[Felvtalk] Michael's last hope

Fri Feb 17 23:28:12 CST 2017

Im sorry for both you, michael and your parents. Unfortunately, it's for
the best. At least you know that you and your famiy did everything you
could do for Mikey and that when he passes, he will be surrounded with the
people who love him. :'-(

On Feb 17, 2017 7:19 PM, "Terri Knight" <tkmoocow at gmail.com> wrote:

> So my last email I sent a few days ago didn't seem to go through as it
> needed to be moderated due to its size. I attached a pic of the blood test
> results which clearly the system didn't like. This was my email:
>
> Update.
>
> So Michael was first put on Epo a few weeks ago due to the suggestions of
> specialists that my vet contacted, he was not on it for long as the vet
> could see it was not working. I then organized to get Winstrol for him, he
> started it on 1 February but due to his blood count being super low he had
> to have a second transfusion on 3 February to give the Winstrol a chance to
> work. He is still on Doxy as far as I know and cortisone. He visited the
> vet yesterday (14 Feb) with this update: his red blood cells are still
> dropping, but his platelets are up and the vet said he had a bit more
> colour in his mouth and tongue, he has lost a bit more weight and was
> running a slight temperature so his medrol (not sure what that is) was
> upped for 3 days, back to the vet on 17 Feb. So kind of mixed results but
> still not looking good with the red blood cell production.
>
> Unfortunately his latest test results shows a decline again, his red blood
> cells went from 10.42% on Tuesday to 8.18% on Friday and there is nothing
> more that can be done. At his current rate of decline he will reach
> critical levels by Monday.
>
> My parents and I (but mostly my parents since I'm on the other side of the
> world) have to make a heartbreaking decision of when it's time for Mikey.
> The vet says that when he reaches 6% he will be feeling terrible and to add
> to this he has no more energy he just lies down in one spot all the time.
>
> It is with a heavy heart and tears in my eyes that I have accept his fate
> on top of being so far away from him.
>
> Terri
>
>
> On 22 Jan 2017 09:49, "Amani Oakley" <aoakley at oakleylegal.com> wrote:
>
> I probably can’t attach the actual papers regarding the use of Stanazolol
> (Winstrol) in osteoporosis, but the title of one of the papers is: *Stanozolol
> in postmenopausal osteoporosis: therapeutic efficacy and possible
> mechanisms of action.*
>
>
>
> Here is the abstract of the paper:
>
>
>
> *To assess the efficacy of the anabolic steroid stanozolol in the
> treatment of osteoporosis, a 29-month double-blind study was performed with
> 23 treated and 23 control postmenopausal osteoporotic women. Drug efficacy
> was assessed by serial determinations of total body calcium (TBC--total
> bone mass) by neutron activation analysis, regional bone mass (RBM) by
> single-photon absorptiometry, and by spinal roentgenograms. Total body
> calcium increased 4.4% from baseline values (P less than 0.01) in the
> treated group and remained unchanged in the control group; the difference
> in the change in TBC between the treated and control groups was significant
> (P less than 0.03). The effect of the drug on TBC persisted throughout the
> 29-month period. In contrast to TBC, measurements of RBM indicated no
> significant differences between the treated and placebo groups, suggesting
> a possible differential response to therapy at various skeletal sites. No
> new spinal compression fractures were noted in the treated group (compared
> with three new fractures in the control group). Assessment of serum and
> urine values indicated a decrease in the level of urinary calcium and an
> increase in the level of total urinary cyclic AMP in the treated group.
> These changes were observed even though the level of serum iPTH was
> significantly decreased during the study. An analysis of changes in bone
> biopsy specimens revealed no significant differences between the treated
> and control groups. Seventy-six percent of the treated subjects developed
> SGOT elevations or other side effects from the stanozolol therapy; at no
> time were these effects sufficiently severe to cause termination of
> medication. The data suggest that long-term use of stanozolol increases the
> net total bone mass above pretreatment levels.*
>
>
>
> Amani
>
>
>
> *From:* Felvtalk [mailto:felvtalk-bounces at felineleukemia.org] *On Behalf
> Of *Terri Knight
>
> *Sent:* January-21-17 1:12 PM
> *To:* felvtalk at felineleukemia.org
> *Subject:* Re: [Felvtalk] Michael's last hope
>
>
>
> So an update.
>
>
>
> I had to leave to start working in South Korea without my baby Mike, but I
> left him in my parents capable hands. They have done a great job and
> Michael's vet has been great with doing research and getting new options
> from specialists.
>
>
>
> I spoke to my vet about Amani's advice and he explained what those drugs
> were for and what we were doing already, Michael is in South Africa so we
> don't always get the same drugs or they have different names.
