help her at the end of her life. Sadly, - Lorraine . . . . . . . . . . . . . . . . Yesterday hospital called me saying Nori could come home. I went there after work and, while i waited for prescriptions, she started a seizure. Vet medicated her so that seizure didn?t complete (diazepam and mannitol). I stayed with her sometime, talked to her but i felt it was a farewell. When i arrive at home, vet called me to say Nori had a cardiopulmonary arrest. They reanimated her but it could happen again. Less then 30 minutes later, they called me again to say Nori had passed away. As always happens here, when a cat has seizures, brazilian veterinarians says it is fip. I don?t know what she really had, i am very sorrow for didn?t bring her home on sunday, when she was better. At least, she would have had one more day at home, with sun bath and love. I want to thank all of you. You were the best support i could find for Nori. Thank you very much. Patr?cia -------------- next part -------------- An HTML attachment was scrubbed... URL: From cinzaeamarelo at gmail.com Wed Jun 12 18:36:41 2019 From: cinzaeamarelo at gmail.com (Patricia Oliveira) Date: Wed, 12 Jun 2019 20:36:41 -0300 Subject: [Felvtalk] Felvtalk Digest, Vol 55, Issue 26 In-Reply-To: <162623946.28910.1560267055531@mymail.optimum.net> References: <162623946.28910.1560267055531@mymail.optimum.net> Message-ID: Thank you, Bob. Em ter, 11 de jun de 2019 ?s 12:31, ROBERT CHAPEL escreveu: > I can't imagine anyone working harder to save a kittens life than you have > Patricia.... I'm sure we are ALL so sorry that it was not successful... > FeLV is such a terrible disease and your poor little girl has so many > complications... > Bob > > On June 11, 2019 at 10:56 AM felvtalk-request at felineleukemia.org wrote: > > > Send Felvtalk mailing list submissions to > felvtalk at felineleukemia.org > > To subscribe or unsubscribe via the World Wide Web, visit > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > or, via email, send a message with subject or body 'help' to > felvtalk-request at felineleukemia.org > > You can reach the person managing the list at > felvtalk-owner at felineleukemia.org > > When replying, please edit your Subject line so it is more specific > than "Re: Contents of Felvtalk digest..." > > > Today's Topics: > 1. Re: Rescued kitten felv + (Pam Doore) > > > ---------------------------------------------------------------------- > > Message: 1 > Date: Tue, 11 Jun 2019 10:55:23 -0400 > From: Pam Doore > To: felvtalk at felineleukemia.org > Subject: Re: [Felvtalk] Rescued kitten felv + > Message-ID: > > Content-Type: text/plain; charset="utf-8" > > You have my deepest sympathy Patricia! I am so so sorry! > > ~~@~~~~~@~~~~~@~~~~~@~~~~~@~~~~ > > *Christ beside me, Christ before me, Christ behind me, Christ within me, > Christ beneath me, Christ above me. ? **St. Patrick* > > > > On Tue, Jun 11, 2019 at 10:34 AM Patricia Oliveira < > cinzaeamarelo at gmail.com> > wrote: > > Yesterday hospital called me saying Nori could come home. I went there > after work and, while i waited for prescriptions, she started a seizure. > > Vet medicated her so that seizure didn?t complete (diazepam and mannitol). > > I stayed with her sometime, talked to her but i felt it was a farewell. > > When i arrive at home, vet called me to say Nori had a cardiopulmonary > arrest. They reanimated her but it could happen again. > > Less then 30 minutes later, they called me again to say Nori had passed > away. > > As always happens here, when a cat has seizures, brazilian veterinarians > says it is fip. > > I don?t know what she really had, i am very sorrow for didn?t bring her > home on sunday, when she was better. At least, she would have had one more > day at home, with sun bath and love. > > I want to thank all of you. You were the best support i could find for > Nori. > > Thank you very much. > > > > > Patr?cia > > Em ter, 11 de jun de 2019 ?s 00:22, Amani Oakley > escreveu: > > >> We?re all pulling for Nori. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk * On Behalf Of > *Ardy > >> Robertson > >> *Sent:* June 10, 2019 11:21 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hello all ? I?m following Nori?s progress and please know, I?m keeping > >> her in my thoughts and prayers too, hoping the > Stanizolol/Doxy/Prednisolone > >> combo works for her. She has chosen her owners well, thank you for > taking > >> such good care of her. And thanks Amani for the good advice as always. > >> > >> Ardy > >> > >> > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Amani > >> Oakley > >> *Sent:* Saturday, June 8, 2019 9:23 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> One option is to ask your vet to show you how to give her subcutaneous > >> fluids, which I do all the time for my cats if needed. However, for > now, it > >> makes sense to leave her there I guess. I presume they are warming the > IV > >> fluids too, because again, with such a small kitten, it wouldn?t take > much > >> to chill her if the fluids are at room temperature or colder. > >> > >> > >> > >> I guess it?s just me. I am pretty adamant about taking home my cats > >> whenever possible, but I understand that Nori sounds like she needs some > >> extra help. I just find that the cats respond far better to personal > >> cuddling and love, and this makes them feel better, eat more, etc. > >> > >> > >> > >> Hopefully, she will feel better tomorrow. > >> > >> > >> > >> I?m crossing my fingers for you and Nori. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 8, 2019 9:53 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> She has fluids IV all the time and replenishment of potassium. Receives > >> external heating too. > >> > >> > >> > >> They monitor pressure (low sometimes), oxygenation, temperature and > heart > >> rate several times a day. > >> > >> I wish she could come home soon but she has been dehydrated even with > >> fluids IV. I don?t know if it is safe to bring her now. > >> > >> > >> > >> > >> > >> > >> > >> Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> Patricia > >> > >> > >> > >> I agree with you that it is too early to tell, but for sure it is good > >> news that the haematocrit is moving in the right direction. Very good > news > >> on the rosy gingiva. > >> > >> > >> > >> Rouleaux is likely only due to the transfusion. She appears to have had > a > >> bit of transfusion reaction, so the cells may be sticking to one > another as > >> a result. (Red cells in Rouleaux formation means that the look like a > stack > >> of coins ? one on top of the other. In humans, that presentation is > >> consistent with multiple myeloma. I don?t think it means anything right > now > >> other than the new red cells may be reacting a bit with her own cells). > >> > >> > >> > >> I think she is working through the transfusion reaction, so that is > >> likely why she is sleeping because you said that immediately after the > >> transfusion, she was active and eating on her own. > >> > >> > >> > >> Low platelets are consistent with the FeLV presentation and the impact > on > >> the bone marrow. Hopefully, the Stanozolol will help. I seem to recall > that > >> with my Zander, I had the red cell numbers recover first, before the > >> platelets recovered. > >> > >> > >> > >> I presume they have her on a heating pad to keep her body temperature > up. > >> > >> > >> > >> I suspect it might be premature to look at the neurology right now. She > >> is working through a lot, and is a tiny kitten. She needs to be given > time > >> to recover from the transfusion reaction, and to allow the good food and > >> medication to start to work. I don?t know how a neurological diagnosis > >> could help you now, and one would expect the neurologist will have a > >> difficult time seeing a true neurological deficit, with all the rest of > the > >> stuff happening. > >> > >> > >> > >> I would also suggest that at some point, it is better for her to be with > >> you at home. If they are not giving her anything like fluids, you might > >> consider taking her home with you. I know with Zander, he reacted most > >> strongly when I was there with him. I could get him to play a little bit > >> and that made him feel better, and of course, lots of cuddles and > kisses. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 8, 2019 8:52 PM > >> *To:* Sandra Wachtstetter ; > >> felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Thank you, Sandra :) > >> > >> > >> > >> I visited Nori today. The hospital is in another city so I can't go > there > >> every day. > >> > >> > >> > >> She is a rosy gingiva, but continues to sleep most of the time and with > a > >> low temperature. One of the veterinarians there thinks that temperature > is > >> lower because of malnutrition, she has almost no lean mass and no fat. > >> > >> > >> > >> Nori will go through the evaluation of a neurologist tomorrow. Some > >> hypotheses raised for this prostration are neurological, including a > >> possible hypoxia before the first transfusion when her hematocrit was > >> really low. > >> > >> > >> > >> Her blood work today is 30% hematocrit, the higher till now! So i think > >> red cells aren?t being destroyed anymore, is it right or is it early to > >> know? > >> > >> > >> > >> Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low > >> platelets for the first time (92.000). > >> > >> > >> > >> Nori had an echocardiogram today too and it is ok. > >> > >> > >> > >> Thank you! > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter < > >> swacht1946 at comcast.net> escreveu: > >> > >> Hello Patricia, you may already be doing this - but if not, please take > a > >> copy of Amani's conversations for the vet to read - may help. > >> > >> Good luck - don't give up!! > >> > >> Sandt W > >> > >> > >> > >> On June 7, 2019 at 9:55 PM Patricia Oliveira > >> wrote: > >> > >> Nori did not want to eat by herself so they are syringing food. They > >> started another medication for nausea, although she does not vomit, they > >> think that may be why she does not eat. > >> > >> > >> > >> Blood work showed changes in neutrophils (bizarre core?), veternary says > >> it can be from leukemia. > >> > >> > >> > >> The result of this transfusion was not as good as the other time :( > >> > >> > >> > >> i?ll talk to veterinary tomorrow morning again. > >> > >> > >> > >> thank you! > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> > >> > >> > >> > >> Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> Still sounds more like a transfusion reaction than anything with the > meds. > >> > >> > >> > >> Hang in there. See what the afternoon labs show. