[Felvtalk] FeLv Positive cat

[Amani Oakley]

Hi Molly

I tried Immunoregulin for a long time with my FeLV little boy, but it was completely ineffective. You need to be doing regular (weekly or every other week) blood testing, to monitor whether the Immunoregulin is helping or not.

If not, then don’t run through the full 21 weeks. There would be no point and you will waste valuable time while she worsens.

I had good luck using a combination of Doxycycline (1/2 100 mg twice a day) plus Winstrol (1 mg x2 day) plus prednisone/prednisolone (1/2 5 mg tablet x2 a day). Even on this protocol, I recommend close weekly or bi-weekly monitoring so you can see if you start getting a rise in the red cell indices, etc. Don’t let your vet talk you out of one or another of these medications. You can’t substitute another antibiotic for the Doxycycline, for example. Doxycycline has anti-RNA properties (which allows it to interfere with the replication of viruses when other antibiotics don’t do this.)

Some people in this group have also reported excellent results with “Zander’s Protocol” while others have not. I am hypothesizing that this may be due to the fact that it appears there may be as many as five different strains of the virus, so perhaps the different strains respond or don’t respond to certain things. The other thing that may affect outcome is timing. The virus shuts down the bone marrow by killing or taking over the cells in the bone marrow. At some point, there will be little in the bone marrow to turn back on (which it appears the Winstrol can do in some instances).

Amani

P.S. – For those of you keeping score, I have corrected my previous description of Zander’s Protocol because I found an old pill bottle and realized I had been giving him ½ a 100 mg Doxy tablet twice a day, not a ¼ tablet as I had previously reported. Sorry for any confusion.

From: Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] On Behalf Of Molly Mou
Sent: February-24-17 9:57 PM
To: felvtalk at felineleukemia.org
Subject: [Felvtalk] FeLv Positive cat

I am new to the list. Three weeks ago my 5-year old Mia kitty was diagnosed with FeLv. The ELISA test showed slightly + for FeLv. I took her to the vet’s initially because her lymph nodes were raging – all of them premandibular, prescapular, inguinal all the way to the popliteals were enlarged.
A needle aspirate of the lymph nodes result was hyperplasia, no lymphosarcoma. White blood cell count was normal, but she was anemic, but not to the point of needing a transfusion.
I was devastated and stunned at this diagnosis because she (the whole litter) was tested as kittens for FIV and FeLv and were negative. My vet said the disease can stay in the bone marrow. I have her brother who is asymptomatic – confusing. I haven’t had him tested yet for FeLv yet.
My vet recommended treatment with Immunoregulin. The protocol per Plumb’s is an IV injection twice weekly for two weeks, then 1 injection once weekly for 21 weeks. She is now in her 4th week of treatment.
For the first two weeks, her lymph nodes decreased and became softer. But after the 2nd week her lymph nodes are raging again despite the treatments. She is eating well, but not very active.
Has anyone had experience with this treatment or any other treatment(s) or advice to help my little girl?

Thanks in advance,

Pat Peterson
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