>
>
>
> He was already on a cortisone injection which was a better option than the
> tablet form (until he improves), he was more than willing to give Michael
> the anabolic steroid but said that it doesn't actually do anything for
> production of anything in the bone marrow it is to help with appetite, and
> he was already on Baytril which was similar to Doxycycline but without
> the common side effect of nausea. He did change him to Doxy with strict
> instructions to give it to him with food and watch his reaction to it.
>
>
>
> Just before I left Michael went for blood count again and was still
> steadily dropping, the vet got got hold of specialists but no good news.
> After I left my dad told me our vet spoke to more specialists and we had a
> new option. He gets an injection every few days and the vet said we should
> see where it will lead by Monday. I'm not sure what the new meds are but my
> mom has joined this mailing list and my dad will soon too. I told the to
> keep this platform updated and I will too.
>
>
>
> Terri
>
>
>
> On 12 Jan 2017 07:24, <dlgegg at windstream.net> wrote:
>
> when i had cncer, they gave me epogen.  i had a reaction to it and they
> stopped.
>
> ---- gidget43 at aol.com wrote:
> > Terri,  I saw this post and am praying for your little Michael!  Can
> they start him on Aranesp (darbepoetin) or Epogen, or even Winstrol (which
> I think has been mentioned here before?).  I know with Aranesp, you give
> the shot 1 time a week and when it is within normal range, begin to space
> out the injections to find the right dose to  hold it in that normal
> range.  Epogen is given 3 times a week and when in normal range, one dosage
> is skipped and they search for that perfect dosage.
> >
> >
> > Could you get a copy of that most recent blood work as I can read blood
> work and am wondering if anything else is off. IF so, once it is treated,
> things may go back into place with other levels.  This is what happened to
> my baby Kit.  I immediately put her on Rx Vitamins for Pets ~ Liquid
> Immuno.  Also she was put on antibiotics for fever and infection.  I really
> would like to see the blood work.  If you want, you can send to me
> privately at Gidget43 at aol.com
> >
> >
> > Nancy
> >
> >
> >
> > -----Original Message-----
> > From: Terri <tkmoocow at gmail.com>
> > To: felvtalk <felvtalk at felineleukemia.org>
> > Sent: Tue, Jan 10, 2017 6:52 pm
> > Subject: [Felvtalk] Michael's last hope
> >
> >
> >
> > Hi everyone.
> >
> > My little boy Michael is 3 and was diagnosed just over a week ago. I
> noticed he had lost weight and wasn’t quite himself but nothing major, or
> so I thought. I got him as a stray kitten, had him tested – he was negative
> for felv, and vaccinated him every year.
> >
> > On Fri 30 Dec I took him to the vet, she did blood tests to check what
> could be wrong with him and told me that when he came up positive she
> didn’t do any further tests. She said he was anemic and prescribed
> cortisone every day and vitamin B shots every week for 4 weeks. I asked
> what his lifespan would be and she told me not very long and that there was
> nothing else we could do except a blood transfusion at some stage.
> >
> > After coming home from a new years eve party I found him limping and he
> would not stop moaning, I gave him an anti inflammatory that he had been
> given for a previous leg injury hoping it would help until morning when a
> vet opened. It helped his leg but he started moaning again 2 hours later. I
> finally found a vet that could help on new years day. I told the vet about
> his history and what had happened earlier that morning, by this time his
> leg was fine so the vet gave him a strong pain killer thinking he was
> moaning in pain and told me to bring him back later if it didn’t help. I
> took him back where a different vet saw him, he did blood tests and the
> results were terrible, he also felt that he had some sort of neurological
> issue so he had to be admitted to hospital. His platelet and red blood cell
> count was extremely low and he was not responding to treatment, I made the
> decision for him to have a blood transfusion which he received on 3 Jan
> Tuesday evening. I fetched him on Wednesday and had him tested again on the
> Friday, his results were still better but there was no sign of his body
> regenerating. On the weekend he just seemed to improve so much, is appetite
> was back and he had interest in playing like his old self again, but
> Monday’s results did not reflect his behavior. His body was not
> regenerating and his counts had dropped slightly.
> >
> > My next step is blood tests and decisions on Friday. I am devastated and
> don’t know if there is anything else that we can do. If anyone can give any
> advice or suggestions I would really appreciate it. At the moment he is on
> Baytril and a nutritional tonic.
> >
> > Kind regards,
> > Terri Knight
> >
> > Sent from Mail for Windows 10
> >
> >
> > _______________________________________________
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> >
>
>
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