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 7, 2019 1:44 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Amani > >> > >> > >> > >> Nori is receiving doxy+prenisolone+stanazolol even in the hospital. > >> > >> > >> > >> I know it can be a reaction but i thought higher dose of prednisolone > >> would prevent hemolysis. > >> > >> > >> > >> I also know it's normal for part of the red blood cells to be cleared > >> right after the transfusion, but i don?t remember if it was icteric > plasma > >> on last one. > >> > >> > >> > >> I was hopefull she would come back home tomorrow, now i don?t know if it > >> will be possible. > >> > >> > >> > >> Today she must have am echocardiogram too because x-ray showed an > >> enlarged heart. > >> > >> > >> > >> Thank you! > >> > >> > >> > >> > >> > >> > >> > >> Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> Hi Patricia > >> > >> > >> > >> The Stanozolol often has a side-effect of elevating liver enzymes, > though > >> I cannot remember if it also increased bilirubin (which would be what > would > >> cause the icteric observation of the plasma). However, hang in there. > If it > >> is the Stanozolol, my experience is that the liver enzymes drop right > back > >> to normal, shortly after it is discontinued, and there is no lasting > damage > >> to the liver. For now, what you have described (low temp and slightly > lower > >> heart rate) seems more likely to be related to the transfusion itself, > >> rather than anything else going on. > >> > >> > >> > >> It is also possible that with the additional transfusion, there is a > >> higher than normal red cell destruction going on, which would be another > >> explanation for the increased icterus in the blood (which will also > show as > >> an increase in bilirubin). Elevated bilirubin can often be caused by a > >> reaction to a blood transfusion. If the high bilirubin is the indirect > or > >> the unconjugated portion, it is related to red cell break down. The > direct > >> bilirubin (conjugated portion) is related to liver function. The lab > >> results are usually broken down to Total bilirubin and Direct bilirubin. > >> The indirect portion is obtained by subtracting the direct amount from > the > >> total amount. > >> > >> > >> > >> I myself went through the pressure of the vets wanting me to discontinue > >> the Stanozolol because of abnormal liver enzymes. My logic was that > there > >> was nothing else. If I discontinued the Stanozolol, my cat would die, > >> period. I continued and found that in the end, the liver enzymes > normalized > >> on their own, even though I had Zander on almost continuous Stanozolol > for > >> close to two years. > >> > >> > >> > >> I know that you know that you are only temporarily helping Nori with > >> blood transfusions, and the virus is still attacking cells, etc. In my > >> opinion ? and mine alone ? my experience and research leads me to the > >> conclusion that the combination of Doxycycline/Prednisone/Stanozolol > worked > >> to not only boost the red cell production, but I believe that the > >> Doxycyline assisted in keeping the viruses from properly reproducing. > >> > >> > >> > >> However, anticipate that when the vet gets back the second set of blood > >> work, she may well try to tell you to discontinue the Stanozolol. > >> > >> > >> > >> Amani > >> > >> > >> > >> > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 7, 2019 12:53 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Amani! > >> > >> > >> > >> Nori got another transfusion last night, hematocrit was 11.9 before it. > >> > >> > >> > >> Today morning, i talk to the hospital's veterinarian, she said > hematocrit > >> went to 29 and Nori was fine, all normal parameters and eating by > herself > >> again. > >> > >> > >> > >> But plasma was intensely icteric. I think this means red cells being > >> destroyed, isn't it? > >> > >> > >> > >> About one hour ago, veterinarian said Nori was with low temperature and > >> heart rate slightly lower than normal. She was waiting the new blood > work. > >> In the morning, it was done only hematocrit, not complete blood work. > >> > >> > >> > >> i am worried again. > >> > >> > >> > >> Thank you, > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> I would be leery of the going the route suggested by the vet at this > >> juncture. I seriously seriously doubt if the erythropoietin will help. > See > >> my earlier where I explain why. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 4, 2019 8:53 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Lorraine > >> > >> > >> > >> Veterinary wants to increase prednisolone to immunosuppressive dose and > >> add erythropoietin. She thinks it is immune-mediated anemia and > >> not mycoplasma. > >> > >> > >> > >> Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 > >> kg. > >> > >> > >> > >> We did x-ray today too. No visible tumor but we found a > >> possible cardiopathy ("Increased globular-looking heart silhouette"). > >> > >> > >> > >> :( > >> > >> > >> > >> > >> > >> > >> > >> Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston < > >> johnston1110 at comcast.net> escreveu: > >> > >> Patricia, > >> > >> > >> > >> I would go with the transfusion and also start erythropoietin. > >> Stanozolol is supposed to stimulate erythropoietin production, but she > >> might need a boost of the ready-made drug just to keep her alive until > then. > >> > >> > >> > >> - Lorraine > >> > >> > >> > >> "Sometimes it is the people no one can imagine anything of who do the > >> things no one can imagine." - Alan Turing > >> > >> > >> > >> *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On > Behalf > >> Of *Patricia Oliveira > >> *Sent:* Tuesday, June 4, 2019 6:34 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, > >> > >> > >> > >> We did another blood work today, her hematocrit is 13% now :( > >> > >> > >> > >> She is very sleepy but responsive when i talk to her. > >> > >> > >> > >> I don?t know if i can wait some more days to see if stanozolol is > >> working. Or maybe it would be better get another transfusion right now. > >> > >> > >> > >> Today, vet talk about erythropoietin. Do you know if it can be used with > >> stanozolol? > >> > >> > >> > >> Thank you, > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> Hi Patricia ? I gave all the pills together, morning and evening, except > >> for the metoclopramide which was given ? or so before meals. The rest I > >> gave with the meals. I didn?t observe a problem with giving them > together. > >> > >> > >> > >> You might also try baby food to get Nori to eat. Get the pureed kind > >> (beef or chicken with or without vegetables), so it can be sucked up > into a > >> syringe. If my Zander wasn?t eating (and he wasn?t at the start of the > >> medication regime), then I would use a syringe to get the baby food into > >> him. Baby food is easy to digest and has good things in it. I would > target > >> ? say ? five 3 cc syringe-fulls at each feeding. I would boost the > number > >> of syringe-fulls if possible. Eventually, Zander started eating the baby > >> food on his own, and then I graduated to moist food, and really, > anything > >> he wanted until he put the weight back on. > >> > >> > >> > >> I had a look at the picture you sent and Nori is adorable. I am crossing > >> my fingers for you and for Nori. Keep us updated on her progress. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* June 1, 2019 12:36 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* Re: [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi, Amani! > >> > >> > >> > >> Thanky you very much for you email! > >> > >> > >> > >> Nori was discharged from the hospital yesterday night. She is eating > baby > >> dry food. I tried canned but she didn?t accept so weel. > >> > >> > >> > >> Today i bought other kinds of canned, i'll try them hoping she likes > some > >> one. > >> > >> > >> > >> Compound pharmacy must delivery stanozolol today. > >> > >> > >> > >> Are there any precautions regarding medication schedules? Close or far > to > >> doxy, for example? > >> > >> > >> > >> This is Nori: > >> https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html > >> < > https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html?fbclid=IwAR0cXMedtfi73B81pJI7QiYGwRTJf9VJp-JN7S_Tstb0ANeg0Hm4ObtFH_A > > > >> > >> > >> > >> > >> > >> Thank you! > >> > >> > >> > >> Patr?cia > >> > >> > >> > >> Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley < > aoakley at oakleylegal.com> > >> escreveu: > >> > >> Sorry Patricia ? after going on and on in my last email, I realized I > >> hadn?t actually answered your question. I think you can probably use the > >> stanozolol with the Doxycycline, without the prednisone, but prednisone > >> itself has properties which help to boost red cell production. Try it > out, > >> keep close tabs on the haematology results and see if you are getting a > >> good response on just Doxycycline and the Stanozolol. If not, add the > >> prednisone. You may find that this combination assists with the FIP as > >> well, as per my previous email. > >> > >> > >> > >> Amani > >> > >> > >> > >> *From:* Felvtalk *On Behalf Of > *Patricia > >> Oliveira > >> *Sent:* May 30, 2019 12:56 PM > >> *To:* felvtalk at felineleukemia.org > >> *Subject:* [Felvtalk] Rescued kitten felv + > >> > >> > >> > >> Hi from Brazil, > >> > >> > >> > >> I rescued a very weak, dehydrated, extremely thin kitten. > >> > >> > >> She's hospitalized now. Her hematocrit was 8, had blood transfusion > which > >> raised hematocrit to 22, now it is 19. Low reticulocyte count. > >> > >> She has difficulty walking, which we can not define if it is just > >> weakness or neurological. Already had a seizure. > >> > >> She also have changes in her kidneys. It has been tested and is felv + > >> > >> She is receiving doxy and the hospital vets would like to include > >> prednisolone. > >> > >> However, as it is not possible yet to rule out PIF, and the medication I > >> could use in the case of PIF does not work if the cat received > >> prednisolone, I am trying to avoid it. > >> > >> The veterinarian agreed to prescribe stanozolol. > >> > >> Can it be used without prednisolone, only with doxy she is already > >> receiving? > >> > >> Thank you! > >> > >> > >> > >> Patr?cia > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > >> _______________________________________________ > >> Felvtalk mailing list > >> Felvtalk at felineleukemia.org > >> http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > >> > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > -------------- next part -------------- > An HTML attachment was scrubbed... > URL: < > http://felineleukemia.org/pipermail/felvtalk_felineleukemia.org/attachments/20190611/b723ef5c/attachment.html > > > > ------------------------------ > > Subject: Digest Footer > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > ------------------------------ > > End of Felvtalk Digest, Vol 55, Issue 26 > **************************************** > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > -------------- next part -------------- An HTML attachment was scrubbed... URL: From ardyr at centurytel.net Thu Jun 13 18:46:23 2019 From: ardyr at centurytel.net (Ardy Robertson) Date: Thu, 13 Jun 2019 18:46:23 -0500 Subject: [Felvtalk] Rescued kitten felv + In-Reply-To: References: <002201d51b30$4ff19430$efd4bc90$@net> <1605332536.612607.1560004826102@connect.xfinity.com> <000701d52004$aaf998e0$00eccaa0$@centurytel.net> Message-ID: <006a01d52242$379c1720$a6d44560$@centurytel.net> So very sorry Patricia ? your love kept Nori going probably longer than she would have had. Ardy From: Felvtalk On Behalf Of Patricia Oliveira Sent: Tuesday, June 11, 2019 9:34 AM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Yesterday hospital called me saying Nori could come home. I went there after work and, while i waited for prescriptions, she started a seizure. Vet medicated her so that seizure didn?t complete (diazepam and mannitol). I stayed with her sometime, talked to her but i felt it was a farewell. When i arrive at home, vet called me to say Nori had a cardiopulmonary arrest. They reanimated her but it could happen again. Less then 30 minutes later, they called me again to say Nori had passed away. As always happens here, when a cat has seizures, brazilian veterinarians says it is fip. I don?t know what she really had, i am very sorrow for didn?t bring her home on sunday, when she was better. At least, she would have had one more day at home, with sun bath and love. I want to thank all of you. You were the best support i could find for Nori. Thank you very much. Patr?cia Em ter, 11 de jun de 2019 ?s 00:22, Amani Oakley > escreveu: We?re all pulling for Nori. Amani From: Felvtalk > On Behalf Of Ardy Robertson Sent: June 10, 2019 11:21 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hello all ? I?m following Nori?s progress and please know, I?m keeping her in my thoughts and prayers too, hoping the Stanizolol/Doxy/Prednisolone combo works for her. She has chosen her owners well, thank you for taking such good care of her. And thanks Amani for the good advice as always. Ardy From: Felvtalk > On Behalf Of Amani Oakley Sent: Saturday, June 8, 2019 9:23 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + One option is to ask your vet to show you how to give her subcutaneous fluids, which I do all the time for my cats if needed. However, for now, it makes sense to leave her there I guess. I presume they are warming the IV fluids too, because again, with such a small kitten, it wouldn?t take much to chill her if the fluids are at room temperature or colder. I guess it?s just me. I am pretty adamant about taking home my cats whenever possible, but I understand that Nori sounds like she needs some extra help. I just find that the cats respond far better to personal cuddling and love, and this makes them feel better, eat more, etc. Hopefully, she will feel better tomorrow. I?m crossing my fingers for you and Nori. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 8, 2019 9:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + She has fluids IV all the time and replenishment of potassium. Receives external heating too. They monitor pressure (low sometimes), oxygenation, temperature and heart rate several times a day. I wish she could come home soon but she has been dehydrated even with fluids IV. I don?t know if it is safe to bring her now. Em s?b, 8 de jun de 2019 ?s 22:03, Amani Oakley > escreveu: Patricia I agree with you that it is too early to tell, but for sure it is good news that the haematocrit is moving in the right direction. Very good news on the rosy gingiva. Rouleaux is likely only due to the transfusion. She appears to have had a bit of transfusion reaction, so the cells may be sticking to one another as a result. (Red cells in Rouleaux formation means that the look like a stack of coins ? one on top of the other. In humans, that presentation is consistent with multiple myeloma. I don?t think it means anything right now other than the new red cells may be reacting a bit with her own cells). I think she is working through the transfusion reaction, so that is likely why she is sleeping because you said that immediately after the transfusion, she was active and eating on her own. Low platelets are consistent with the FeLV presentation and the impact on the bone marrow. Hopefully, the Stanozolol will help. I seem to recall that with my Zander, I had the red cell numbers recover first, before the platelets recovered. I presume they have her on a heating pad to keep her body temperature up. I suspect it might be premature to look at the neurology right now. She is working through a lot, and is a tiny kitten. She needs to be given time to recover from the transfusion reaction, and to allow the good food and medication to start to work. I don?t know how a neurological diagnosis could help you now, and one would expect the neurologist will have a difficult time seeing a true neurological deficit, with all the rest of the stuff happening. I would also suggest that at some point, it is better for her to be with you at home. If they are not giving her anything like fluids, you might consider taking her home with you. I know with Zander, he reacted most strongly when I was there with him. I could get him to play a little bit and that made him feel better, and of course, lots of cuddles and kisses. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 8, 2019 8:52 PM To: Sandra Wachtstetter >; felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Thank you, Sandra :) I visited Nori today. The hospital is in another city so I can't go there every day. She is a rosy gingiva, but continues to sleep most of the time and with a low temperature. One of the veterinarians there thinks that temperature is lower because of malnutrition, she has almost no lean mass and no fat. Nori will go through the evaluation of a neurologist tomorrow. Some hypotheses raised for this prostration are neurological, including a possible hypoxia before the first transfusion when her hematocrit was really low. Her blood work today is 30% hematocrit, the higher till now! So i think red cells aren?t being destroyed anymore, is it right or is it early to know? Some red cells in Rouleaux. Leukocytes are still high (> 26.000), low platelets for the first time (92.000). Nori had an echocardiogram today too and it is ok. Thank you! Patr?cia Em s?b, 8 de jun de 2019 ?s 11:40, Sandra Wachtstetter > escreveu: Hello Patricia, you may already be doing this - but if not, please take a copy of Amani's conversations for the vet to read - may help. Good luck - don't give up!! Sandt W On June 7, 2019 at 9:55 PM Patricia Oliveira > wrote: Nori did not want to eat by herself so they are syringing food. They started another medication for nausea, although she does not vomit, they think that may be why she does not eat. Blood work showed changes in neutrophils (bizarre core?), veternary says it can be from leukemia. The result of this transfusion was not as good as the other time :( i?ll talk to veterinary tomorrow morning again. thank you! Patr?cia Em sex, 7 de jun de 2019 ?s 16:13, Amani Oakley < aoakley at oakleylegal.com > escreveu: Still sounds more like a transfusion reaction than anything with the meds. Hang in there. See what the afternoon labs show. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 1:44 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani Nori is receiving doxy+prenisolone+stanazolol even in the hospital. I know it can be a reaction but i thought higher dose of prednisolone would prevent hemolysis. I also know it's normal for part of the red blood cells to be cleared right after the transfusion, but i don?t remember if it was icteric plasma on last one. I was hopefull she would come back home tomorrow, now i don?t know if it will be possible. Today she must have am echocardiogram too because x-ray showed an enlarged heart. Thank you! Em sex, 7 de jun de 2019 ?s 14:18, Amani Oakley > escreveu: Hi Patricia The Stanozolol often has a side-effect of elevating liver enzymes, though I cannot remember if it also increased bilirubin (which would be what would cause the icteric observation of the plasma). However, hang in there. If it is the Stanozolol, my experience is that the liver enzymes drop right back to normal, shortly after it is discontinued, and there is no lasting damage to the liver. For now, what you have described (low temp and slightly lower heart rate) seems more likely to be related to the transfusion itself, rather than anything else going on. It is also possible that with the additional transfusion, there is a higher than normal red cell destruction going on, which would be another explanation for the increased icterus in the blood (which will also show as an increase in bilirubin). Elevated bilirubin can often be caused by a reaction to a blood transfusion. If the high bilirubin is the indirect or the unconjugated portion, it is related to red cell break down. The direct bilirubin (conjugated portion) is related to liver function. The lab results are usually broken down to Total bilirubin and Direct bilirubin. The indirect portion is obtained by subtracting the direct amount from the total amount. I myself went through the pressure of the vets wanting me to discontinue the Stanozolol because of abnormal liver enzymes. My logic was that there was nothing else. If I discontinued the Stanozolol, my cat would die, period. I continued and found that in the end, the liver enzymes normalized on their own, even though I had Zander on almost continuous Stanozolol for close to two years. I know that you know that you are only temporarily helping Nori with blood transfusions, and the virus is still attacking cells, etc. In my opinion ? and mine alone ? my experience and research leads me to the conclusion that the combination of Doxycycline/Prednisone/Stanozolol worked to not only boost the red cell production, but I believe that the Doxycyline assisted in keeping the viruses from properly reproducing. However, anticipate that when the vet gets back the second set of blood work, she may well try to tell you to discontinue the Stanozolol. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 7, 2019 12:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Nori got another transfusion last night, hematocrit was 11.9 before it. Today morning, i talk to the hospital's veterinarian, she said hematocrit went to 29 and Nori was fine, all normal parameters and eating by herself again. But plasma was intensely icteric. I think this means red cells being destroyed, isn't it? About one hour ago, veterinarian said Nori was with low temperature and heart rate slightly lower than normal. She was waiting the new blood work. In the morning, it was done only hematocrit, not complete blood work. i am worried again. Thank you, Patr?cia Em ter, 4 de jun de 2019 ?s 23:46, Amani Oakley > escreveu: I would be leery of the going the route suggested by the vet at this juncture. I seriously seriously doubt if the erythropoietin will help. See my earlier where I explain why. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 4, 2019 8:53 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Lorraine Veterinary wants to increase prednisolone to immunosuppressive dose and add erythropoietin. She thinks it is immune-mediated anemia and not mycoplasma. Nori is receiving 1,2 mg prednisolone, twice a day. She weighs only 1 kg. We did x-ray today too. No visible tumor but we found a possible cardiopathy ("Increased globular-looking heart silhouette"). :( Em ter, 4 de jun de 2019 ?s 20:50, Lorraine Johnston > escreveu: Patricia, I would go with the transfusion and also start erythropoietin. Stanozolol is supposed to stimulate erythropoietin production, but she might need a boost of the ready-made drug just to keep her alive until then. - Lorraine "Sometimes it is the people no one can imagine anything of who do the things no one can imagine." - Alan Turing From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org ] On Behalf Of Patricia Oliveira Sent: Tuesday, June 4, 2019 6:34 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, We did another blood work today, her hematocrit is 13% now :( She is very sleepy but responsive when i talk to her. I don?t know if i can wait some more days to see if stanozolol is working. Or maybe it would be better get another transfusion right now. Today, vet talk about erythropoietin. Do you know if it can be used with stanozolol? Thank you, Patr?cia Em s?b, 1 de jun de 2019 ?s 14:44, Amani Oakley > escreveu: Hi Patricia ? I gave all the pills together, morning and evening, except for the metoclopramide which was given ? or so before meals. The rest I gave with the meals. I didn?t observe a problem with giving them together. You might also try baby food to get Nori to eat. Get the pureed kind (beef or chicken with or without vegetables), so it can be sucked up into a syringe. If my Zander wasn?t eating (and he wasn?t at the start of the medication regime), then I would use a syringe to get the baby food into him. Baby food is easy to digest and has good things in it. I would target ? say ? five 3 cc syringe-fulls at each feeding. I would boost the number of syringe-fulls if possible. Eventually, Zander started eating the baby food on his own, and then I graduated to moist food, and really, anything he wanted until he put the weight back on. I had a look at the picture you sent and Nori is adorable. I am crossing my fingers for you and for Nori. Keep us updated on her progress. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: June 1, 2019 12:36 PM To: felvtalk at felineleukemia.org Subject: Re: [Felvtalk] Rescued kitten felv + Hi, Amani! Thanky you very much for you email! Nori was discharged from the hospital yesterday night. She is eating baby dry food. I tried canned but she didn?t accept so weel. Today i bought other kinds of canned, i'll try them hoping she likes some one. Compound pharmacy must delivery stanozolol today. Are there any precautions regarding medication schedules? Close or far to doxy, for example? This is Nori: https://catsnecropolis.blogspot.com/2019/06/nori-teve-alta.html Thank you! Patr?cia Em qui, 30 de mai de 2019 ?s 20:52, Amani Oakley > escreveu: Sorry Patricia ? after going on and on in my last email, I realized I hadn?t actually answered your question. I think you can probably use the stanozolol with the Doxycycline, without the prednisone, but prednisone itself has properties which help to boost red cell production. Try it out, keep close tabs on the haematology results and see if you are getting a good response on just Doxycycline and the Stanozolol. If not, add the prednisone. You may find that this combination assists with the FIP as well, as per my previous email. Amani From: Felvtalk > On Behalf Of Patricia Oliveira Sent: May 30, 2019 12:56 PM To: felvtalk at felineleukemia.org Subject: [Felvtalk] Rescued kitten felv + Hi from Brazil, I rescued a very weak, dehydrated, extremely thin kitten. She's hospitalized now. Her hematocrit was 8, had blood transfusion which raised hematocrit to 22, now it is 19. Low reticulocyte count. She has difficulty walking, which we can not define if it is just weakness or neurological. Already had a seizure. She also have changes in her kidneys. It has been tested and is felv + She is receiving doxy and the hospital vets would like to include prednisolone. However, as it is not possible yet to rule out PIF, and the medication I could use in the case of PIF does not work if the cat received prednisolone, I am trying to avoid it. The veterinarian agreed to prescribe stanozolol. Can it be used without prednisolone, only with doxy she is already receiving? Thank you! Patr?cia _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk at felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Sat Jun 15 12:09:35 2019 From: johnston1110 at comcast.net (Lorraine Johnston) Date: Sat, 15 Jun 2019 13:09:35 -0400 Subject: [Felvtalk] FDA Increases Total Individual Award Amount for Minor Use/Minor Species Grants Message-ID: <008701d5239d$1c54e120$54fea360$@net> Perhaps there will be additional funding for FeLV research resulting from this change. - Lorraine If your email program has trouble displaying this email, view it as a web page . FDA Increases Total Individual Award Amount for Minor Use/Minor Species Grants Application period opens June 14, 2019 The U.S. Food and Drug Administration today announced an open period for applications for grants to support the development and approval or conditional approval of new animal drugs intended to treat uncommon diseases (minor uses) in major species (horses, dogs, cats, cattle, pigs, turkeys and chickens) or to treat minor species (MUMS). The individual award amount has been increased to a single funding level up to $250,000. The Minor Use and Minor Species Animal Health Act of 2004 (the MUMS act) provides innovative ways to bring products to market for these small populations and is designed to help veterinary pharmaceutical companies and others overcome the financial roadblocks they face in providing animal drugs for a limited market. Before this legislation, veterinary pharmaceutical companies and others would rarely attempt to bring such drugs to market. The MUMS act established the grant program. Grants awarded through the MUMS program support the FDA?s continuing mission to assure that safe and effective animal drugs are available for a wide range of species and conditions. Read more U.S. Food and Drug Administration 10903 New Hampshire Avenue, Silver Spring, MD 20993 1-888-INFO-FDA (1-888-463-6332) Privacy Policy | www.fda.gov -------------- next part -------------- An HTML attachment was scrubbed... URL: From johnston1110 at comcast.net Sun Jun 16 11:52:26 2019 From: johnston1110 at comcast.net (Lorraine Johnston) Date: Sun, 16 Jun 2019 12:52:26 -0400 Subject: [Felvtalk] Happy Father's Day Message-ID: <001701d52463$e11b4280$a351c780$@net> In the US, today is Father's Day. We wish all cat fathers in our group, in the US and worldwide, a happy Father's Day. Thank you for loving your FeLV cats and caring so well for them. Best regards, - Lorraine and Larry -------------- next part -------------- An HTML attachment was scrubbed... URL: From thyme2sail at gmail.com Sun Jun 16 15:50:22 2019 From: thyme2sail at gmail.com (Pam Doore) Date: Sun, 16 Jun 2019 16:50:22 -0400 Subject: [Felvtalk] FDA Increases Total Individual Award Amount for Minor Use/Minor Species Grants In-Reply-To: <008701d5239d$1c54e120$54fea360$@net> References: <008701d5239d$1c54e120$54fea360$@net> Message-ID: <728EFC34-FC20-4247-B6FB-05A156084264@gmail.com> That sure would be nice! > On Jun 15, 2019, at 1:09 PM, Lorraine Johnston wrote: > > Perhaps there will be additional funding for FeLV research resulting from this change. > > - Lorraine > > > If your email program has trouble displaying this email, view it as a web page . > > > > > > FDA Increases Total Individual Award Amount for Minor Use/Minor Species Grants > > > Application period opens June 14, 2019 > > The U.S. Food and Drug Administration today announced an open period for applications for grants to support the development and approval or conditional approval of new animal drugs intended to treat uncommon diseases (minor uses) in major species (horses, dogs, cats, cattle, pigs, turkeys and chickens) or to treat minor species (MUMS). The individual award amount has been increased to a single funding level up to $250,000. > > The Minor Use and Minor Species Animal Health Act of 2004 (the MUMS act) provides innovative ways to bring products to market for these small populations and is designed to help veterinary pharmaceutical companies and others overcome the financial roadblocks they face in providing animal drugs for a limited market. Before this legislation, veterinary pharmaceutical companies and others would rarely attempt to bring such drugs to market. The MUMS act established the grant program. > > Grants awarded through the MUMS program support the FDA?s continuing mission to assure that safe and effective animal drugs are available for a wide range of species and conditions. > > > Read more > > > > > U.S. Food and Drug Administration > 10903 New Hampshire Avenue, Silver Spring, MD 20993 > 1-888-INFO-FDA (1-888-463-6332) > Privacy Policy | www.fda.gov > > > _______________________________________________ > Felvtalk mailing list > Felvtalk at felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org -------------- next part -------------- An HTML attachment was scrubbed... URL: